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Entry version 68 (31 Jul 2019)
Sequence version 2 (20 Jan 2016)
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Protein
Submitted name:

Filamin C, gamma b (actin-binding protein 280)

Gene

flncb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingSAAS annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-446353 Cell-extracellular matrix interactions

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Filamin C, gamma b (actin-binding protein 280)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:flncbImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-041008-175 flncb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1QL44

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000018820 Expressed in 32 organ(s), highest expression level in tail bud paraxial mesoderm

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000024947

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini45 – 151Calponin-homology (CH)InterPro annotationAdd BLAST107
Domaini168 – 271Calponin-homology (CH)InterPro annotationAdd BLAST104
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati279 – 377FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati379 – 477FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati519 – 615FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati616 – 708FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati712 – 808FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati809 – 911FilaminPROSITE-ProRule annotationAdd BLAST103
Repeati912 – 1010FilaminPROSITE-ProRule annotationAdd BLAST99
Repeati1011 – 1106FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1107 – 1199FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1200 – 1294FilaminPROSITE-ProRule annotationAdd BLAST95
Repeati1295 – 1394FilaminPROSITE-ProRule annotationAdd BLAST100
Repeati1395 – 1487FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1488 – 1583FilaminPROSITE-ProRule annotationAdd BLAST96
Repeati1584 – 1680FilaminPROSITE-ProRule annotationAdd BLAST97
Repeati1693 – 1784FilaminPROSITE-ProRule annotationAdd BLAST92
Repeati1833 – 1902FilaminPROSITE-ProRule annotationAdd BLAST70
Repeati1902 – 1994FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati1992 – 2081FilaminPROSITE-ProRule annotationAdd BLAST90
Repeati2084 – 2176FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati2251 – 2355FilaminPROSITE-ProRule annotationAdd BLAST105
Repeati2358 – 2450FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati2452 – 2545FilaminPROSITE-ProRule annotationAdd BLAST94
Repeati2549 – 2641FilaminPROSITE-ProRule annotationAdd BLAST93
Repeati2678 – 2772FilaminPROSITE-ProRule annotationAdd BLAST95

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 39DisorderedSequence analysisAdd BLAST39
Regioni484 – 532DisorderedSequence analysisAdd BLAST49
Regioni2230 – 2315DisorderedSequence analysisAdd BLAST86

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 18PolarSequence analysisAdd BLAST18
Compositional biasi505 – 521Pro-richSequence analysisAdd BLAST17
Compositional biasi2231 – 2258PolyampholyteSequence analysisAdd BLAST28
Compositional biasi2282 – 2311PolarSequence analysisAdd BLAST30

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0518 Eukaryota
COG5069 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153588

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1QL44

KEGG Orthology (KO)

More...
KOi
K04437

Identification of Orthologs from Complete Genome Data

More...
OMAi
YPTHWAT

Database of Orthologous Groups

More...
OrthoDBi
35998at2759

TreeFam database of animal gene trees

More...
TreeFami
TF313685

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014 CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits
2.60.40.10, 24 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307 CH, 2 hits
PF00630 Filamin, 23 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033 CH, 2 hits
SM00557 IG_FLMN, 24 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576 SSF47576, 1 hit
SSF81296 SSF81296, 24 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS50194 FILAMIN_REPEAT, 24 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1QL44-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMSNNTYYDQ QLPPQYYQGT DNGEDGDEEM PATEKDLAED APWKKIQQNT
60 70 80 90 100
FTRWCNEHLK CLNRKILDLQ KDLTDGLKLI GLLEVLSQKK MYRKYHARPN
110 120 130 140 150
FRQMKLENVS VALEFLEREH IKLVSIDSKA IVDGNLKLIL GLIWTLILHY
160 170 180 190 200
SISMPMWEDE DDEDARKLTP KQRLLGWIQN KVPQLHINNF HRDWRDGKAL
210 220 230 240 250
GALVDNCAPG LCPDWETWDP SQPVENAREA MQQADDWLGV PQVIAPEEIV
260 270 280 290 300
DPNVDEHSVM TYLSQFPKAK LKPGAPLRPK TLHPKRAKAY GPGIEPRGNV
310 320 330 340 350
VLKPAEFVVE TVEAGLGEVL VYIEDPEGHT EEARVIPNND RNRSYSVVYV
360 370 380 390 400
PKVEGLHKVK VLFAGQDIDR SPFLVNVSKA LGDPNKVQAR GPGLEPVGNV
410 420 430 440 450
ANKPTYFDIY TAGAGAGDVG VIIVDSQGRR DTVEIILENK GDSVFRCTYG
460 470 480 490 500
PILEGPHTIY VTFAGQQIPR SPFTVHISEA PPHGRQIGSP VHIIPQSLRT
510 520 530 540 550
PPSEKAKKVP PPTPPKPRRP TSNPNACRAI GRGLQPKGVR VKEVADFKVY
560 570 580 590 600
TKGAGSGELR VHVKGPTGGD EPVKVEDLGD GVYECDYYPI FCGKYIITVT
610 620 630 640 650
WGGHAIPRSP FEVIISEDAG PQKVRAWGPG LETGMVGKSA DFVVEAIGTE
660 670 680 690 700
VGTLGFSIEG PSQAKIECDD KGDGSCDVLY WPTEPGDYAV HVICDDEDIK
710 720 730 740 750
DSPFMAHILP AASDVFPEKV KCYGPGLEPT GCIVNKPAEF TIDARGAGRG
760 770 780 790 800
QLQIYAQDSE GFPINIQITD NGDSTYFCVY IPIKPIKHTI IITWGEVNVP
810 820 830 840 850
NSPFRVTIGE GSHPENVKVH GPGVEKTGLK ANEPTYFTVD CSEAGQGDVS
860 870 880 890 900
IGIKCAPGVV GPAEADIDFD IIKNDNDTFT VKYTPPGAGR YTIMVLFADQ
910 920 930 940 950
EIPISPFRIK VDPSHDANKV KAEGPGLNKT GVEVGKPTHF TIYTKGAGKA
960 970 980 990 1000
TPEVHFTASG RGDAVSDFEI IDNHDYSFTV RYTALQQGNM TISVCHGGDP
1010 1020 1030 1040 1050
IPKSPFTISV APPLDLNKVK VHGLNNKVDV GKDEEFTVNT RGAGGQGKVD
1060 1070 1080 1090 1100
VKITSPSRRP IPCKVESGAS NEVHTVKYIP PEEGPYKVDI SYDGNPVPGS
1110 1120 1130 1140 1150
PFTVEGVMPP DPSKVRAYGP GLKGGIVGKP APFAIDTKGA GTGGLGLTVE
1160 1170 1180 1190 1200
GPCEAKIECQ DNGDGSCSVS YLPTEPGEYS INILFADAHI PGSPFKAMVQ
1210 1220 1230 1240 1250
SVFDPSKVTA SGPGLERGKV NEAGSFTVDC SKAGEAELTI EIISDSGAQA
1260 1270 1280 1290 1300
EVHVQNNSDG TYSITYIPPF HGMYTITIKY GGHAVPKFPA RVQVDPALDT
1310 1320 1330 1340 1350
SGIKVYGPGV EPRGVLREVT THFIVDTRVH NKMGGNHIKV RIVNPSGANT
1360 1370 1380 1390 1400
DAYVTDKADG TYRVEYTAYE DGVHLIEVLY DDVPVPKSPF RVAVAEGCDP
1410 1420 1430 1440 1450
SRVRAYGPGL EEGLVNKPNR FTVETRGAGT GGLGLAIEGP SEAKMSCKDN
1460 1470 1480 1490 1500
KDGSCSVEYI PFTPGEYDVN ITFGGLPIPG SPFRVPVREL VDPSKVKCTG
1510 1520 1530 1540 1550
PGLGSGVRAH VPQTFTVDCS KAGLAPLEVL LYGPTGMTEP VNITDNGDGT
1560 1570 1580 1590 1600
HTVVYTPAKD GPYTVCVKYA DQEVPRSPFK IKVLPAHDAS KVRASGPGLN
1610 1620 1630 1640 1650
ASGVPASLPV EFTIDARDAG EGLLTVQILD PEGKPKKANI RDNRDGTYTV
1660 1670 1680 1690 1700
SYVPDMTGRY TITIKYGGDE IPYSPYRIHA LPSGDASKCL VTVSIGGHGL
1710 1720 1730 1740 1750
GSGLGPTIQI GEETVITVDA KAAGKGKVTC KVSTPDGAEL DVDVVENADG
1760 1770 1780 1790 1800
TFDIYYTAPE PGKYVITIRF GGEHIPNSPF HVVASDTIPI IEEPCDKLQL
1810 1820 1830 1840 1850
QQPYAPYQGY SPHWATEEPV TAVDIIEPVL RPFNLVIPFT VQKGEITGEV
1860 1870 1880 1890 1900
HMPSGKTASP HITDNKDGTV TVKYAPTEKG LHEMDIKYDG NHIPGSPLQF
1910 1920 1930 1940 1950
YVDAINSGHV NAYGPGLSHG MVNKSATFTI VTKDAGEGGL SLAVEGPSKA
1960 1970 1980 1990 2000
EISCKDNKDG TCTVSYLPTA PGDYNIIVKF DDKHIAGSPF TAKITGDDSM
2010 2020 2030 2040 2050
RTSQLNVGTA TDVSLKITET DLSSLSATIR APSGNEEPCL LKRLPNRHIG
2060 2070 2080 2090 2100
ISFTPKEVGE HVVSVKKNGK HVTNSPFKIM VGQSEIGDAS KVKVSGKGLI
2110 2120 2130 2140 2150
EGHTFEVAEF IVDTRSAGYG GLGLSIEGPS KVDINCSDVD DGTCKVTYCP
2160 2170 2180 2190 2200
TEPGTYIINI KFADQHVPGS PFTVKVLGEG RMKESITRKR QAPSIATVGS
2210 2220 2230 2240 2250
TCDLNLKIPG NWFQMVSAQE RLTRTFTRSS HTYTRTERTE ISKTRAGETK
2260 2270 2280 2290 2300
REVRVEESTQ VGGDPFRDVF GGFMGRESLG PFNSPQGRQS EGESGTQEMT
2310 2320 2330 2340 2350
AQVTSPSGNT EDAEIIEGED STYSVRFVPH EMGPHTVNVK YRGQHVPGSP
2360 2370 2380 2390 2400
FQFTVGPLGE GGAHKVRAGG TGLDRGVAGV PAEFSIWTRE AGAGGLSIAV
2410 2420 2430 2440 2450
EGPSKAEISF EDRKDGSCGV AYIVQEPGDY EVSIKFNDEH IPDSPFIVPI
2460 2470 2480 2490 2500
ASLSDDARLL TVTSLQEMGL KVNQEASFAV QLNGARGAID AKVHTPSGAV
2510 2520 2530 2540 2550
EECYITELDN DKHAIRFIPR ENGVHSIDVR FNGSHIPGSP FKIRVGEPGQ
2560 2570 2580 2590 2600
AGDPGMVTAF GPGLEGGTTG VPSDFIVNTC NAGSGALSVT IDGPSKVKMD
2610 2620 2630 2640 2650
CQECPEGYKV TYTPMAPGSY LISIKYGGPQ HIVGSPFKAK VSGARLSGGH
2660 2670 2680 2690 2700
SLHETSSVLV ETVTKSSSVA GSFSTLPKFS SDASKVVSRG AGLSKAFIGQ
2710 2720 2730 2740 2750
KNTFTVDCSK AGTNMLMVGV HGPKTPCEEV YVKHMGNRMY NVTYTVKEKG
2760 2770
DYILIVKWGE EMVPGSPFHV TVP
Length:2,773
Mass (Da):297,889
Last modified:January 20, 2016 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i32865ABF7CEA3D46
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX470230 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_009298480.1, XM_009300205.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000026492; ENSDARP00000024947; ENSDARG00000018820

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
570288

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:570288

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX470230 Genomic DNA No translation available.
RefSeqiXP_009298480.1, XM_009300205.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000024947

Proteomic databases

PaxDbiF1QL44

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000026492; ENSDARP00000024947; ENSDARG00000018820
GeneIDi570288
KEGGidre:570288

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
570288
ZFINiZDB-GENE-041008-175 flncb

Phylogenomic databases

eggNOGiKOG0518 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00940000153588
InParanoidiF1QL44
KOiK04437
OMAiYPTHWAT
OrthoDBi35998at2759
TreeFamiTF313685

Enzyme and pathway databases

ReactomeiR-DRE-446353 Cell-extracellular matrix interactions

Gene expression databases

BgeeiENSDARG00000018820 Expressed in 32 organ(s), highest expression level in tail bud paraxial mesoderm

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 2 hits
2.60.40.10, 24 hits
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF00630 Filamin, 23 hits
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00557 IG_FLMN, 24 hits
SUPFAMiSSF47576 SSF47576, 1 hit
SSF81296 SSF81296, 24 hits
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits
PS50194 FILAMIN_REPEAT, 24 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1QL44_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1QL44
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: January 20, 2016
Last modified: July 31, 2019
This is version 68 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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