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Protein

O-acyltransferase

Gene

dgat1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei431UniRule annotation1

GO - Molecular functioni

GO - Biological processi

  • response to yeast Source: ZFIN
  • triglyceride biosynthetic process Source: GO_Central

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

ReactomeiR-DRE-1482883 Acyl chain remodeling of DAG and TAG
R-DRE-6798695 Neutrophil degranulation
R-DRE-75109 Triglyceride biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
O-acyltransferaseUniRule annotation
Gene namesi
Name:dgat1bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-040718-158 dgat1b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei96 – 117HelicalSequence analysisAdd BLAST22
Transmembranei137 – 159HelicalSequence analysisAdd BLAST23
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Transmembranei340 – 358HelicalSequence analysisAdd BLAST19
Transmembranei442 – 460HelicalSequence analysisAdd BLAST19
Transmembranei472 – 490HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1Q9Z3

Expressioni

Gene expression databases

BgeeiENSDARG00000054914
ExpressionAtlasiF1Q9Z3 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000071653

Family & Domainsi

Sequence similaritiesi

Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0380 Eukaryota
COG5056 LUCA
GeneTreeiENSGT00530000063122
InParanoidiF1Q9Z3
OMAiHLLWLMF
OrthoDBiEOG091G0GW2
TreeFamiTF314921

Family and domain databases

InterProiView protein in InterPro
IPR027251 Diacylglycerol_acylTrfase1
IPR004299 MBOAT_fam
IPR014371 Oat_ACAT_DAG_ARE
PANTHERiPTHR10408 PTHR10408, 1 hit
PfamiView protein in Pfam
PF03062 MBOAT, 1 hit
PIRSFiPIRSF000439 Oat_ACAT_DAG_ARE, 1 hit
PIRSF500231 Oat_dag, 1 hit

Sequencei

Sequence statusi: Complete.

F1Q9Z3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDKDDFGPV TRNRRRATIT STRSESVKLR NGASAAAAAA DSGLKSGHKA
60 70 80 90 100
RESLAKNLQL NEENKRKCDR YDRMSCHKLQ ESMLSSASSF KNYRGILNWC
110 120 130 140 150
VVMLVLSNAR LFLENLLRYG ILVDPIQVVS LFLKDPYSWP AACLVIVCNA
160 170 180 190 200
FILVALYTER KLAMGSISEK VGLLIYIFNL TIILCFPMVV VLKLPSITPV
210 220 230 240 250
GGAFALGIYT ILFLKLYSYK DVNKWCRERT QAKARSLSRS LSCPSPPSTS
260 270 280 290 300
SSMQSYVSYP GNLSLRDIYY FVFAPTLCYE LNFPRSESIR MGFLLRRLFE
310 320 330 340 350
MLLLTQLLVG LTQQWMVPII RSSMKPLQEM DYTRMTERLL RLAVPNHLLW
360 370 380 390 400
LIFFYSFFHS SMNFMAELLR FGDREFYRDW WNSETITYFW QNWNIPVHKW
410 420 430 440 450
CLRHFYKPLL RRGAGKLLSQ SAVFFASAFF HEYLVSVPLR MFRLWAFMGM
460 470 480 490 500
MAQIPLAWLV SRFLRGNYGN AAVWLSLIIG QPIAVLMYVH DYYVTNHQDD

LTINEDL
Length:507
Mass (Da):58,702
Last modified:May 3, 2011 - v1
Checksum:iC639DC419CC84BB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX510336 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000077185; ENSDARP00000071653; ENSDARG00000054914

Similar proteinsi

Entry informationi

Entry nameiF1Q9Z3_DANRE
AccessioniPrimary (citable) accession number: F1Q9Z3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: March 28, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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