Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Due to a server migration, the UniProt 'ID mapping', 'Peptide search' and 'community bibliography submission' tools will not be available on the 19th April 2021 during the morning (EST).
Entry version 69 (02 Dec 2020)
Sequence version 1 (03 May 2011)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Ankyrin repeat and BTB (POZ) domain-containing 2b

Gene

abtb2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin repeat and BTB (POZ) domain-containing 2bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:abtb2bImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 25

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-100422-14, abtb2b

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1QLH2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000062000, Expressed in pharyngeal gill and 20 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000083546

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini505 – 628ANK_REP_REGIONInterPro annotationAdd BLAST124
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati511 – 543ANKPROSITE-ProRule annotationAdd BLAST33
Repeati596 – 628ANKPROSITE-ProRule annotationAdd BLAST33
Domaini850 – 919BTBInterPro annotationAdd BLAST70

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni683 – 703DisorderedSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QSQY, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157661

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001918_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1QLH2

Identification of Orthologs from Complete Genome Data

More...
OMAi
HRGIMPA

Database of Orthologous Groups

More...
OrthoDBi
416322at2759

TreeFam database of animal gene trees

More...
TreeFami
TF106437

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.20.10, 1 hit
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR000210, BTB/POZ_dom
IPR009072, Histone-fold
IPR011333, SKP1/BTB/POZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 1 hit
PF00651, BTB, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 4 hits
SM00225, BTB, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47113, SSF47113, 2 hits
SSF48403, SSF48403, 1 hit
SSF54695, SSF54695, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50097, BTB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1QLH2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGTNSSNMK TLEDLTLDSG YGAGDSCKSL SLSSSKSNSQ AFMNTPHRGN
60 70 80 90 100
WWYYSGSMNS RNNSWDTVNT VLPEDPEDIF SKCPRLPELE EFPWTEEDVG
110 120 130 140 150
RVVRKGAGKG ASFSAEAVRR LATLMRRALI RISREAQRLS VMHCRCTKFE
160 170 180 190 200
VQSAIRLVLS WALADHCVSA TVKAISMYNM SAGELLRKGK SARCGLVFSV
210 220 230 240 250
GRFFRWMVDT RIAVRIHEYA AICLSACMEA LVEEVGVRIL MAEREGATPG
260 270 280 290 300
CVLTAETLEG VINNDAELWG VLQHHEHLIC GKNANGVLSL PAHFSPYTEG
310 320 330 340 350
RQTGLETRED AYAELELRTL EQALLATCVG SISELSDLVS RAMHHMQRLS
360 370 380 390 400
SVRHGLSPAR HARQQPVSWS PDALHTLYYF LRCPQMESME NPNLDPPRMA
410 420 430 440 450
LSKERPFLLL PPLMEWMRVA IVHAEHRRSL LVDSDDVRQT ARLLLPGLDC
460 470 480 490 500
EPRLLKPECC FSSFRRLDAK AATDKFQLDL GFRMLNCGRT DLIGQAIELL
510 520 530 540 550
GPDGVNSMDD QGMTPLMYAC SAGDEALVQM LIDAGANLDV AVPMCSPKHP
560 570 580 590 600
SVHADSRHWV ALTFAVLHGH ISVAQLLLDA GANVEGAAIR YGQENTSETP
610 620 630 640 650
LQLASAAGNY EMVSLLLARG ADPLLRSQDS NTLTSSLYED MNCFSHAAAH
660 670 680 690 700
GHRNVLRKLL SQPQKVREDV LSLEEILAEG VDGETQASGR NGHSLPPPPS
710 720 730 740 750
PNLSLVSEDA LPKLCKTRMK ALQEASFYSA EHGYLDVTME LRSLGVPWKL
760 770 780 790 800
HVWLESLRSA QQKSRAGVML SLLRDFTSVK EEDYCEELVS VGLPLMFNIL
810 820 830 840 850
KNSKNEAIIQ QLGIIFSHCY GTAPLPPIQE KKAALAAQLD PHFLNNQEMS
860 870 880 890 900
DVTFLVEGKP FYAHGVLLLT ASDRFKTLLA QNGSDSTQTR KDIEISNIKY
910 920 930 940 950
NIFQMMMSYL YCGGTESLKM GVSELLELLS AASLFQLGVL QRHCEILCAQ
960 970 980 990 1000
NIDLDNAVNI YHTAKANGAV ELSTYCEGYF LQNMAVLLER EAFRVMILGS
1010 1020 1030
GARSGSGKDS LLEALEATLV RRLRSLLVTS RV
Length:1,032
Mass (Da):114,051
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFBDC1F3CC59E1AB7
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR854832 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_001923186.1, XM_001923151.5
XP_009296329.1, XM_009298054.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000089113; ENSDARP00000083546; ENSDARG00000062000

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100007078

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:100007078

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR854832 Genomic DNA No translation available.
RefSeqiXP_001923186.1, XM_001923151.5
XP_009296329.1, XM_009298054.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000083546

Proteomic databases

PaxDbiF1QLH2

Genome annotation databases

EnsembliENSDART00000089113; ENSDARP00000083546; ENSDARG00000062000
GeneIDi100007078
KEGGidre:100007078

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
100007078
ZFINiZDB-GENE-100422-14, abtb2b

Phylogenomic databases

eggNOGiENOG502QSQY, Eukaryota
GeneTreeiENSGT00940000157661
HOGENOMiCLU_001918_0_0_1
InParanoidiF1QLH2
OMAiHRGIMPA
OrthoDBi416322at2759
TreeFamiTF106437

Gene expression databases

BgeeiENSDARG00000062000, Expressed in pharyngeal gill and 20 other tissues

Family and domain databases

Gene3Di1.10.20.10, 1 hit
1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR000210, BTB/POZ_dom
IPR009072, Histone-fold
IPR011333, SKP1/BTB/POZ_sf
PfamiView protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 1 hit
PF00651, BTB, 1 hit
SMARTiView protein in SMART
SM00248, ANK, 4 hits
SM00225, BTB, 1 hit
SUPFAMiSSF47113, SSF47113, 2 hits
SSF48403, SSF48403, 1 hit
SSF54695, SSF54695, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50097, BTB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1QLH2_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1QLH2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: December 2, 2020
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again