Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 66 (08 May 2019)
Sequence version 1 (03 May 2011)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Collagen type VII alpha 1 chain

Gene

COL7A1

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CFA-1442490 Collagen degradation
R-CFA-1474244 Extracellular matrix organization
R-CFA-1650814 Collagen biosynthesis and modifying enzymes
R-CFA-2022090 Assembly of collagen fibrils and other multimeric structures
R-CFA-204005 COPII-mediated vesicle transport
R-CFA-216083 Integrin cell surface interactions
R-CFA-2214320 Anchoring fibril formation
R-CFA-3000157 Laminin interactions
R-CFA-5694530 Cargo concentration in the ER
R-CFA-8948216 Collagen chain trimerization

Protein family/group databases

MEROPS protease database

More...
MEROPSi
I02.967

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Collagen type VII alpha 1 chainImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COL7A1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9615 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002254 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:39483 COL7A1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500326757924 – 2936Sequence analysisAdd BLAST2913

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1PIP7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSCAFG00000012403 Expressed in 3 organ(s), highest expression level in prefrontal cortex

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9612.ENSCAFP00000018349

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F1PIP7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini38 – 211VWFAInterPro annotationAdd BLAST174
Domaini234 – 329Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini330 – 416Fibronectin type-IIIInterPro annotationAdd BLAST87
Domaini417 – 507Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini510 – 597Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini600 – 687Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini688 – 775Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini778 – 866Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini869 – 957Fibronectin type-IIIInterPro annotationAdd BLAST89
Domaini958 – 1050Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini1054 – 1229VWFAInterPro annotationAdd BLAST176
Domaini2868 – 2921BPTI/Kunitz inhibitorInterPro annotationAdd BLAST54

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3544 Eukaryota
ENOG410ZJNQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154865

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1PIP7

Identification of Orthologs from Complete Genome Data

More...
OMAi
YRVSWHS

Database of Orthologous Groups

More...
OrthoDBi
67372at2759

TreeFam database of animal gene trees

More...
TreeFami
TF351645

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 9 hits
cd00109 KU, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 9 hits
3.40.50.410, 2 hits
4.10.410.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01391 Collagen, 10 hits
PF00041 fn3, 9 hits
PF00014 Kunitz_BPTI, 1 hit
PF00092 VWA, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00759 BASICPTASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060 FN3, 9 hits
SM00327 VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 6 hits
SSF53300 SSF53300, 2 hits
SSF57362 SSF57362, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit
PS50853 FN3, 9 hits
PS50234 VWFA, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1PIP7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLPLLVAAL CAGILAGALR VRAQQRERVT CTRLYAADIV FLLDGSSSIG
60 70 80 90 100
RGNFREVRGF LEGLVWPFSG AASAQGVRFA AVQYSDDPRT EFGLGALGSG
110 120 130 140 150
GDVIRAIREL SYKGGNTRTG AAILHVADHV FLPQLARPGV PKVCILITDG
160 170 180 190 200
KSQDLVDTAA QRLKGQGVKL FAVGIKNADP EELKRVASQP TSDFFFFVND
210 220 230 240 250
FSILRTLLPL VSRRVCTTAG GVPVTLPADD LTSGPRDLVL SEAGSQSLRV
260 270 280 290 300
QWTAASGPVT GYKVQYTPLT GLGQPLPSER REVSVPAGET STQLQGLRPL
310 320 330 340 350
TEYQVTVVAL YANSIGEAVS GTARTTALEG PELTIQNTTT HSLLVAWRSV
360 370 380 390 400
PGATGYRVTW RVLSGGVTQQ QELGPGQGSV LLRDLEPGTD YEVTVSSLLG
410 420 430 440 450
RSIGSASSLT ARTDTSVEQT LRPVILGPTS ILVSWNLVPE ARGYRLEWRR
460 470 480 490 500
ESGLGVPQKV VLPSDVTRYQ LDGLQPGTEY RLTLYTLLEG REVATPATVV
510 520 530 540 550
PTGPELPVGP VTDLQATELP GQRVRVSWSP VPGATEYRIT VRSAQGVERT
560 570 580 590 600
LVLPGSQTAF DLDDVRAGLS YTVRVSARVG TREGGASILT VRRELEAPLA
610 620 630 640 650
IPGLRVVASD ATRVRVAWGP VPGASGFRIS WRTDGGPESS QTLPPESTAT
660 670 680 690 700
DILGLRPGTS YQVAVSALRG REESPPVVIV AQTDPLGPVR TVHVTQTSSS
710 720 730 740 750
SVTIAWNRVP GATGYRVSWH SGHGPEKSQL VSGEATVAEL DGLEPDTEYR
760 770 780 790 800
VHVRAHVAGV DGTPASVVVR TDPAPVGSVS KLQILNASSD VLRVTWVGVT
810 820 830 840 850
GATAYRLAWG RSEGGPTRQQ MLPGNTDSAE IRGLEGGVSY SVRVTALVGD
860 870 880 890 900
REGAPVSIVV TTPPEAPPAL ETLRVVQRGE HSLRLRWRPV PGARGFRLRW
910 920 930 940 950
RPEGGQEQSR VLGPDLSSYE LDGLEPATLY RMWLSVLGPA GEGPPMEVTA
960 970 980 990 1000
YTESLRVPSS ELRVVDTSVD SVTLAWTPVS GVSSYILSWR PLGRPGQDIP
1010 1020 1030 1040 1050
GASQTLPGIS SSQQVTGLEP GISYTFSLTP IREGVRGPEA SLTQKPVCPR
1060 1070 1080 1090 1100
GLMDVVFLLH TTQDNAHRAE AVKRALERLV SALGPLGPQA VQVGLLSYSH
1110 1120 1130 1140 1150
RPSPLFPLNS SYNPDVILQK IHSIPYVDPS GNNLGTAVVT AHRHLLAPDA
1160 1170 1180 1190 1200
PGRRQHIPGI MVLLVDEPLR GDIFNPIREA QAAGLKVMIL GQAGADPEQL
1210 1220 1230 1240 1250
RRLVPGMDPV QTFFAVDDGS SLDRAVSGLA TSLCQIGSTI QPQPEPCTVH
1260 1270 1280 1290 1300
CPKGQKGEPG EMGLKGQAGP PGPPGLPGRI GVPGPQGPPG GTVAKGERGF
1310 1320 1330 1340 1350
PGADGPPGSP GRPGTPGTPG SKGSPGWPGP RGETGERGPR GPKGEPGEPG
1360 1370 1380 1390 1400
RVIGGGGPGL PGQKGDPGLP GLPGSRGPLG DPGPRGPPGL PGTAVKGDKG
1410 1420 1430 1440 1450
DRGERGPPGP GDGSTAPGEP GLPGLPGSPG PQGPVGPSGE KGEKGDCEDG
1460 1470 1480 1490 1500
APGLPGQPGS PGEQGLRGPS GDIGPKGDRG PKGAVGDTGE KGERGSPGPV
1510 1520 1530 1540 1550
GPQGLPGVAG RPGAEGPEGP PGPVGRRGEK GEPGRPGDPA VGPDGTGAKG
1560 1570 1580 1590 1600
EKGDVGPTGP RGAAGVKGER GPPGLVLPGD PGPKGDPGDR GPIGLSGRAG
1610 1620 1630 1640 1650
PPGDSGPPGE KGDPGRPGSP GPIGPRGRDG EVGEKGDEGP PGDPGLPGKA
1660 1670 1680 1690 1700
GERGLRGAPG ARGPVGEKGD QGDPGEDGRN GSPGPSGPKG DRGEPGPPGL
1710 1720 1730 1740 1750
PGRLVDSGLG AGEKGEPGDR GQEGPRGPKG DPGPPGASGE RGVSGLRGPP
1760 1770 1780 1790 1800
GPQGDPGVRG PTGEKGDRGP PGLDGRSGLD GKPGAPGPPG PHGATGKAGD
1810 1820 1830 1840 1850
PGRDGLPGLR GEHGPPGPPG PPGIQGKPGE DGKPGLNGKN GEPGDPGEDG
1860 1870 1880 1890 1900
RKGEKGDSGA PGREGHDGPK GERGAPGSPG LQGPPGLPGQ MGPSGQGFPG
1910 1920 1930 1940 1950
VPGNTGPKGD RGDTGPKGEQ GLPGERGLRG DPGSVGNVER LLETIGIKTS
1960 1970 1980 1990 2000
ALREIVETWD ESSGSFLPMP ERRRGPKGDP GERGPPGKEG PIGFSGERGL
2010 2020 2030 2040 2050
KGERGDPGPQ GPPGLALGER GPPGPPGLAG EPGKPGIPGL PGRAGGAGEA
2060 2070 2080 2090 2100
GRPGERGERG EKGERGEQGR DGPPGLPGPP GPPGPKVAVD EPGPGLSGVQ
2110 2120 2130 2140 2150
GPPGFKGAKG EPGSDGDQGP KGDRGMPGIK GDRGEPGQKG LDGSPGLPGE
2160 2170 2180 2190 2200
RGVAGPEGKP GLQGPRGTPG PVGGHGDPGP PGAPGLAGPA GPQGPSGLKG
2210 2220 2230 2240 2250
EPGETGPPGR GLPGPTGAVG LPGPPGPSGL VGPQGAPGLP GQVGETGKPG
2260 2270 2280 2290 2300
APGRDGAGGK DGDRGAPGVP GSPGLPGPVG PKGEPGQTGT PGQAVVGPPG
2310 2320 2330 2340 2350
AKGEKGAPGG LAGDLVGEPG AKGDRGLPGP RGEKGEAGRA GEPGDPGEDG
2360 2370 2380 2390 2400
QKGAPGLKGN KGDPGVGVEG PPGPAGLPGV KGDVGPPGSP GAPGVVGFPG
2410 2420 2430 2440 2450
QTGPRGEMGQ PGPSGERGLA GLPGREGPPG PLGPPGPPGS TGVPGASGPK
2460 2470 2480 2490 2500
GDKGDSGVGL PGARGERGEP GVRGEDGRPG QEGPRGLTGP PGSRGERGEK
2510 2520 2530 2540 2550
GDAGTSGLKG DKGDAALAMG APGPRGAKGD MGERGLPGID GDKGPRGDTG
2560 2570 2580 2590 2600
NPGEKGTKGE PGDKGSAGLL GARGLTGPKG EPGAAGIPGD PGSPGKDGTP
2610 2620 2630 2640 2650
GVRGDKGDTG FMGPRGLKGE RGVKGACGLD GEKGDKGEGG PPGRPGLAGR
2660 2670 2680 2690 2700
KGDMGEPGVP GQSGAPGKEG LIGPKGDRGF DGQPGSKGDQ GEKGERGPPG
2710 2720 2730 2740 2750
IGGFPGPRGN DGSSGPPGPP GSVGPKGPEG LQGQKGERGP PGEKMVGAPG
2760 2770 2780 2790 2800
APGTPGERGE QGRPGPAGPR GEKGEAALTE DDIRAFVRQE MSQHCACQGQ
2810 2820 2830 2840 2850
FIASGSRPLP SYAADTAGPQ LPPVPVLRVS HAEEEGQVPP EDDEYEYSEY
2860 2870 2880 2890 2900
SVEEYQDPEA PQDGNDPCLL PLDEGSCTAY TLRWYHRAVA SGTEACHPFV
2910 2920 2930
YGGCGGNANR FGTREACEHR CRPHMVQNQG TGAARS
Length:2,936
Mass (Da):293,981
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i06305FA30E808DCC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AAEX03012233 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_005632359.1, XM_005632302.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSCAFT00000019781; ENSCAFP00000018349; ENSCAFG00000012403

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
403467

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03012233 Genomic DNA No translation available.
RefSeqiXP_005632359.1, XM_005632302.2

3D structure databases

SMRiF1PIP7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9612.ENSCAFP00000018349

Protein family/group databases

MEROPSiI02.967

Proteomic databases

PaxDbiF1PIP7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000019781; ENSCAFP00000018349; ENSCAFG00000012403
GeneIDi403467

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1294
VGNCiVGNC:39483 COL7A1

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410ZJNQ LUCA
GeneTreeiENSGT00940000154865
InParanoidiF1PIP7
OMAiYRVSWHS
OrthoDBi67372at2759
TreeFamiTF351645

Enzyme and pathway databases

ReactomeiR-CFA-1442490 Collagen degradation
R-CFA-1474244 Extracellular matrix organization
R-CFA-1650814 Collagen biosynthesis and modifying enzymes
R-CFA-2022090 Assembly of collagen fibrils and other multimeric structures
R-CFA-204005 COPII-mediated vesicle transport
R-CFA-216083 Integrin cell surface interactions
R-CFA-2214320 Anchoring fibril formation
R-CFA-3000157 Laminin interactions
R-CFA-5694530 Cargo concentration in the ER
R-CFA-8948216 Collagen chain trimerization

Gene expression databases

BgeeiENSCAFG00000012403 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Family and domain databases

CDDicd00063 FN3, 9 hits
cd00109 KU, 1 hit
Gene3Di2.60.40.10, 9 hits
3.40.50.410, 2 hits
4.10.410.10, 1 hit
InterProiView protein in InterPro
IPR008160 Collagen
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF01391 Collagen, 10 hits
PF00041 fn3, 9 hits
PF00014 Kunitz_BPTI, 1 hit
PF00092 VWA, 2 hits
PRINTSiPR00759 BASICPTASE
SMARTiView protein in SMART
SM00060 FN3, 9 hits
SM00327 VWA, 1 hit
SUPFAMiSSF49265 SSF49265, 6 hits
SSF53300 SSF53300, 2 hits
SSF57362 SSF57362, 1 hit
PROSITEiView protein in PROSITE
PS00280 BPTI_KUNITZ_1, 1 hit
PS50279 BPTI_KUNITZ_2, 1 hit
PS50853 FN3, 9 hits
PS50234 VWFA, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1PIP7_CANLF
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1PIP7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: May 8, 2019
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again