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Protein
Submitted name:

Steroid hormone receptor ERR1

Gene

ESRRA

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi267 – 342Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-CFA-383280 Nuclear Receptor transcription pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Steroid hormone receptor ERR1Imported
Gene namesi
Name:ESRRAImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 18

Organism-specific databases

VGNCiVGNC:54270 ESRRA

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSCAFG00000014455

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini267 – 342Nuclear receptorInterPro annotationAdd BLAST76
Domaini383 – 611NR LBDInterPro annotationAdd BLAST229

Sequence similaritiesi

Belongs to the nuclear hormone receptor family. NR3 subfamily.UniRule annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118887
OMAiCHPGHKE
OrthoDBiEOG091G0DYP
TreeFamiTF323751

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR027289 Oest-rel_rcp
IPR024178 Oest_rcpt/oest-rel_rcp
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PIRSFiPIRSF002527 ER-like_NR, 1 hit
PIRSF500939 ERR1-2-3, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 2 hits
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

F1PFF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVSPCPAAA AAEPPRPLLS RAARPAPRYV RPPLVPTPPR SLQVSAGLAP
60 70 80 90 100
QPPPSPVRRP GSAAVGGALA KVRPLAPPAP PRPVRARRRR RSTCLISIER
110 120 130 140 150
QGPPPALHAQ AGPTPAVSWR KQSRKRPRCP FVSYKPPAAP PSEGTRRGGA
160 170 180 190 200
VRPEEAAEEG PFAAPGSPRR SGPLGPHACQ PASPEPQVTS AMSSQVVGIE
210 220 230 240 250
PLYIKAEPAS PDSPKGSSET ETEPPVALAP GPAPTRCLPG HKEEEDGEGA
260 270 280 290 300
GPGEQGGGKL VLSSLPKRLC LVCGDVASGY HYGVASCEAC KAFFKRTIQG
310 320 330 340 350
SIEYSCPASN ECEITKRRRK ACQACRFTKC LRVGMLKEGV RLDRVRGGRQ
360 370 380 390 400
KYKRRPEVDP LPFPGSFPAG PLAVAGGPRK TAPVNALVSH LLVVEPEKLY
410 420 430 440 450
AMPDPAGPDG HLPAVATLCD LFDREIVVTI SWAKSIPGFS SLSLSDQMSV
460 470 480 490 500
LQSVWMEVLV LGVAQRSLPL QDELAFAEDL VLDEEGARAA GLGELGAALL
510 520 530 540 550
QLVRRLQALR LEREEYVLLK ALALANSDSV HIEDAEAVEQ LREALHEALL
560 570 580 590 600
EYEAGRAGPG GGAERRRAGR LLLTLPLLRQ TAGKVLAHFY GVKLEGKVPM
610
HKLFLEMLEA MMD
Length:613
Mass (Da):65,350
Last modified:October 31, 2012 - v2
Checksum:i2906EA317917A9B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03011644 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000022969; ENSCAFP00000021334; ENSCAFG00000014455

Similar proteinsi

Entry informationi

Entry nameiF1PFF7_CANLF
AccessioniPrimary (citable) accession number: F1PFF7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: July 18, 2018
This is version 64 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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