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Entry version 60 (13 Nov 2019)
Sequence version 1 (03 May 2011)
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Protein
Submitted name:

Complement component 4

Gene

c4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DRE-166663 Initial triggering of complement
R-DRE-174577 Activation of C3 and C5
R-DRE-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-DRE-8957275 Post-translational protein phosphorylation
R-DRE-977606 Regulation of Complement cascade

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Complement component 4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:c4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-030131-5697 c4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

SecretedSAAS annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500326951418 – 1700Sequence analysisAdd BLAST1683

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1Q4X5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000015065 Expressed in 23 organ(s), highest expression level in head

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F1Q4X5 differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000031658

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini685 – 720Anaphylatoxin-likeInterPro annotationAdd BLAST36
Domaini1547 – 1698NTRInterPro annotationAdd BLAST152

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IMYI Eukaryota
COG2373 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155739

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1Q4X5

KEGG Orthology (KO)

More...
KOi
K03989

Identification of Orthologs from Complete Genome Data

More...
OMAi
VKDVCKG

Database of Orthologous Groups

More...
OrthoDBi
28894at2759

TreeFam database of animal gene trees

More...
TreeFami
TF313285

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00017 ANATO, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.50.120, 1 hit
2.60.40.10, 2 hits
2.60.40.690, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009048 A-macroglobulin_rcpt-bd
IPR036595 A-macroglobulin_rcpt-bd_sf
IPR011625 A2M_N_BRD
IPR011626 Alpha-macroglobulin_TED
IPR000020 Anaphylatoxin/fibulin
IPR018081 Anaphylatoxin_comp_syst
IPR041425 C3/4/5_MG1
IPR037569 Complement_C4A
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR001599 Macroglobln_a2
IPR019742 MacrogloblnA2_CS
IPR002890 MG2
IPR041555 MG3
IPR001134 Netrin_domain
IPR018933 Netrin_module_non-TIMP
IPR008930 Terpenoid_cyclase/PrenylTrfase
IPR008993 TIMP-like_OB-fold

The PANTHER Classification System

More...
PANTHERi
PTHR11412:SF86 PTHR11412:SF86, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00207 A2M, 1 hit
PF07703 A2M_BRD, 1 hit
PF07677 A2M_recep, 1 hit
PF01821 ANATO, 1 hit
PF17790 MG1, 1 hit
PF01835 MG2, 1 hit
PF17791 MG3, 1 hit
PF01759 NTR, 1 hit
PF07678 TED_complement, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01360 A2M, 1 hit
SM01359 A2M_N_2, 1 hit
SM01361 A2M_recep, 1 hit
SM00104 ANATO, 1 hit
SM00643 C345C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47686 SSF47686, 1 hit
SSF48239 SSF48239, 1 hit
SSF49410 SSF49410, 1 hit
SSF50242 SSF50242, 1 hit
SSF81296 SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00477 ALPHA_2_MACROGLOBULIN, 1 hit
PS01178 ANAPHYLATOXIN_2, 1 hit
PS50189 NTR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F1Q4X5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIYHLFFVVF GIYVVDAQKP TCLIVAPNVI HLGVEETVGV QLHGATKEIR
60 70 80 90 100
MKLYFEKQKE SEILSEIRSI ILNENNNYQA VVKLKVDATM YGDVEKNSYV
110 120 130 140 150
QLAAISNDIF EKQDARKANI YLSTKRGYIF VQTDKPIYNP GENVKYRIFI
160 170 180 190 200
LDNYMLPIQD ELHVQITNSK GLIVYNRVLI INQILDKTIT IPEVEQTGKW
210 220 230 240 250
KIITSFHKFP ESTTTVEFEV KEYVLPTFEV KIEASQPYHI LMSESFPFNI
260 270 280 290 300
SARYTYGKGV NGIAYVRFGL VDEKHNKIYL PGTEKQITVE DGTAGTAVLT
310 320 330 340 350
KDLKTASQNI TQGYIEGYYI YIAVSVLDKA SGMLEEAESS SVKIVTSPYV
360 370 380 390 400
VDLSKTKTYF TPGGVFSVLA TATYPDGNRA PNLKFTATIT IDGSSEQILQ
410 420 430 440 450
NESWGNEMGD VAMSFQIPPQ AKNLAITVFA EGGDQVVIRS DNKMTASAIT
460 470 480 490 500
AEEQSYLSLE VEKQFLQAGE DLKARLRDIT PEGAAKPTFF YFMVWSKGQI
510 520 530 540 550
VQMGRVPRTA FTTVNVKVNV DMVPSFRLVA YYFTGSASKE SVVADSVWVD
560 570 580 590 600
VKDVCKGKIE INPLAEIKPA TQFEVTVETN PKTKVALVAV DSAVYILNKN
610 620 630 640 650
KLSLQKMFDY MNSYDLACSV GGGEDSSAVL QRAGLTFICN CALKTPTALE
660 670 680 690 700
HKCNKKTTNR VRRAPDYVAK YNAVVNSFKN QDRKCCLDGV RPSKMQTSCV
710 720 730 740 750
DRLKRVKESE SCRKAFKECC EAADERRKRE KFEKRKTSLG RVVGDSFDEI
760 770 780 790 800
VINEDLIYIR NYFPQSWMWT VIESDNKGLI RHEVVAPDSI TTWEVQAVGI
810 820 830 840 850
SPTKGFCIAE PKPLTVFKDF FLSVNLPYSV KRNEQLQVKA VVYNYKQESL
860 870 880 890 900
KVIVKLNKVE GLCTAGGNDV KEEVTVSGNS AVTVYFTVVP LIIGNLHIDV
910 920 930 940 950
LAYASEIIHD RVEKKLRVEG EGELTSIDRE FNIDPNLKKI EFNISSPVDE
960 970 980 990 1000
VPAGSDSETS LGFKGGVMGE SIDNCLNLEG IDKLIQLPTG CAEQTMVKMS
1010 1020 1030 1040 1050
PAIHAMRYLD ATNQWLSLKA ERRDEARSMI QTGYNTVLTH KKDDGSYGAF
1060 1070 1080 1090 1100
LRTPSSIWLT AFIAKELTGS QDIVNVNKLY IQEAMSYLIS KQKSNGAWDD
1110 1120 1130 1140 1150
PNRLFDQGMK GGVEQATDDV PLTAFVLISM HHALKVYDLG SDTELRVAMD
1160 1170 1180 1190 1200
KAKSYLEAQL DAVRSPYSLA VTAYSFSLHD HRSAEARKAQ QKLQDIANCD
1210 1220 1230 1240 1250
DKMCFWKAKG GRGEPKDKAD ARSVETTAYA LLTTLIVGDK SKSKLIANWL
1260 1270 1280 1290 1300
TEQRRHGGGF RSTQDTVLAL EALTKYSIQN NDVDDLNLRV EMCLENGQKK
1310 1320 1330 1340 1350
DLHLTKNNAL TLSAVKVRDV GKVTLNIQGT GRGTLAVVQT YRTMKKDESF
1360 1370 1380 1390 1400
CDLFHLTVTV KGELEYKTDN SQDLLEDYYE SYDTSEAQND EPMSNMQWFD
1410 1420 1430 1440 1450
LRSRRKRQIS EEPIKESSLI YTVCVGLKKK NSEGMIIVDI SLLSGLIPNS
1460 1470 1480 1490 1500
KDLEHNVKGT EKYIDHYEIH HNKVYLYFAK ITETEECLQF GADQAVPMGL
1510 1520 1530 1540 1550
VQPASAVIYD YYSPEKRCGI FYTAPQKSPM ISKLCQGDVC TCAEGGCAKL
1560 1570 1580 1590 1600
KVTFSKNMES NSRSSFACYD PSVDYVYVIK ILSSRSDDVF MYYTTLITDV
1610 1620 1630 1640 1650
LQTGRTGFDS EIQKGETRQM IQRLSCELEL KDEAQYLLMG HDRAISEQNN
1660 1670 1680 1690 1700
NRQQTKYILN SDMWIEKIPE EKRCKSTTSR SACFLLTEFI KQHPIKGCDI
Length:1,700
Mass (Da):191,048
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0A599FED1231CBF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8RSM2A0A2R8RSM2_DANRE
Complement component 4
c4
1,669Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
X1WBY4X1WBY4_DANRE
Complement component 4
c4
203Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL935181 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_005157429.1, XM_005157372.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000028349; ENSDARP00000031658; ENSDARG00000015065

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
566261

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:566261

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL935181 Genomic DNA No translation available.
RefSeqiXP_005157429.1, XM_005157372.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000031658

Proteomic databases

PaxDbiF1Q4X5

Genome annotation databases

EnsembliENSDART00000028349; ENSDARP00000031658; ENSDARG00000015065
GeneIDi566261
KEGGidre:566261

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
566261
ZFINiZDB-GENE-030131-5697 c4

Phylogenomic databases

eggNOGiENOG410IMYI Eukaryota
COG2373 LUCA
GeneTreeiENSGT00940000155739
InParanoidiF1Q4X5
KOiK03989
OMAiVKDVCKG
OrthoDBi28894at2759
TreeFamiTF313285

Enzyme and pathway databases

ReactomeiR-DRE-166663 Initial triggering of complement
R-DRE-174577 Activation of C3 and C5
R-DRE-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-DRE-8957275 Post-translational protein phosphorylation
R-DRE-977606 Regulation of Complement cascade

Gene expression databases

BgeeiENSDARG00000015065 Expressed in 23 organ(s), highest expression level in head
ExpressionAtlasiF1Q4X5 differential

Family and domain databases

CDDicd00017 ANATO, 1 hit
Gene3Di2.40.50.120, 1 hit
2.60.40.10, 2 hits
2.60.40.690, 1 hit
InterProiView protein in InterPro
IPR009048 A-macroglobulin_rcpt-bd
IPR036595 A-macroglobulin_rcpt-bd_sf
IPR011625 A2M_N_BRD
IPR011626 Alpha-macroglobulin_TED
IPR000020 Anaphylatoxin/fibulin
IPR018081 Anaphylatoxin_comp_syst
IPR041425 C3/4/5_MG1
IPR037569 Complement_C4A
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR001599 Macroglobln_a2
IPR019742 MacrogloblnA2_CS
IPR002890 MG2
IPR041555 MG3
IPR001134 Netrin_domain
IPR018933 Netrin_module_non-TIMP
IPR008930 Terpenoid_cyclase/PrenylTrfase
IPR008993 TIMP-like_OB-fold
PANTHERiPTHR11412:SF86 PTHR11412:SF86, 1 hit
PfamiView protein in Pfam
PF00207 A2M, 1 hit
PF07703 A2M_BRD, 1 hit
PF07677 A2M_recep, 1 hit
PF01821 ANATO, 1 hit
PF17790 MG1, 1 hit
PF01835 MG2, 1 hit
PF17791 MG3, 1 hit
PF01759 NTR, 1 hit
PF07678 TED_complement, 1 hit
SMARTiView protein in SMART
SM01360 A2M, 1 hit
SM01359 A2M_N_2, 1 hit
SM01361 A2M_recep, 1 hit
SM00104 ANATO, 1 hit
SM00643 C345C, 1 hit
SUPFAMiSSF47686 SSF47686, 1 hit
SSF48239 SSF48239, 1 hit
SSF49410 SSF49410, 1 hit
SSF50242 SSF50242, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00477 ALPHA_2_MACROGLOBULIN, 1 hit
PS01178 ANAPHYLATOXIN_2, 1 hit
PS50189 NTR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1Q4X5_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1Q4X5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 13, 2019
This is version 60 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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