UniProtKB - F1QXS0 (F1QXS0_DANRE)
Protein
Submitted name:
Methyl-CpG-binding domain protein 3b
Gene
mbd3b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 163 – 170 | ATPPROSITE-ProRule annotation | 8 |
GO - Molecular functioni
- actin filament binding Source: InterPro
- ATP binding Source: UniProtKB-UniRule
- motor activity Source: UniProtKB-UniRule
GO - Biological processi
- definitive hemopoiesis Source: ZFIN
- hematopoietic progenitor cell differentiation Source: ZFIN
Keywordsi
Molecular function | Actin-bindingPROSITE-ProRule annotationARBA annotation, Motor protein, MyosinPROSITE-ProRule annotationARBA annotation |
Ligand | ATP-bindingPROSITE-ProRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Methyl-CpG-binding domain protein 3bImported |
Gene namesi | Name:mbd3bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-030131-9792, mbd3b |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000061810, Expressed in intestine and 17 other tissues |
ExpressionAtlasi | F1QXS0, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 69 – 754 | Myosin motorInterPro annotationAdd BLAST | 686 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 630 – 652 | Actin-bindingPROSITE-ProRule annotationAdd BLAST | 23 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 906 – 972 | Sequence analysisAdd BLAST | 67 | |
Coiled coili | 981 – 1029 | Sequence analysisAdd BLAST | 49 |
Sequence similaritiesi
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000155402 |
HOGENOMi | CLU_000192_3_1_1 |
OMAi | GKWELGK |
Family and domain databases
CDDi | cd01380, MYSc_Myo5, 1 hit |
Gene3Di | 2.30.30.360, 1 hit 3.40.850.10, 1 hit |
InterProi | View protein in InterPro IPR000048, IQ_motif_EF-hand-BS IPR036961, Kinesin_motor_dom_sf IPR001609, Myosin_head_motor_dom IPR008989, Myosin_S1_N IPR036103, MYSc_Myo5 IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00612, IQ, 4 hits PF00063, Myosin_head, 1 hit |
PRINTSi | PR00193, MYOSINHEAVY |
SMARTi | View protein in SMART SM00015, IQ, 6 hits SM00242, MYSc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS50096, IQ, 4 hits PS51456, MYOSIN_MOTOR, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F1QXS0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XSSCFCWLSQ GACVWVPDPE AVWVSAQLLQ DYSPGDQQIS IQLPDGREME
60 70 80 90 100
YPVLPPAGLP PLGNPDILEG ENDLTALTFL HEPAVLHNLR VRFLDYSSIY
110 120 130 140 150
TYCGIVLVAL NPYEPLPIYG EEVIDAYSGQ DMADMEPHIF SVAEEAYRTM
160 170 180 190 200
IREEKNQSII ISGESGSGKT VSAKFTMRYF AVVGGAAQQT SVEEKVLASN
210 220 230 240 250
PIMEAIGNAK TTRNDNSSRF GKYIEIGFGC KGDIIGANMR TYLLEKSRVV
260 270 280 290 300
FQAADERNYH IFYQLCASRD LPELRTLRLD SAENFHYTNQ GQDVHISGTD
310 320 330 340 350
DVVELERTRN AFTILGKECK QTSRWRYFVS WQLFFTWGMS TYKPAVVGDD
360 370 380 390 400
RSLAVFAKLL RVEGAQMAQW LCHRRLAVGG EMLVKPMTGQ QANEARDALA
410 420 430 440 450
KHVYEQLFTW TVQRLNSSLR AHREKPKSFT GVLDIYGFET FDRNSFEQFC
460 470 480 490 500
INYANEKLQQ QFNRHVFQLE QEEYLREELP WNRIEFSDNQ PCIALIEGQL
510 520 530 540 550
GLLDLLDEEC RMPKGSDDNW ARKLYDQHLN HSPHFLKPRM SNSAFIIVHF
560 570 580 590 600
ADKVQYECDG FLDKNRDTVF EEPINILRAS QSELVAELFQ KESAGGCLPN
610 620 630 640 650
STLANGSVRS GKRAHREHKL TVGFQFRQSL QLLMDTLNST TPHYVRCIKS
660 670 680 690 700
NDLKKPFLFD PKRAVQQLRA CGVLETIQIS AAGYPSRQVY LWTYEEFFAR
710 720 730 740 750
YRVLLQGFVS QDDVRHSCQS TLPDLIPDPE QYCFGKTKVF FRAGQVAVLE
760 770 780 790 800
KLRGDRLHAA GVLIQSWVRG WQQRRHYQRL RQATSILQRY TRGTLARRLA
810 820 830 840 850
WTLRYTRAAL IIQKTYRMLA VRQLYLTIRG ATIKIQAFIR GTKARRIYSQ
860 870 880 890 900
MLTERAVVIL QARVRGWLAR SSYRRIRGAV VLMQCCVRRR AARRELLRLR
910 920 930 940 950
ADARSVEKYR ELNKGMEVKL MQLQLRADQQ ARESASLRET LQTERDAHTS
960 970 980 990 1000
ELENLHSSLL KLQNQLKESI NTAPLVSQKQ EEEWRRAEEK AKQEILQLTQ
1010 1020 1030
EIQALRVDRD SLQKERDSLA IRLQDQEKAQ E
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8QPC3 | A0A2R8QPC3_DANRE | Methyl-CpG-binding domain protein 3... | mbd3b | 265 | Annotation score: | ||
A0A0R4IA78 | A0A0R4IA78_DANRE | Methyl-CpG-binding domain protein 3... | mbd3b | 265 | Annotation score: | ||
F1QL92 | F1QL92_DANRE | Methyl-CpG-binding domain protein 3... | mbd3b | 242 | Annotation score: | ||
F1QPJ2 | F1QPJ2_DANRE | Methyl-CpG-binding domain protein 3... | mbd3b | 401 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 | |
Non-terminal residuei | 1031 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX005203 Genomic DNA No translation available. FO704670 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000132951; ENSDARP00000114041; ENSDARG00000061810 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX005203 Genomic DNA No translation available. FO704670 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Genome annotation databases
Ensembli | ENSDART00000132951; ENSDARP00000114041; ENSDARG00000061810 |
Organism-specific databases
ZFINi | ZDB-GENE-030131-9792, mbd3b |
Phylogenomic databases
GeneTreei | ENSGT00940000155402 |
HOGENOMi | CLU_000192_3_1_1 |
OMAi | GKWELGK |
Gene expression databases
Bgeei | ENSDARG00000061810, Expressed in intestine and 17 other tissues |
ExpressionAtlasi | F1QXS0, baseline |
Family and domain databases
CDDi | cd01380, MYSc_Myo5, 1 hit |
Gene3Di | 2.30.30.360, 1 hit 3.40.850.10, 1 hit |
InterProi | View protein in InterPro IPR000048, IQ_motif_EF-hand-BS IPR036961, Kinesin_motor_dom_sf IPR001609, Myosin_head_motor_dom IPR008989, Myosin_S1_N IPR036103, MYSc_Myo5 IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF00612, IQ, 4 hits PF00063, Myosin_head, 1 hit |
PRINTSi | PR00193, MYOSINHEAVY |
SMARTi | View protein in SMART SM00015, IQ, 6 hits SM00242, MYSc, 1 hit |
SUPFAMi | SSF52540, SSF52540, 2 hits |
PROSITEi | View protein in PROSITE PS50096, IQ, 4 hits PS51456, MYOSIN_MOTOR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1QXS0_DANRE | |
Accessioni | F1QXS0Primary (citable) accession number: F1QXS0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 3, 2011 | |
Last modified: | October 7, 2020 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |