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Protein

Cytochrome c heme lyase

Gene

hccsa.1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Links covalently the heme group to the apoprotein of cytochrome c.UniRule annotation

Catalytic activityi

Holocytochrome c = apocytochrome c + heme.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotation
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c heme lyaseUniRule annotation (EC:4.4.1.17UniRule annotation)
Gene namesi
Name:hccsa.1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-040718-202 hccsa.1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000028131 Expressed in 19 organ(s), highest expression level in muscle tissue

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000029466

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome c-type heme lyase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3996 Eukaryota
ENOG410YAUW LUCA
GeneTreeiENSGT00390000004175
KOiK01764
OMAiNEDTWRR
OrthoDBiEOG091G0JYQ
TreeFamiTF105185

Family and domain databases

InterProiView protein in InterPro
IPR000511 Cyt_C/C1_haem_lyase
PANTHERiPTHR12743 PTHR12743, 1 hit
PfamiView protein in Pfam
PF01265 Cyto_heme_lyase, 1 hit
PROSITEiView protein in PROSITE
PS00821 CYTO_HEME_LYASE_1, 1 hit
PS00822 CYTO_HEME_LYASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

F1QPK2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRDTMSSPTG TVKAEGIMVP DVGGAPPQGC PMHRNVNESV PPPECPMHQA
60 70 80 90 100
SRDHTKKAPD VPAHQDRAYE FVECPMRAAS GTKPTLSDIN PANMMPPPNQ
110 120 130 140 150
QPSADQPFPL SVVREESTIP RAGAEQNWVY PSEQMFWNAM LRKGWRWNKD
160 170 180 190 200
DINQNDMGDI IKIHNQNNEQ AWQEILRWEK LHSKECPCGP SLLRFGGKAK
210 220 230 240 250
DFSPRARFRY WMGHELPFDR HDWIVDRCGK EVRYVIDYYD GGLVSKHTIL
260 270
DVRPAFDSLG AVWDRMKVTW WRWTST
Length:276
Mass (Da):31,697
Last modified:May 3, 2011 - v1
Checksum:iB08D80F8F6ADF118
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR788249 Genomic DNA No translation available.
RefSeqiNP_001002498.2, NM_001002498.2
UniGeneiDr.34870

Genome annotation databases

EnsembliENSDART00000034865; ENSDARP00000029466; ENSDARG00000028131
ENSDART00000145974; ENSDARP00000117237; ENSDARG00000028131
ENSDART00000191478; ENSDARP00000147404; ENSDARG00000028131
GeneIDi436771
KEGGidre:436771

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR788249 Genomic DNA No translation available.
RefSeqiNP_001002498.2, NM_001002498.2
UniGeneiDr.34870

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000029466

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000034865; ENSDARP00000029466; ENSDARG00000028131
ENSDART00000145974; ENSDARP00000117237; ENSDARG00000028131
ENSDART00000191478; ENSDARP00000147404; ENSDARG00000028131
GeneIDi436771
KEGGidre:436771

Organism-specific databases

CTDi436771
ZFINiZDB-GENE-040718-202 hccsa.1

Phylogenomic databases

eggNOGiKOG3996 Eukaryota
ENOG410YAUW LUCA
GeneTreeiENSGT00390000004175
KOiK01764
OMAiNEDTWRR
OrthoDBiEOG091G0JYQ
TreeFamiTF105185

Gene expression databases

BgeeiENSDARG00000028131 Expressed in 19 organ(s), highest expression level in muscle tissue

Family and domain databases

InterProiView protein in InterPro
IPR000511 Cyt_C/C1_haem_lyase
PANTHERiPTHR12743 PTHR12743, 1 hit
PfamiView protein in Pfam
PF01265 Cyto_heme_lyase, 1 hit
PROSITEiView protein in PROSITE
PS00821 CYTO_HEME_LYASE_1, 1 hit
PS00822 CYTO_HEME_LYASE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1QPK2_DANRE
AccessioniPrimary (citable) accession number: F1QPK2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 12, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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