UniProtKB - F1QAZ9 (F1QAZ9_DANRE)
Protein
Heterogeneous nuclear ribonucleoprotein K
Gene
hnrnpk
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- mRNA binding Source: GO_Central
GO - Biological processi
- regulation of gene expression Source: GO_Central
- regulation of mRNA splicing, via spliceosome Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | ActivatorARBA annotation, DNA-bindingARBA annotation, RepressorARBA annotation |
Biological process | mRNA processing, mRNA splicing |
Names & Taxonomyi
Protein namesi | Recommended name: Heterogeneous nuclear ribonucleoprotein KARBA annotation |
Gene namesi | Name:hnrnpkImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-040426-1926, hnrnpk |
Subcellular locationi
Nucleus
- nucleoplasm ARBA annotation
Nucleus
- nucleoplasm Source: UniProtKB-SubCell
- nucleus Source: GO_Central
- spliceosomal complex Source: UniProtKB-KW
Other locations
- cytoplasm Source: GO_Central
Keywords - Cellular componenti
NucleusARBA annotation, SpliceosomeARBA annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000018914, Expressed in mature ovarian follicle and 38 other tissues |
ExpressionAtlasi | F1QAZ9, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 41 – 106 | KHInterPro annotationAdd BLAST | 66 | |
Domaini | 119 – 190 | KHInterPro annotationAdd BLAST | 72 | |
Domaini | 340 – 410 | KHInterPro annotationAdd BLAST | 71 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 38 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 222 – 338 | DisorderedSequence analysisAdd BLAST | 117 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 9 – 38 | PolyampholyteSequence analysisAdd BLAST | 30 | |
Compositional biasi | 289 – 322 | PolyampholyteSequence analysisAdd BLAST | 34 |
Phylogenomic databases
GeneTreei | ENSGT00940000153434 |
HOGENOMi | CLU_022670_5_1_1 |
OMAi | KCVEMII |
Family and domain databases
Gene3Di | 3.30.1370.10, 3 hits |
InterProi | View protein in InterPro IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR012987, ROK_N |
Pfami | View protein in Pfam PF00013, KH_1, 3 hits PF08067, ROKNT, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 3 hits |
SUPFAMi | SSF54791, SSF54791, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F1QAZ9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDPENDPQEE ETFSNKESNG KRSADDSEEE KPYKRSRNSD EMVELRILLQ
60 70 80 90 100
SKNAGAVIGK GGKNIKALRT DYNATVSVPD SSGPERILSV SADIPTVAEI
110 120 130 140 150
LLKIIPTLEE YQHHKGVDFD CELRLLIHQS LAGSIIGLKG AKIKELRDST
160 170 180 190 200
QTTIKLFQEC CPQSTDRVVL VGGKAERVVQ CIKTMLELIV EAPIKGRAQQ
210 220 230 240 250
YDPNFYDETY DYGGFGVMYE ERGRRPMGGF SSRGRSSSGG FDRMPSGGRG
260 270 280 290 300
GGHHMQSRRD YDDISPRRGP PPSQRGGGRG PRPPRNMGPP HHRRSDDQYY
310 320 330 340 350
SSQRGHMDER RHGERRGRND RYGGSMNDGY GGRSSYSDGP VITTQVTIPK
360 370 380 390 400
DLAGSIIGKG GQRIKQIRHE SGASIKIDEP LQGSEDRIIT ITGTQDQIQN
410 420
AQYLLQNRYD LALHLLGRQN
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF1QWB4 | F1QWB4_DANRE | Heterogeneous nuclear ribonucleopro... | hnrnpk | 429 | Annotation score: | ||
E9QGT0 | E9QGT0_DANRE | Heterogeneous nuclear ribonucleopro... | hnrnpk | 148 | Annotation score: | ||
A0A2R8Q139 | A0A2R8Q139_DANRE | Heterogeneous nuclear ribonucleopro... | hnrnpk | 417 | Annotation score: | ||
B0UXJ3 | B0UXJ3_DANRE | Heterogeneous nuclear ribonucleopro... | hnrnpk | 281 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR376792 Genomic DNA No translation available. CU682767 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000147309; ENSDARP00000120947; ENSDARG00000018914 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR376792 Genomic DNA No translation available. CU682767 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000147309; ENSDARP00000120947; ENSDARG00000018914 |
Organism-specific databases
ZFINi | ZDB-GENE-040426-1926, hnrnpk |
Phylogenomic databases
GeneTreei | ENSGT00940000153434 |
HOGENOMi | CLU_022670_5_1_1 |
OMAi | KCVEMII |
Gene expression databases
Bgeei | ENSDARG00000018914, Expressed in mature ovarian follicle and 38 other tissues |
ExpressionAtlasi | F1QAZ9, baseline |
Family and domain databases
Gene3Di | 3.30.1370.10, 3 hits |
InterProi | View protein in InterPro IPR004087, KH_dom IPR004088, KH_dom_type_1 IPR036612, KH_dom_type_1_sf IPR012987, ROK_N |
Pfami | View protein in Pfam PF00013, KH_1, 3 hits PF08067, ROKNT, 1 hit |
SMARTi | View protein in SMART SM00322, KH, 3 hits |
SUPFAMi | SSF54791, SSF54791, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1QAZ9_DANRE | |
Accessioni | F1QAZ9Primary (citable) accession number: F1QAZ9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 3, 2011 | |
Last modified: | April 7, 2021 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |