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UniProtKB - F1QUS0 (F1QUS0_DANRE)
Protein
Calretinin
Gene
calb2b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
ARBA annotationGO - Molecular functioni
- calcium ion binding Source: GO_Central
GO - Biological processi
- regulation of cytosolic calcium ion concentration Source: GO_Central
- regulation of long-term synaptic potentiation Source: GO_Central
- regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central
Keywordsi
Ligand | CalciumARBA annotation, Metal-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: CalretininARBA annotation |
Gene namesi | Name:calb2bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-040426-1668, calb2b |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Nucleus
- nucleus Source: GO_Central
Other locations
- dendrite Source: GO_Central
- neuron projection Source: GO_Central
- synapse Source: GO_Central
- terminal bouton Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSDARG00000036344, Expressed in retina and 36 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 51 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 61 – 96 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 105 – 140 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 149 – 184 | EF-handInterPro annotationAdd BLAST | 36 | |
Domaini | 193 – 228 | EF-handInterPro annotationAdd BLAST | 36 |
Sequence similaritiesi
Belongs to the calbindin family.ARBA annotation
Phylogenomic databases
eggNOGi | KOG0027, Eukaryota |
GeneTreei | ENSGT00950000183108 |
HOGENOMi | CLU_054826_1_1_1 |
InParanoidi | F1QUS0 |
OMAi | WSHYDRD |
PhylomeDBi | F1QUS0 |
TreeFami | TF325083 |
Family and domain databases
InterProi | View protein in InterPro IPR029646, CALB2 IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom |
PANTHERi | PTHR19972:SF4, PTHR19972:SF4, 1 hit |
Pfami | View protein in Pfam PF13405, EF-hand_6, 1 hit PF13499, EF-hand_7, 2 hits |
SMARTi | View protein in SMART SM00054, EFh, 5 hits |
SUPFAMi | SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 5 hits PS50222, EF_HAND_2, 5 hits |
i Sequence
Sequence statusi: Complete.
F1QUS0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANKAPEPIS LHLAELTASQ FLDIWNKFDA DGNGCIEGKE LENFIRELEI
60 70 80 90 100
ARKTADPSNA SFKDRMKEFM QKFDENGDGK IEMSELAQIL PTEENFLLCF
110 120 130 140 150
RQFVGSSAEF MTAWRKYDTD RSGYIESNEL KGFLSDLLKK ANRHYDDKKL
160 170 180 190 200
NEYTQTILKM FDLNGDGKLG LSEMARLLPV EENFLLKFQN FKLSAEEFEA
210 220 230 240 250
IFNYYDKDGN GYIDEHELDA LLRDLYHKHK MAVDPHSLSS SKKSIMALSD
260
GGKLFRTELE IVLCKDPSV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX510349 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000052802.5; ENSDARP00000052801.4; ENSDARG00000036344.5 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX510349 Genomic DNA No translation available. |
3D structure databases
AlphaFoldDBi | F1QUS0 |
SMRi | F1QUS0 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000052801 |
Proteomic databases
PaxDbi | F1QUS0 |
Genome annotation databases
Ensembli | ENSDART00000052802.5; ENSDARP00000052801.4; ENSDARG00000036344.5 |
Organism-specific databases
ZFINi | ZDB-GENE-040426-1668, calb2b |
Phylogenomic databases
eggNOGi | KOG0027, Eukaryota |
GeneTreei | ENSGT00950000183108 |
HOGENOMi | CLU_054826_1_1_1 |
InParanoidi | F1QUS0 |
OMAi | WSHYDRD |
PhylomeDBi | F1QUS0 |
TreeFami | TF325083 |
Gene expression databases
Bgeei | ENSDARG00000036344, Expressed in retina and 36 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR029646, CALB2 IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom |
PANTHERi | PTHR19972:SF4, PTHR19972:SF4, 1 hit |
Pfami | View protein in Pfam PF13405, EF-hand_6, 1 hit PF13499, EF-hand_7, 2 hits |
SMARTi | View protein in SMART SM00054, EFh, 5 hits |
SUPFAMi | SSF47473, SSF47473, 2 hits |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 5 hits PS50222, EF_HAND_2, 5 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | F1QUS0_DANRE | |
Accessioni | F1QUS0Primary (citable) accession number: F1QUS0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 3, 2011 | |
Last modified: | May 25, 2022 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |