UniProtKB - F1QE54 (F1QE54_DANRE)
Protein
Submitted name:
Activated leukocyte cell adhesion molecule b
Gene
alcamb
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- identical protein binding Source: ZFIN
GO - Biological processi
- axonogenesis involved in innervation Source: ZFIN
- forebrain cell migration Source: ZFIN
- retinal ganglion cell axon guidance Source: ZFIN
Enzyme and pathway databases
Reactomei | R-DRE-445989, TAK1 activates NFkB by phosphorylation and activation of IKKs complex R-DRE-879415, Advanced glycosylation endproduct receptor signaling R-DRE-933542, TRAF6 mediated NF-kB activation |
Names & Taxonomyi
Protein namesi | Submitted name: Activated leukocyte cell adhesion molecule bImported |
Gene namesi | Name:alcambImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-030131-1768, alcamb |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Single-pass type I membrane protein ARBA annotation
Other locations
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- axon Source: ZFIN
- dendrite Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 504 – 527 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
Cell projectionARBA annotation, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_5003268200 | 22 – 562 | Sequence analysisAdd BLAST | 541 |
Proteomic databases
PaxDbi | F1QE54 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000058538, Expressed in gastrula and 73 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: ZFIN
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000091978 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 128 – 229 | Ig-likeInterPro annotationAdd BLAST | 102 | |
Domaini | 233 – 315 | Ig-likeInterPro annotationAdd BLAST | 83 | |
Domaini | 400 – 482 | Ig-likeInterPro annotationAdd BLAST | 83 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 538 – 562 | DisorderedSequence analysisAdd BLAST | 25 |
Keywords - Domaini
SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502RMQM, Eukaryota |
GeneTreei | ENSGT00940000156881 |
HOGENOMi | CLU_028888_2_0_1 |
InParanoidi | F1QE54 |
OMAi | YPEGNIT |
OrthoDBi | 536204at2759 |
TreeFami | TF321859 |
Family and domain databases
Gene3Di | 2.60.40.10, 4 hits |
InterProi | View protein in InterPro IPR039810, CD166_antigen IPR013162, CD80_C2-set IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set |
PANTHERi | PTHR11973:SF2, PTHR11973:SF2, 1 hit |
Pfami | View protein in Pfam PF08205, C2-set_2, 1 hit PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 3 hits SM00408, IGc2, 3 hits |
SUPFAMi | SSF48726, SSF48726, 4 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 3 hits PS00290, IG_MHC, 1 hit |
i Sequence
Sequence statusi: Complete.
F1QE54-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQRTAFLTCL LTVSLMNQVC GLETVTGKYG DTVEIPCNSG LVSDVGVTFV
60 70 80 90 100
KWKSDKDGSI LVKHTGQNAS SPTDGNYKNR VSIKKDFGLI ITQVSLADQK
110 120 130 140 150
TFTCMVVAAD DILEYPVQLV IYKTPLQPQI ANLTTAMEIG KLTTLAQCHT
160 170 180 190 200
EGANPAANIT WFKNKTPLIA DGTAIKITND VAVDKATGLS ATTSKLEYTA
210 220 230 240 250
VKDDINSKFT CQVQHIKSAN MDSSPLVFTV NYPSETISFH VLPDGPVKEG
260 270 280 290 300
DNVTLKCTAD GNPPPSRYNF YIKGEKKTVE KSNIFILSNV TRQNTGEYKC
310 320 330 340 350
SLVDNEILTA SKNITVEYLD VILSTTGEVF KKLGDSFETT LDIKASGKTE
360 370 380 390 400
TFCKKGGEKM VGPPKFASLK YTDSGVYECV VTMLGLKKTQ TFDLNVHGQP
410 420 430 440 450
LIKSLTKKRG DGTNKILSCE AEGSPKPTVQ WITNGTDVKF QESEHVNGKI
460 470 480 490 500
TYYITVSPKA NVTVSCTISN DLGSDTRSID VSSLVEDVTM DKQDQSEDYS
510 520 530 540 550
DQTALAVGIV VGLMLAALLI GLAYWLYMKK FRQGSWKTGE KEDGSAEESK
560
KLEENQSQKA EV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR848759 Genomic DNA No translation available. |
RefSeqi | NP_997799.3, NM_212634.3 |
Genome annotation databases
Ensembli | ENSDART00000101204; ENSDARP00000091978; ENSDARG00000058538 |
GeneIDi | 323919 |
KEGGi | dre:323919 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR848759 Genomic DNA No translation available. |
RefSeqi | NP_997799.3, NM_212634.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000091978 |
Proteomic databases
PaxDbi | F1QE54 |
Genome annotation databases
Ensembli | ENSDART00000101204; ENSDARP00000091978; ENSDARG00000058538 |
GeneIDi | 323919 |
KEGGi | dre:323919 |
Organism-specific databases
CTDi | 323919 |
ZFINi | ZDB-GENE-030131-1768, alcamb |
Phylogenomic databases
eggNOGi | ENOG502RMQM, Eukaryota |
GeneTreei | ENSGT00940000156881 |
HOGENOMi | CLU_028888_2_0_1 |
InParanoidi | F1QE54 |
OMAi | YPEGNIT |
OrthoDBi | 536204at2759 |
TreeFami | TF321859 |
Enzyme and pathway databases
Reactomei | R-DRE-445989, TAK1 activates NFkB by phosphorylation and activation of IKKs complex R-DRE-879415, Advanced glycosylation endproduct receptor signaling R-DRE-933542, TRAF6 mediated NF-kB activation |
Gene expression databases
Bgeei | ENSDARG00000058538, Expressed in gastrula and 73 other tissues |
Family and domain databases
Gene3Di | 2.60.40.10, 4 hits |
InterProi | View protein in InterPro IPR039810, CD166_antigen IPR013162, CD80_C2-set IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003599, Ig_sub IPR003598, Ig_sub2 IPR013106, Ig_V-set |
PANTHERi | PTHR11973:SF2, PTHR11973:SF2, 1 hit |
Pfami | View protein in Pfam PF08205, C2-set_2, 1 hit PF07686, V-set, 1 hit |
SMARTi | View protein in SMART SM00409, IG, 3 hits SM00408, IGc2, 3 hits |
SUPFAMi | SSF48726, SSF48726, 4 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 3 hits PS00290, IG_MHC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1QE54_DANRE | |
Accessioni | F1QE54Primary (citable) accession number: F1QE54 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 3, 2011 | |
Last modified: | February 10, 2021 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |