Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Transient receptor potential cation channel, subfamily C, member 6b

Gene

trpc6b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-DRE-114508 Effects of PIP2 hydrolysis
R-DRE-139853 Elevation of cytosolic Ca2+ levels
R-DRE-3295583 TRP channels

Names & Taxonomyi

Protein namesi
Submitted name:
Transient receptor potential cation channel, subfamily C, member 6bImported
Gene namesi
Name:trpc6bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-081030-19 trpc6b

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei334 – 354HelicalSequence analysisAdd BLAST21
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Transmembranei418 – 435HelicalSequence analysisAdd BLAST18
Transmembranei455 – 478HelicalSequence analysisAdd BLAST24
Transmembranei518 – 539HelicalSequence analysisAdd BLAST22
Transmembranei559 – 581HelicalSequence analysisAdd BLAST23
Transmembranei630 – 652HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1QWI1

Expressioni

Gene expression databases

BgeeiENSDARG00000067730 Expressed in 11 organ(s), highest expression level in motor nucleus of trigeminal nerve

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000088318

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 82ANK_REP_REGIONInterPro annotationAdd BLAST51

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili786 – 810Sequence analysisAdd BLAST25

Keywords - Domaini

ANK repeatSAAS annotation, Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3609 Eukaryota
ENOG410XQ0Y LUCA
GeneTreeiENSGT00760000119180
InParanoidiF1QWI1
OMAiSHICFLV
OrthoDBiEOG091G01FB
TreeFamiTF313147

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR005821 Ion_trans_dom
IPR004729 TRP_channel
IPR013555 TRP_dom
IPR005462 TRPC6_channel
IPR002153 TRPC_channel
PANTHERiPTHR10117 PTHR10117, 2 hits
PTHR10117:SF7 PTHR10117:SF7, 2 hits
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF00520 Ion_trans, 1 hit
PF08344 TRP_2, 1 hit
PRINTSiPR01097 TRNSRECEPTRP
SMARTiView protein in SMART
SM00248 ANK, 4 hits
SUPFAMiSSF48403 SSF48403, 1 hit
TIGRFAMsiTIGR00870 trp, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

F1QWI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
XKSRRMAMRR PAHMFNARYN NLSPTEERFL EAAEYGNIPV IRRMLEELPE
60 70 80 90 100
LNVNCVDYMG QNALQLAVAN EHLEVTELLL KKENLARIGD ALLLAISKGY
110 120 130 140 150
IRIVEAILSH QAFADTTKLT SSPLQAETQD DFFAYDEDGT RFSHDITPII
160 170 180 190 200
LASHCHEYEI VHILLRKGAC IARPHDYFCK CNGCLYHQRH DSFSHSRSRI
210 220 230 240 250
NAYKGLASPA YLSLSSEDPV LTALELSNEL AVLANIEKEF KNDYKTLSMQ
260 270 280 290 300
CKDFVVGLLD LCRNTEEVEA ILNGDTEAGG HFDKGDRPNL VRLKLAIKYE
310 320 330 340 350
LKKFVAHPNC QQQLLSIWYE NLSGLRQQTT AVKLLVVLGV VVGLPILALL
360 370 380 390 400
YWIAPSSKLG KIIRGPFLKF VAHAASFTIF LGLLIMNAAD RFEGTSLLPN
410 420 430 440 450
MTIHDHPSQL FRMKTTPFTW MEMLIISWVV GMIWAECKEI WSLGPREYLL
460 470 480 490 500
EPWNLLDFGM LAIFVTSFIA RFMAFYHANV AQNYVDKRYT DLSNITLPLE
510 520 530 540 550
IEYYRLARVH WVPSDPQLIS EGLYAIAVVL SFSRIAYILP ANESFGPLQI
560 570 580 590 600
SLGRTVKDIF KFMVIFIMVF VAFMIGMFNL YSYYRGAKQN GAFTTVEESF
610 620 630 640 650
KTLFWAIFGL SEVKSVVINN GHKFIENIGY VLYGVYNVTM VIVLLNMLIA
660 670 680 690 700
MINNSFQEIE DDADVEWKFA RAKLWFSYFE EGGTLPVPFN LIPSPKSVIS
710 720 730 740 750
LAMRLKRLLL IPLHRHKEDL KEDTELNESG KQKESSEKNS PHTSRYQRIM
760 770 780 790 800
KRLIKRYVIK AQTDKEGDEV NEGELKEIKQ DISSLRFELL EEKSRQTEEL
810
AELVRRLEER LISQYKI
Length:817
Mass (Da):93,707
Last modified:May 16, 2012 - v2
Checksum:iC8947338DB720A4A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8QEW3A0A2R8QEW3_DANRE
Transient receptor potential cation...
trpc6b
705Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU459064 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000097547; ENSDARP00000088318; ENSDARG00000067730

Similar proteinsi

Entry informationi

Entry nameiF1QWI1_DANRE
AccessioniPrimary (citable) accession number: F1QWI1
Secondary accession number(s): F8VNM8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 16, 2012
Last modified: September 12, 2018
This is version 45 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again