Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 85 (02 Jun 2021)
Sequence version 1 (03 May 2011)
Previous versions | rss
Add a publicationFeedback
Protein

HGF/SF receptor

Gene

met

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei1111ATPUniRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1205Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi1085 – 1093ATPUniRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, ReceptorARBA annotation, Transferase, Tyrosine-protein kinaseARBA annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-1257604, PIP3 activates AKT signaling
R-DRE-416550, Sema4D mediated inhibition of cell attachment and migration
R-DRE-5673001, RAF/MAP kinase cascade
R-DRE-6806942, MET Receptor Activation
R-DRE-6807004, Negative regulation of MET activity
R-DRE-6811558, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-DRE-8851805, MET activates RAS signaling
R-DRE-8851907, MET activates PI3K/AKT signaling
R-DRE-8874081, MET activates PTK2 signaling
R-DRE-8875555, MET activates RAP1 and RAC1
R-DRE-8875656, MET receptor recycling
R-DRE-8875791, MET activates STAT3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
HGF/SF receptorARBA annotation (EC:2.7.10.1ARBA annotation)
Alternative name(s):
Hepatocyte growth factor receptorARBA annotation
Proto-oncogene c-MetARBA annotation
Scatter factor receptorARBA annotation
Tyrosine-protein kinase MetARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:metImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 25

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-041014-1, met

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei932 – 954HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500995414625 – 1382HGF/SF receptorSequence analysisAdd BLAST1358

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1235Phosphotyrosine; by autocatalysisUniRule annotation1
Modified residuei1236Phosphotyrosine; by autocatalysisUniRule annotation1
Modified residuei1350Phosphotyrosine; by autocatalysisUniRule annotation1
Modified residuei1357Phosphotyrosine; by autocatalysisUniRule annotation1

Keywords - PTMi

Disulfide bondARBA annotation, GlycoproteinARBA annotation, Ubl conjugationARBA annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1QLR7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000070903, Expressed in lateral line primordium and 72 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000123904

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 510SemaInterPro annotationAdd BLAST484
Domaini1079 – 1342Protein kinaseInterPro annotationAdd BLAST264

Keywords - Domaini

RepeatARBA annotation, SignalSequence analysisARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1095, Eukaryota
KOG3610, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158022

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005158_0_0_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
DEEPGQC

Database of Orthologous Groups

More...
OrthoDBi
408584at2759

TreeFam database of animal gene trees

More...
TreeFami
TF317402

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 1 hit
2.60.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR011009, Kinase-like_dom_sf
IPR031148, Plexin
IPR002165, Plexin_repeat
IPR000719, Prot_kinase_dom
IPR017441, Protein_kinase_ATP_BS
IPR016201, PSI
IPR001627, Semap_dom
IPR036352, Semap_dom_sf
IPR001245, Ser-Thr/Tyr_kinase_cat_dom
IPR008266, Tyr_kinase_AS
IPR020635, Tyr_kinase_cat_dom
IPR016244, Tyr_kinase_HGF/MSP_rcpt
IPR015943, WD40/YVTN_repeat-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR22625, PTHR22625, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07714, PK_Tyr_Ser-Thr, 1 hit
PF01437, PSI, 1 hit
PF01403, Sema, 1 hit
PF01833, TIG, 3 hits

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000617, TyrPK_HGF-R, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00109, TYRKINASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00429, IPT, 4 hits
SM00423, PSI, 1 hit
SM00630, Sema, 1 hit
SM00219, TyrKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101912, SSF101912, 1 hit
SSF56112, SSF56112, 1 hit
SSF81296, SSF81296, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00107, PROTEIN_KINASE_ATP, 1 hit
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00109, PROTEIN_KINASE_TYR, 1 hit
PS51004, SEMA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1QLR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIHYSEAAS ILIILQSLWW GLNCQCEEPI ESSKLDLSVT YDLPYFVSDT
60 70 80 90 100
PIQKLLEING TVYVGAVNRL YALSKDLKKK HEYKTGPVHE GPDCKTPTDQ
110 120 130 140 150
CSGCENKPRN INNTNMALLM ETFYDLELFS CGSVGNGVCS RHVLEDGPLG
160 170 180 190 200
AEVTCMYTKK NEGSSHGCPD CLAGPAGTQI LNIMSGRVVR FFVANSEPLE
210 220 230 240 250
SNGPRLHHTI SIRKMRETQD GFEFFSDQSY MDLAPSLRGN YPLHYVYSFQ
260 270 280 290 300
SGPYVYFLTV QREGGNSKAF HTRIVRMCSS DSEILRYVEM PFECIYSERR
310 320 330 340 350
RKKRSAQVVF NVLQAAHVAK VGYDFQQEMG LKEGEDVLFA AFARSKPDSP
360 370 380 390 400
EPTASSAVCL ISITDINEFF KVFIQKGYTR KLHHFPGSEE KTFNQTFVGD
410 420 430 440 450
SFSCGKHERG YRLEVTSTNP RRDYFHGRFR NVLLTSIAVV PIQNHTVVSL
460 470 480 490 500
GTAEGRVIQV VVSRFGKTEP HVDFRLDTLP VSSEMALLSP QHHNGSLLLI
510 520 530 540 550
TGNKVSKLPV IGPGCEQLWT CSSCLLAPGF MGCGWCRTSN LCTRAPRCPQ
560 570 580 590 600
SQWIQDSCPL LITSISPSSA PLRGQTNITI CGKNFGFNKK DRFDTKLIDV
610 620 630 640 650
VVAGTKCKLE RKDSNNNRLV CGLDHVNWSS VDSVVTVRSG KEQAQKDGFS
660 670 680 690 700
FVNPVIIEIF PEFGPQSGGT MLTISGSFLD SGNVQTVTVG NATCVLQSVS
710 720 730 740 750
ATMLTCRTPP QPSPSQHKVQ LHIDGVIFEA PVSYTYNKNP HISSVQPKHS
760 770 780 790 800
FISGGSTVTV NGFYLHSALQ PQMVLTAATE GKLFQVTCSH DEDKRNILCI
810 820 830 840 850
TPSLKGLSVQ PPVATKMTFV LDGFSTDQYD LLYVEDPKFE EFQKPTVTPR
860 870 880 890 900
GKKNILEIKV PPVNQEAVKN GEVLRVSNRT CESVTLVGNT LECTVPMELQ
910 920 930 940 950
TAAKELEVEW KQATSSVILG RVILAQDQDY RILITGGVCV SILLLLLIAV
960 970 980 990 1000
FVWIKRKKHI NDLAKTMVWY DGRAHIPHLD MLANARSVSP TNEMVSHESV
1010 1020 1030 1040 1050
DYRTTLLEDQ NLPLSQTESC RPHLYAHSHV DLSPMLGPME GDLASPLLPS
1060 1070 1080 1090 1100
TAPIDLGSLH PELLKEVQHV VIAREDLLLH VNEIIGRGHF GCVFHGTLLE
1110 1120 1130 1140 1150
PDGQKQHCAI KSLNRITDIE EVSQFLKEGI IMKDFSHPNV LSLLGICLPS
1160 1170 1180 1190 1200
EGSPLVVLPY MKHGDLRNFI RDESHNPTVK DLMGFGLQVA KGMEYLASKK
1210 1220 1230 1240 1250
FVHRDLAARN CMLDESYTVK VADFGLARDV YDKEYYSVHN KHGVKLPVKW
1260 1270 1280 1290 1300
MALESLQTHK FTTKSDVWSF GVLLWELMTR GAPPYSDVNS FDITVFLLQG
1310 1320 1330 1340 1350
RRLLQPEFCP DALYNVMIEC WHPKPERRPT FSELVSRISA IFSSFSGEHY
1360 1370 1380
ILLNTTYVNI DKMTPYPSLI SSQSNLDRDC CT
Length:1,382
Mass (Da):154,185
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB8BB057D013476C2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR848711 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_005163051.1, XM_005162994.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000148741; ENSDARP00000123904; ENSDARG00000070903
ENSDART00000180287; ENSDARP00000152967; ENSDARG00000070903

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100150664

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848711 Genomic DNA No translation available.
RefSeqiXP_005163051.1, XM_005162994.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000123904

Proteomic databases

PaxDbiF1QLR7

Genome annotation databases

EnsembliENSDART00000148741; ENSDARP00000123904; ENSDARG00000070903
ENSDART00000180287; ENSDARP00000152967; ENSDARG00000070903
GeneIDi100150664

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4233
ZFINiZDB-GENE-041014-1, met

Phylogenomic databases

eggNOGiKOG1095, Eukaryota
KOG3610, Eukaryota
GeneTreeiENSGT00940000158022
HOGENOMiCLU_005158_0_0_1
OMAiDEEPGQC
OrthoDBi408584at2759
TreeFamiTF317402

Enzyme and pathway databases

ReactomeiR-DRE-1257604, PIP3 activates AKT signaling
R-DRE-416550, Sema4D mediated inhibition of cell attachment and migration
R-DRE-5673001, RAF/MAP kinase cascade
R-DRE-6806942, MET Receptor Activation
R-DRE-6807004, Negative regulation of MET activity
R-DRE-6811558, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-DRE-8851805, MET activates RAS signaling
R-DRE-8851907, MET activates PI3K/AKT signaling
R-DRE-8874081, MET activates PTK2 signaling
R-DRE-8875555, MET activates RAP1 and RAC1
R-DRE-8875656, MET receptor recycling
R-DRE-8875791, MET activates STAT3

Gene expression databases

BgeeiENSDARG00000070903, Expressed in lateral line primordium and 72 other tissues

Family and domain databases

Gene3Di2.130.10.10, 1 hit
2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR011009, Kinase-like_dom_sf
IPR031148, Plexin
IPR002165, Plexin_repeat
IPR000719, Prot_kinase_dom
IPR017441, Protein_kinase_ATP_BS
IPR016201, PSI
IPR001627, Semap_dom
IPR036352, Semap_dom_sf
IPR001245, Ser-Thr/Tyr_kinase_cat_dom
IPR008266, Tyr_kinase_AS
IPR020635, Tyr_kinase_cat_dom
IPR016244, Tyr_kinase_HGF/MSP_rcpt
IPR015943, WD40/YVTN_repeat-like_dom_sf
PANTHERiPTHR22625, PTHR22625, 1 hit
PfamiView protein in Pfam
PF07714, PK_Tyr_Ser-Thr, 1 hit
PF01437, PSI, 1 hit
PF01403, Sema, 1 hit
PF01833, TIG, 3 hits
PIRSFiPIRSF000617, TyrPK_HGF-R, 1 hit
PRINTSiPR00109, TYRKINASE
SMARTiView protein in SMART
SM00429, IPT, 4 hits
SM00423, PSI, 1 hit
SM00630, Sema, 1 hit
SM00219, TyrKc, 1 hit
SUPFAMiSSF101912, SSF101912, 1 hit
SSF56112, SSF56112, 1 hit
SSF81296, SSF81296, 3 hits
PROSITEiView protein in PROSITE
PS00107, PROTEIN_KINASE_ATP, 1 hit
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00109, PROTEIN_KINASE_TYR, 1 hit
PS51004, SEMA, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1QLR7_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1QLR7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 2, 2021
This is version 85 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again