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UniProtKB - F1QGH7 (CTNB1_DANRE)

Entry version 72 (23 Feb 2022)
Sequence version 1 (03 May 2011)
Previous versions | rss
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Protein

Catenin beta-1

Gene

ctnnb1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Key downstream component of the canonical Wnt signaling pathway (By similarity).

In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity).

In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity).

Plays a key role in dorsoventral patterning: in prospective ventral blastomeres, its down-regulation by axin1 and axin2 leads to inhibit the Wnt signaling pathway, while in prospective dorsal blastomeres, degradation of axin results in stabilization and nuclear translocation of ctnnb1 (PubMed:8562427, PubMed:30467143).

By similarity2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation, Wnt signaling pathway

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DRE-195253, Degradation of beta-catenin by the destruction complex
R-DRE-196299, Beta-catenin phosphorylation cascade
R-DRE-201681, TCF dependent signaling in response to WNT
R-DRE-201722, Formation of the beta-catenin:TCF transactivating complex
R-DRE-3134973, LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
R-DRE-351906, Apoptotic cleavage of cell adhesion proteins
R-DRE-3769402, Deactivation of the beta-catenin transactivating complex
R-DRE-4086398, Ca2+ pathway
R-DRE-418990, Adherens junctions interactions
R-DRE-5218920, VEGFR2 mediated vascular permeability
R-DRE-525793, Myogenesis
R-DRE-5626467, RHO GTPases activate IQGAPs
R-DRE-8853884, Transcriptional Regulation by VENTX
R-DRE-8951430, RUNX3 regulates WNT signaling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Catenin beta-1
Alternative name(s):
Beta-catenin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ctnnb1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Zebrafish Information Network genome database

More...ZFINi		ZDB-GENE-980526-362, ctnnb1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004463741 – 780Catenin beta-1Add BLAST780

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation by gsk3b promotes ubiquitination and subsequent degradation by the proteasome.By similarity
Ubiquitinated when phosphorylated by gsk3b, leading to its degradation.By similarity

Keywords - PTMi

Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F1QGH7

PRoteomics IDEntifications database

More...PRIDEi		F1QGH7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed maternally and is widely distributed in the early embryo (PubMed:8562427). Expressed in the posterior ventral and lateral mesodermal, and ectodermal cells during gastrulation (PubMed:25371059).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSDARG00000014571, Expressed in gastrula and 44 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		7955.ENSDARP00000032935

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1780
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		F1QGH7

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q90424

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati140 – 179ARM 1Sequence analysisAdd BLAST40
Repeati224 – 263ARM 2Sequence analysisAdd BLAST40
Repeati266 – 305ARM 3Sequence analysisAdd BLAST40
Repeati350 – 389ARM 4Sequence analysisAdd BLAST40
Repeati399 – 430ARM 5PROSITE-ProRule annotationAdd BLAST32
Repeati431 – 472ARM 6Sequence analysisAdd BLAST42
Repeati478 – 518ARM 7Sequence analysisAdd BLAST41
Repeati520 – 561ARM 8Sequence analysisAdd BLAST42
Repeati583 – 622ARM 9Sequence analysisAdd BLAST40
Repeati624 – 663ARM 10Sequence analysisAdd BLAST40

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni34 – 56DisorderedSequence analysisAdd BLAST23
Regioni735 – 770DisorderedSequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi34 – 48Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the beta-catenin family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4203, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155471

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_008757_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F1QGH7

Database of Orthologous Groups

More...OrthoDBi		321213at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		F1QGH7

TreeFam database of animal gene trees

More...TreeFami		TF317997

Family and domain databases

Database of protein disorder

More...DisProti		DP02584

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 1 hit

Intrinsically Disordered proteins with Extensive Annotations and Literature

More...IDEALi		IID50014

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR000225, Armadillo
IPR013284, Beta-catenin

The PANTHER Classification System

More...PANTHERi		PTHR45976, PTHR45976, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00514, Arm, 4 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01869, BCATNINFAMLY

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00185, ARM, 12 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50176, ARM_REPEAT, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F1QGH7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATQSDLMEL EMAMDPDRKA AVSHWQQQSY LDSGIHSGAT TTAPSLSGKG 
        60         70         80         90        100
NPEDDDVDNQ VLYEWEQGFN QSFNQEQVAD IDGQYAMTRA QRVRAAMFPE 
       110        120        130        140        150
TLDEGMQIPS TQFDSAHPTN VQRLAEPSQM LKHAVVNLIN YQDDAELATR 
       160        170        180        190        200
AIPELTKLLN DEDQVVVNKA AVMVHQLSKK EASRHAIMRS PQMVSAIVRT 
       210        220        230        240        250
MQNTNDVETA RCTSGTLHNL SHHREGLLAI FKSGGIPALV KMLGSPVDSV 
       260        270        280        290        300
LFYAITTLHN LLLHQEGAKM AVRLAGGLQK MVALLNKTNV KFLAITTDCL 
       310        320        330        340        350
QILAYGNQES KLIILASGGP QALVNIMRTY TYEKLLWTTS RVLKVLSVCS 
       360        370        380        390        400
SNKPAIVEAG GMQALGLHLT DPSQRLVQNC LWTLRNLSDA ATKQEGMEGL 
       410        420        430        440        450
LGTLVQLLGS DDINVVTCAA GILSNLTCNN YKNKMMVCQV GGIEALVRTV 
       460        470        480        490        500
LRAGDREDIT EPAICALRHL TSRHQDAEMA QNAVRLHYGL PVVVKLLHPP 
       510        520        530        540        550
SHWPLIKATV GLIRNLALCP ANHAPLREQG AIPRLVQLLV RAHQDTQRRT 
       560        570        580        590        600
SMGGTQQQFV EGVRMEEIVE GCTGALHILA RDIHNRIVIR GLNTIPLFVQ 
       610        620        630        640        650
LLYSPIENIQ RVAAGVLCEL AQDKEAAEAI EAEGATAPLT ELLHSRNEGV 
       660        670        680        690        700
ATYAAAVLFR MSEDKPQDYK KRLSVELTSS LFRTEPMTWN ETGDLGLDIG 
       710        720        730        740        750
AQGEPLGYRQ DDPSYRSFHS GGYGQDAMGM DPMMEHEMAG HHPGPDYPVD 
       760        770        780
GLPDLGHTQD LIDGLPPGDS NQLAWFDTDL
Length:780
Mass (Da):85,569
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4CBCC6EEBF717F2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5H1ZRJ2A0A5H1ZRJ2_DANRE
Catenin beta-1
ctnnb1
789Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CABZ01038334 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti241K → N in AAC59732 (PubMed:8562427).Curated1
Sequence conflicti242M → V in AAH47815 (Ref. 3) Curated1
Sequence conflicti253Y → H in AAC59732 (PubMed:8562427).Curated1
Sequence conflicti446L → P in AAH47815 (Ref. 3) Curated1
Sequence conflicti571G → A in AAC59732 (PubMed:8562427).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U41081 mRNA Translation: AAC59732.1
CABZ01038334 Genomic DNA No translation available.
BC047815 mRNA Translation: AAH47815.1

NCBI Reference Sequences

More...RefSeqi		NP_571134.2, NM_131059.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSDART00000038495; ENSDARP00000032935; ENSDARG00000014571

Database of genes from NCBI RefSeq genomes

More...GeneIDi		30265

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dre:30265

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41081 mRNA Translation: AAC59732.1
CABZ01038334 Genomic DNA No translation available.
BC047815 mRNA Translation: AAH47815.1
RefSeqiNP_571134.2, NM_131059.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Z6GX-ray3.40A1-780[»]
SMRiF1QGH7
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000032935

Proteomic databases

PaxDbiF1QGH7
PRIDEiF1QGH7

Genome annotation databases

EnsembliENSDART00000038495; ENSDARP00000032935; ENSDARG00000014571
GeneIDi30265
KEGGidre:30265

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		1499
ZFINiZDB-GENE-980526-362, ctnnb1

Phylogenomic databases

eggNOGiKOG4203, Eukaryota
GeneTreeiENSGT00940000155471
HOGENOMiCLU_008757_1_1_1
InParanoidiF1QGH7
OrthoDBi321213at2759
PhylomeDBiF1QGH7
TreeFamiTF317997

Enzyme and pathway databases

ReactomeiR-DRE-195253, Degradation of beta-catenin by the destruction complex
R-DRE-196299, Beta-catenin phosphorylation cascade
R-DRE-201681, TCF dependent signaling in response to WNT
R-DRE-201722, Formation of the beta-catenin:TCF transactivating complex
R-DRE-3134973, LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production
R-DRE-351906, Apoptotic cleavage of cell adhesion proteins
R-DRE-3769402, Deactivation of the beta-catenin transactivating complex
R-DRE-4086398, Ca2+ pathway
R-DRE-418990, Adherens junctions interactions
R-DRE-5218920, VEGFR2 mediated vascular permeability
R-DRE-525793, Myogenesis
R-DRE-5626467, RHO GTPases activate IQGAPs
R-DRE-8853884, Transcriptional Regulation by VENTX
R-DRE-8951430, RUNX3 regulates WNT signaling

Miscellaneous databases

EvolutionaryTraceiQ90424

Protein Ontology

More...PROi		PR:F1QGH7

Gene expression databases

BgeeiENSDARG00000014571, Expressed in gastrula and 44 other tissues

Family and domain databases

DisProtiDP02584
Gene3Di1.25.10.10, 1 hit
IDEALiIID50014
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR000225, Armadillo
IPR013284, Beta-catenin
PANTHERiPTHR45976, PTHR45976, 1 hit
PfamiView protein in Pfam
PF00514, Arm, 4 hits
PRINTSiPR01869, BCATNINFAMLY
SMARTiView protein in SMART
SM00185, ARM, 12 hits
SUPFAMiSSF48371, SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS50176, ARM_REPEAT, 9 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTNB1_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1QGH7
Secondary accession number(s): A0A0N4SUA5, Q7ZU14, Q90424
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 13, 2019
Last sequence update: May 3, 2011
Last modified: February 23, 2022
This is version 72 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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