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Protein

Protein Wnt

Gene

wnt7ba

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-3238698 WNT ligand biogenesis and trafficking

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:wnt7baImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 4

Organism-specific databases

ZFINiZDB-GENE-041210-178 wnt7ba

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 42HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Membrane, Secreted

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiF1Q5B7

Expressioni

Gene expression databases

BgeeiENSDARG00000022858 Expressed in 18 organ(s), highest expression level in swim bladder
ExpressionAtlasiF1Q5B7 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000011793

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
GeneTreeiENSGT00760000118943
InParanoidiF1Q5B7
KOiK00572
OrthoDBiEOG091G0OFF
TreeFamiTF105310

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR013300 Wnt7
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01891 WNT7PROTEIN
PR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F1Q5B7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSISSCGAL LSVYYPQIFL ILTSGSYLAL SSVVALGANI ICNKIPGLAP
60 70 80 90 100
RQRAICQSRP DAIIIIGEGA QLGINECQYQ FRYGRWNCSA LGERTVFGQE
110 120 130 140 150
LRVGSKEAAF TYAITAAGVA HAVTAACSQG NLSHCGCDRE KQGYHDQEEG
160 170 180 190 200
WKWGGCSADV KYGVEFSRRF VDAREIKKNA RRLMNLHNNE AGRKVLEERM
210 220 230 240 250
KLECKCHGVS GSCTTKTCWT TLPKFREIGY VLKERYTTAL EVEAVRATRF
260 270 280 290 300
RQPSFLRLKQ SRGYIKPTDT DLVFLERSPN YCEEDTVTGS AGTRGRLCNH
310 320 330 340 350
TSPLTDGCNL MCCGRGHNTH QYTRVWQCNC KFQWCCFVKC NTCSEKTEVF

TCK
Length:353
Mass (Da):39,517
Last modified:May 3, 2011 - v1
Checksum:i85E93B9CA47A482F
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1RCY4F1RCY4_DANRE
Protein Wnt
wnt7ba
338Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX649425 Genomic DNA No translation available.
RefSeqiXP_691878.2, XM_686786.5

Genome annotation databases

EnsembliENSDART00000003156; ENSDARP00000011793; ENSDARG00000022858
GeneIDi563427
KEGGidre:563427

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX649425 Genomic DNA No translation available.
RefSeqiXP_691878.2, XM_686786.5

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000011793

Proteomic databases

PaxDbiF1Q5B7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000003156; ENSDARP00000011793; ENSDARG00000022858
GeneIDi563427
KEGGidre:563427

Organism-specific databases

CTDi563427
ZFINiZDB-GENE-041210-178 wnt7ba

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
GeneTreeiENSGT00760000118943
InParanoidiF1Q5B7
KOiK00572
OrthoDBiEOG091G0OFF
TreeFamiTF105310

Enzyme and pathway databases

ReactomeiR-DRE-3238698 WNT ligand biogenesis and trafficking

Gene expression databases

BgeeiENSDARG00000022858 Expressed in 18 organ(s), highest expression level in swim bladder
ExpressionAtlasiF1Q5B7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR013300 Wnt7
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01891 WNT7PROTEIN
PR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1Q5B7_DANRE
AccessioniPrimary (citable) accession number: F1Q5B7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 12, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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