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UniProtKB - F1QI87 (F1QI87_DANRE)

Entry version 71 (25 May 2022)
Sequence version 1 (03 May 2011)
Previous versions | rss
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Protein
Submitted name:

Gon-4-like (C. elegans)

Gene

gon4lb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Gon-4-like (C. elegans)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gon4lbImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Zebrafish Information Network genome database

More...ZFINi		ZDB-GENE-070117-2447, gon4lb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F1QI87

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSDARG00000005867, Expressed in blastula and 32 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7955.ENSDARP00000109415

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		F1QI87

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		F1QI87

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 93DisorderedSequence analysisAdd BLAST93
Regioni253 – 314DisorderedSequence analysisAdd BLAST62
Regioni496 – 523DisorderedSequence analysisAdd BLAST28
Regioni1100 – 1145DisorderedSequence analysisAdd BLAST46
Regioni1209 – 1245DisorderedSequence analysisAdd BLAST37
Regioni1265 – 1550DisorderedSequence analysisAdd BLAST286
Regioni1841 – 1965DisorderedSequence analysisAdd BLAST125
Regioni2031 – 2055DisorderedSequence analysisAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili142 – 162Sequence analysisAdd BLAST21
Coiled coili545 – 565Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi24 – 66Polar residuesSequence analysisAdd BLAST43
Compositional biasi74 – 89Polar residuesSequence analysisAdd BLAST16
Compositional biasi254 – 280Acidic residuesSequence analysisAdd BLAST27
Compositional biasi281 – 296Polar residuesSequence analysisAdd BLAST16
Compositional biasi504 – 519Acidic residuesSequence analysisAdd BLAST16
Compositional biasi1209 – 1229Polar residuesSequence analysisAdd BLAST21
Compositional biasi1265 – 1281Polar residuesSequence analysisAdd BLAST17
Compositional biasi1312 – 1326Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1334 – 1389Basic and acidic residuesSequence analysisAdd BLAST56
Compositional biasi1390 – 1416Acidic residuesSequence analysisAdd BLAST27
Compositional biasi1436 – 1453Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1454 – 1477Polar residuesSequence analysisAdd BLAST24
Compositional biasi1492 – 1509Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1856 – 1945Basic and acidic residuesSequence analysisAdd BLAST90

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502QT2W, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164105

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000833_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F1QI87

Identification of Orthologs from Complete Genome Data

More...OMAi		HRNYKDC

Database of Orthologous Groups

More...OrthoDBi		49443at2759

TreeFam database of animal gene trees

More...TreeFami		TF343327

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1160.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR009057, Homeobox-like_sf
IPR003822, PAH
IPR036600, PAH_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02671, PAH, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46689, SSF46689, 1 hit
SSF47762, SSF47762, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51477, PAH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1QI87-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGWKRKSSSP EPQPNLVKLP KRESLSRSPS SWKRKASTPS KTKSWTSIQS 
        60         70         80         90        100
LSPDRHVDQC NGQEKMSSAG HVEDDSDCIQ SSTPVSSPLR SEEDAELGLV 
       110        120        130        140        150
ITVDEDRCEG EEWLKKRNGV NIKKNGINQT EGEIPQKEDG DVEKTMEQLS 
       160        170        180        190        200
EEDENEEELR KLDRDLTLKS KKLNLSSINV RNIIHEVVTN EHVVAMMKAA 
       210        220        230        240        250
IKETQDMPMF EPKMTRSKLK EAVEKGVGMG NWNISPIKKA NDIKPPQFVD 
       260        270        280        290        300
IPLQEEEDSS DEEYCPDEDE EDETAEETFL ESDVESTSSS PRGIRRFPSQ 
       310        320        330        340        350
TPPHCDDASN SPRLKPRLAR HLRVEAVPMG PPAPPPQSCG LSRSLKTLDP 
       360        370        380        390        400
FIEKLHAVDK ELELSPLCME PYQALSSGGA GEPDDSLVAC RTRSKRPLRD 
       410        420        430        440        450
VPLDQLEAEL RAPDITPDMY DNVSTPEDRE WTQWLQGLMT SHLDNDEEAD 
       460        470        480        490        500
EDDDPEYNFL DDLDEPDLED YRNDRAVRIT KKEVNELMEE LFETFHDELA 
       510        520        530        540        550
ANEPDDEGHD EDEEREEEAN DTPQFNVPQA IRFEEPLAHM LTACRRTVRE 
       560        570        580        590        600
QLDALQQRRE NQVRTTQHAS GPGMVFVQPS CPLVVTPAQR IQLQQQIQQH 
       610        620        630        640        650
VQLLTQVSML CDPVGALQTE AQTTKHFLGE LLSFAERAEE ERSAVNLGFK 
       660        670        680        690        700
SVFRVCNLLS SINLLEEVKQ SPSLSCLPPK PNRHHSVHSY PLLPAGLAWL 
       710        720        730        740        750
FATRSVFLYP ELLPHCSLDP ALHPSRSKHY YSKGEDGLLV LGLKHFAQTE 
       760        770        780        790        800
FPYQLISRYL IRPKRQEQLR MRVKDMVSPK YPHNIIKYYC QNHVVPPLPV 
       810        820        830        840        850
VCKPVVHGEE RPPVEREQEV MPNWLKKSLP LIQKSICQSD LTMTSTTKSA 
       860        870        880        890        900
SLPFPKETRY PQFLPKGLSL RLHPSQVASR PSQPKSRILR AFTNRTLAPL 
       910        920        930        940        950
AKAPSCPTGT GHLLTNISTP VLLLAQAPST PINGVFPLVH PSLTPAHGTV 
       960        970        980        990       1000
PLNASYPINF HYLSPELGAS NPAHLPANLP PSVVQKPQCD VPLLSTGTVK 
      1010       1020       1030       1040       1050
THGVQQQTSD KHKKRTMPRK LAPLRPAPQL PRLLPLSSGS IGNISNPGII 
      1060       1070       1080       1090       1100
IDQQISLNVP HNLQSDNVIV IKAHENVNTH RTVPSLSPDL VVQLVPQTQV 
      1110       1120       1130       1140       1150
AENTTSSLPR KTTPRSDVSQ TAKDIPSVQS SGENGQRTVF SPQTAAPAAV 
      1160       1170       1180       1190       1200
DSSQFVLVQT VSPTGPPQFL LLPQDSLVLN QPASLPSEGT LQNLSQQTSH 
      1210       1220       1230       1240       1250
LDISTTSTAL KNSEKTEVHL NNPTTSLPVS REEDGERQEV DEEMVGDRWE 
      1260       1270       1280       1290       1300
EEMASALFGS PLLALSESSC SPDSSPDASM DSGSDAMVRV EMEDGELPSV 
      1310       1320       1330       1340       1350
HSASATQETP DVHKHSSGDE KEQQSSGGEK QNSGNEEGRA EESESRKDEA 
      1360       1370       1380       1390       1400
QDEDKGGEKN EDGEGDGKRD EGGSGDKGRE EKDGDGEKDG DGERDEEEED 
      1410       1420       1430       1440       1450
FDDLTQDEDE EEVMSSASEE SVLSVPELQE TMEKLTWLAS ERRLCREGDS 
      1460       1470       1480       1490       1500
EEDNSPTSPT SPTSPNSQNS PASQNSQEEN SEDEDDGAMK GDELEAGEGE 
      1510       1520       1530       1540       1550
GEKLPEGDAP AGDDPPQISE KVGGRGRGRG RPPPRSLKRG RRQERGSKDA 
      1560       1570       1580       1590       1600
SKLLLLYDDH ILDNDPMRES KDMAYAQAYL NRVREALQDV PGKVEEFLGL 
      1610       1620       1630       1640       1650
LYEFDQAGES HSVIELFAQL KQLLKDWPEL LKDFAAFLLP EQALECGLFE 
      1660       1670       1680       1690       1700
EQQAFERSRR FLRQLEISFG ENPSHYQKIV RALQSGSPLS PAGIEELKTQ 
      1710       1720       1730       1740       1750
MATLLKGHTH LQGEFWMFFD EMRPPPARPG QFEEAVWPED VATGTDGEAG 
      1760       1770       1780       1790       1800
VSVTSRGGVW GGFEEVTLPD LDEDEESHKI RQISSRSKRR KELHTYKDCD 
      1810       1820       1830       1840       1850
WPEKDCSCSC HDSVHDAKHR RHKRKGCLRC QSNKAANGSK VLKGRDSAFS 
      1860       1870       1880       1890       1900
SADAQSERGG EEKEEERVLG EDGEAEKELK DETGSGANSP HHDGEGSVWE 
      1910       1920       1930       1940       1950
REERATSSIP EEQNTHNQDD EEKTEEKNHH ASPEKHSRDE EDSAESGQTE 
      1960       1970       1980       1990       2000
AAQQSSLSPA LDAPVCAKNI SLTPTGERVI LWTREADRVI LTTCQQQGAS 
      2010       2020       2030       2040       2050
QSTFQAVSEQ LGNKTASEVS RRFRDLMRLF HTSASQASSE DEAAEQQSAT 

DEEQD
Length:2,055
Mass (Da):228,431
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE690F9EABCCD8789
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CR848841 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		NP_001188464.1, NM_001201535.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSDART00000088023.4; ENSDARP00000082456.3; ENSDARG00000005867.13

Database of genes from NCBI RefSeq genomes

More...GeneIDi		555764

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dre:555764

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848841 Genomic DNA No translation available.
RefSeqiNP_001188464.1, NM_001201535.1

3D structure databases

AlphaFoldDBiF1QI87
SMRiF1QI87
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000109415

Proteomic databases

PaxDbiF1QI87

Genome annotation databases

EnsembliENSDART00000088023.4; ENSDARP00000082456.3; ENSDARG00000005867.13
GeneIDi555764
KEGGidre:555764

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		555764
ZFINiZDB-GENE-070117-2447, gon4lb

Phylogenomic databases

eggNOGiENOG502QT2W, Eukaryota
GeneTreeiENSGT00940000164105
HOGENOMiCLU_000833_0_0_1
InParanoidiF1QI87
OMAiHRNYKDC
OrthoDBi49443at2759
TreeFamiTF343327

Gene expression databases

BgeeiENSDARG00000005867, Expressed in blastula and 32 other tissues

Family and domain databases

Gene3Di1.20.1160.11, 1 hit
InterProiView protein in InterPro
IPR009057, Homeobox-like_sf
IPR003822, PAH
IPR036600, PAH_sf
PfamiView protein in Pfam
PF02671, PAH, 1 hit
SUPFAMiSSF46689, SSF46689, 1 hit
SSF47762, SSF47762, 2 hits
PROSITEiView protein in PROSITE
PS51477, PAH, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1QI87_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1QI87
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 25, 2022
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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