Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

NLR family pyrin domain containing 8

Gene

NLRP8

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
NLR family pyrin domain containing 8Imported
Gene namesi
Name:NLRP8Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:43851 NLRP8

PTM / Processingi

Proteomic databases

PaxDbiF1PS97

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000003649

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 135PyrinInterPro annotationAdd BLAST97
Domaini216 – 420NACHTInterPro annotationAdd BLAST205

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IJVQ Eukaryota
ENOG410Y5EC LUCA
GeneTreeiENSGT00900000140813
InParanoidiF1PS97
OMAiFPGRLAW
OrthoDBiEOG091G01CG

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF13516 LRR_6, 3 hits
PF05729 NACHT, 1 hit
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50824 DAPIN, 1 hit
PS50837 NACHT, 1 hit

Sequencei

Sequence statusi: Complete.

F1PS97-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQKSGPSPS GSPSRSSSCS SSCSSCSSSS PCYLISSLMS SASSTSPFEN
60 70 80 90 100
GVMLYMVYLS KEELQTFKQL LVDERPRPGS VQITWDQVKT ARWGEVVHLL
110 120 130 140 150
MEYFPGRLAW DVTHDIFAKM NQMELCLRVQ MELNDILPSL ELEDSNPREM
160 170 180 190 200
PVSLEEGESD KIQEYKLYMI DEYSMIRSKT TWPGNHMDFF YQDIERHERF
210 220 230 240 250
LPCIFLPKRP QGRQPKTVVL QGVSGVGKSS LAGKVMLEWA KNKFYSHKFW
260 270 280 290 300
YAFYFHCREV AQVDEQSLSE LIAHKWPRAQ ALMSKIMSKP DQLLLLFDGF
310 320 330 340 350
EEVTLTLTDR PTDLSEDWSQ KLPGSVLLTS LLSKIMLPEA TLLITLRFTS
360 370 380 390 400
WRKLKPFLKH PSFITLTGFS MVEKVKYFRT YFRNKREADE ALSFVMGNTI
410 420 430 440 450
LFSMCQVPVI CWMVCSCLRQ QMEKGVDLVQ AYPNATAVFV QYLSSLFPTK
460 470 480 490 500
AGSLPSNTHQ EQLRGLCYLA AEGMWNMRWV FDMKDFEQAK LDETAVATFL
510 520 530 540 550
HVNIFRRVAG DKDYYAFADL SFQEFFAALL YVLCFPQRLR NFWVLDRVQI
560 570 580 590 600
ICLIAYPGRK KNHLAQMGLF LFGLLNEKCS LAAEKSFRCK LSLGNKKKLL
610 620 630 640 650
KVAALPYECG PPTLHHGIPQ LFYCLHEIQE EAFVSQILSD CQKAALIISR
660 670 680 690 700
NKDMQASAFC LKHCRHLRNL ELTITLTITQ LYALNPDPLQ STEPGSSNQC
710 720 730 740 750
FLWWQDFCSV VRTHENLEVL AVTNTVMEAD SVKVLSAALR HPGCKLQKLI
760 770 780 790 800
FRRVNTSMLN EDLLQVLMEN WYLRCLEIQG TEVRCEAMEF LCTALKYPQC
810 820 830 840 850
YLQCLRLEDC AVTPKSWVEL ARDLGSNRHL KTLMLRSSCL ETFGAYYLSL
860 870 880 890 900
AQLERLLLEN CGLTVLSCKS LMSSLMSNKM LTHLSLAENA LKDEGAKQLC
910 920 930 940 950
SALQHPMCPL QRLVLRNCAL TSDCCQDMAS ALGKNKNLRS LDLGFNSLKD
960 970 980 990 1000
DGVTLLFEAL KKSESGLQIL ELERCLFTSL CCQAMASMLL HNQSLRYLDV
1010 1020
SKNDIGLRGI LLLREAFQQH KWKKKVVL
Length:1,028
Mass (Da):117,420
Last modified:October 31, 2012 - v2
Checksum:i8DFD339BC3512191
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03000720 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000003948; ENSCAFP00000003649; ENSCAFG00000024197

Similar proteinsi

Entry informationi

Entry nameiF1PS97_CANLF
AccessioniPrimary (citable) accession number: F1PS97
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: June 20, 2018
This is version 46 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health