UniProtKB - F1QT12 (F1QT12_DANRE)
Protein
Submitted name:
Collagen, type XV, alpha 1b
Gene
col15a1b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- extracellular matrix structural constituent Source: GO_Central
GO - Biological processi
- extracellular matrix organization Source: GO_Central
- eye development Source: ZFIN
- regulation of motor neuron axon guidance Source: ZFIN
Names & Taxonomyi
Protein namesi | Submitted name: Collagen, type XV, alpha 1bImported |
Gene namesi | Name:col15a1bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-070912-689, col15a1b |
Subcellular locationi
Extracellular region or secreted
- extracellular matrix Source: GO_Central
- extracellular space Source: GO_Central
Other locations
- collagen trimer Source: UniProtKB-KW
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 17 | Sequence analysisAdd BLAST | 17 | |
ChainiPRO_5003270251 | 18 – 1170 | Sequence analysisAdd BLAST | 1153 |
Proteomic databases
PaxDbi | F1QT12 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000061848, Expressed in camera-type eye and 65 other tissues |
ExpressionAtlasi | F1QT12, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 222 | LAM_G_DOMAINInterPro annotationAdd BLAST | 189 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 222 – 680 | DisorderedSequence analysisAdd BLAST | 459 | |
Regioni | 753 – 943 | DisorderedSequence analysisAdd BLAST | 191 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 223 – 238 | PolyampholyteSequence analysisAdd BLAST | 16 | |
Compositional biasi | 249 – 265 | PolyampholyteSequence analysisAdd BLAST | 17 | |
Compositional biasi | 302 – 322 | PolyampholyteSequence analysisAdd BLAST | 21 | |
Compositional biasi | 327 – 341 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 413 – 430 | Pro-richSequence analysisAdd BLAST | 18 | |
Compositional biasi | 455 – 481 | Pro-richSequence analysisAdd BLAST | 27 | |
Compositional biasi | 545 – 564 | Pro-richSequence analysisAdd BLAST | 20 | |
Compositional biasi | 597 – 613 | Pro-richSequence analysisAdd BLAST | 17 | |
Compositional biasi | 815 – 831 | Pro-richSequence analysisAdd BLAST | 17 | |
Compositional biasi | 882 – 909 | Pro-richSequence analysisAdd BLAST | 28 | |
Compositional biasi | 921 – 935 | Pro-richSequence analysisAdd BLAST | 15 |
Keywords - Domaini
CollagenARBA annotation, SignalSequence analysisPhylogenomic databases
eggNOGi | KOG3544, Eukaryota KOG3546, Eukaryota |
GeneTreei | ENSGT00940000164061 |
HOGENOMi | CLU_004003_1_0_1 |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR008160, Collagen IPR010515, Collagenase_NC10/endostatin IPR013320, ConA-like_dom_sf IPR016187, CTDL_fold IPR001791, Laminin_G |
Pfami | View protein in Pfam PF01391, Collagen, 5 hits PF06482, Endostatin, 1 hit |
SMARTi | View protein in SMART SM00210, TSPN, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56436, SSF56436, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
F1QT12-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKFRLLSWLV GAHLALGYLS SALHVMEERG SKGHLILTDL VGMPLPPSVS
60 70 80 90 100
FITGYEGYPA YSFGPHANVG RLTQSFVPEP FFTDFAIIVT VKPSSSRGGV
110 120 130 140 150
LFAITDPSQT IVQLGLALTP VEDQTQRIVL YYSEPRSANS AEVASFKVPD
160 170 180 190 200
MTQQWSRFTL SVERQEVRLY MDCDEYHIAP FKRSQQPLSF KPGSGIFVAN
210 220 230 240 250
AGSTGLERFV GSIQQLVIKP DPRAAEEQCE EDDPSLQASG DRSGDGDYDD
260 270 280 290 300
EEEHARREET FGQTNNKEKT LRPTSPVEAP PIQSPDIEEG GFSGHVTPID
310 320 330 340 350
ERLLRGTYKT DETGERVGQK GERGEPGPAG PPGPPGPPGT SVPIRHSGQP
360 370 380 390 400
GPRGPQGPIG QPGGRGRPGK DGQPGSKGED GKPGQRGQTG PPGLPGESGV
410 420 430 440 450
KGEKGDPGVG RTGLPGPPGP PGPPGPSKPV KVPYGFDALG SGFGDADIDT
460 470 480 490 500
ELLRGPPGPP GPPGIPGPPG PNSPLGGLLP GPPGAPGKDG RDGQSGLPGV
510 520 530 540 550
PGQDGLPGQQ GPKGAKGEHG IRGPPGPKGE NGDPGQRGPP GPFGTMGPRG
560 570 580 590 600
LPGPPGPPGP PGPINNNFMV DTLKDFEGSG ESGSFLGTGI LKGYQGPPGL
610 620 630 640 650
PGPPGPQGPP GANGPPGLSV KGERGSPGPD GIHGLAGLPG ARGPKGDKGN
660 670 680 690 700
PGEKGERGRD GLNITGPPGP PGPPGPIINF QDLFLNDTAA KLNLTKIRGL
710 720 730 740 750
PGPMGPEGLP GRAGFPGPRG PKGEIGFPGV QGPPGLKGDK GEPGVSIAAD
760 770 780 790 800
GSIITSLRGP RGPKGTKGDI GLAGPHGIPG PIGPPGLKGG YGIPGRPGRP
810 820 830 840 850
GIAGRKGDKG DASGPSGPPG PPGPPGPPGR VIGLNGGPKG DNGYNGQKGE
860 870 880 890 900
KGDPGLPGPP GLPGRTGLVG PKGESIVGPP GDTGAPGPPG LPGYGSPGPQ
910 920 930 940 950
GPPGAPGPPG TSSLYSSAAS LPGPPGPPGP PGAPGYGNPV STYKNSQTLM
960 970 980 990 1000
RESSQAAEGT MGYVIDKSEL YIRELKSFLP GYNLLPDTTH SMPALHLVAL
1010 1020 1030 1040 1050
NAPFSGDMHG IRGADYQCYQ QARARGLTST YRAFLSSHLQ DLSTIVKKAD
1060 1070 1080 1090 1100
RFNLPVVNLK GEVLFSSWMA MFSGNGGVFD PLTPIYSFDG RNVLTDQAWS
1110 1120 1130 1140 1150
QKLVWHGSST VGIRMTTNYC EAWRTGDMAV TGQASLLQTG RLLGQHTRSC
1160 1170
SNHFIILCIE NSYIQHPGRN
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF1QM25 | F1QM25_DANRE | Collagen, type XV, alpha 1b | col15a1b | 1,245 | Annotation score: | ||
A0A2R8QFF2 | A0A2R8QFF2_DANRE | Collagen, type XV, alpha 1b | col15a1b | 1,170 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX511097 Genomic DNA No translation available. CR788285 Genomic DNA No translation available. CU467838 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000137065; ENSDARP00000122740; ENSDARG00000061848 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX511097 Genomic DNA No translation available. CR788285 Genomic DNA No translation available. CU467838 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000122740 |
Proteomic databases
PaxDbi | F1QT12 |
Genome annotation databases
Ensembli | ENSDART00000137065; ENSDARP00000122740; ENSDARG00000061848 |
Organism-specific databases
ZFINi | ZDB-GENE-070912-689, col15a1b |
Phylogenomic databases
eggNOGi | KOG3544, Eukaryota KOG3546, Eukaryota |
GeneTreei | ENSGT00940000164061 |
HOGENOMi | CLU_004003_1_0_1 |
Gene expression databases
Bgeei | ENSDARG00000061848, Expressed in camera-type eye and 65 other tissues |
ExpressionAtlasi | F1QT12, baseline and differential |
Family and domain databases
CDDi | cd00247, Endostatin-like, 1 hit |
Gene3Di | 3.10.100.10, 1 hit |
InterProi | View protein in InterPro IPR016186, C-type_lectin-like/link_sf IPR008160, Collagen IPR010515, Collagenase_NC10/endostatin IPR013320, ConA-like_dom_sf IPR016187, CTDL_fold IPR001791, Laminin_G |
Pfami | View protein in Pfam PF01391, Collagen, 5 hits PF06482, Endostatin, 1 hit |
SMARTi | View protein in SMART SM00210, TSPN, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit SSF56436, SSF56436, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1QT12_DANRE | |
Accessioni | F1QT12Primary (citable) accession number: F1QT12 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 14, 2014 | |
Last modified: | October 7, 2020 | |
This is version 66 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |