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Protein
Submitted name:

Unc-5 netrin receptor A

Gene

UNC5A

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-373752 Netrin-1 signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Unc-5 netrin receptor AImported
Gene namesi
Name:UNC5AImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 4

Organism-specific databases

VGNCiVGNC:48139 UNC5A

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei324 – 348HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1P899

Expressioni

Gene expression databases

BgeeiENSCAFG00000016621

Interactioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000024468

Structurei

3D structure databases

ProteinModelPortaliF1P899
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 199Ig-likeInterPro annotationAdd BLAST80
Domaini552 – 695ZU5InterPro annotationAdd BLAST144

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1480 Eukaryota
ENOG410XRS6 LUCA
GeneTreeiENSGT00920000149006
InParanoidiF1P899
OMAiGTSNMTY
OrthoDBiEOG091G040Q
TreeFamiTF316767

Family and domain databases

Gene3Di2.20.100.10, 2 hits
2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR000884 TSP1_rpt
IPR036383 TSP1_rpt_sf
IPR037936 UNC5
IPR033772 UPA
IPR000906 ZU5_dom
PANTHERiPTHR12582 PTHR12582, 1 hit
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF07679 I-set, 1 hit
PF00090 TSP_1, 2 hits
PF17217 UPA, 1 hit
PF00791 ZU5, 1 hit
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SM00409 IG, 1 hit
SM00209 TSP1, 2 hits
SM00218 ZU5, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF48726 SSF48726, 2 hits
SSF82895 SSF82895, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit
PS50092 TSP1, 2 hits
PS51145 ZU5, 1 hit

Sequencei

Sequence statusi: Complete.

F1P899-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PGANPDLLPH FLVEPEDVYI VKNKPVLLVC KALPATQIFF KCNGEWVRQV
60 70 80 90 100
DHVIERSTDD SSGLPAMEVR INVSRQQVEK VFGLEEYWCQ CVAWSSSGTT
110 120 130 140 150
KSQKAYIRIA YLRKNFEQEP LAKEVSLEQG IVLPCRPPEG IPPAEVEWLR
160 170 180 190 200
NEDLVDPSLD PNVYITREHS LVVRQARLAD TANYTCVAKN IVARRRSASA
210 220 230 240 250
AVIVYVNGGW STWTEWSVCS ASCGRGWQKR SRSCTNPAPL NGGAFCEGQN
260 270 280 290 300
VQKTACATLC PVDGSWSPWS KWSACGLDCT HWRSRECSDP APRNGGEECR
310 320 330 340 350
GTDLDTRNCT SDLCVHTASR PEDVALYVGL IAVAVCLLLL LLVLILVYCR
360 370 380 390 400
KKEGLDSDVA DSSILTSGFQ PVSIKPSKAD NPHLLTIQPD LSTTTTTCQG
410 420 430 440 450
SLCPRQDGTS PKFQLANGHL LSPLSGGRHT LHHSSPTSEA EDFVSRLSTQ
460 470 480 490 500
NYFRSLPRGT SNMTYGTFNF LGGRLMIPNT GLLSIHLCGQ PALYSTLWAE
510 520 530 540 550
KAAGKAVGAR GEGLKCQTRK PGLMLESGEC PGLTQCLLGD RSGRYSIPGT
560 570 580 590 600
FLFHSFLCPG QRGMLFHSVT GISLLIPPDA IPRGKIYEIY LTLHKPEDVR
610 620 630 640 650
LPLAGCQTLL SPIVSCGPPG VLLTRPVILA MDHCGEPCPE SWSLRLKKQS
660 670 680 690 700
CEGSWEDVLH LGEEAPSHLY YCQLEAGACY VFTEQLGRFA LVGEALSVAA
710 720 730 740 750
TKRLKLLLFA PVACTSLEYN IRVYCLHDTH DALKEVVQLE KQLGGQLIQE
760 770 780 790 800
PRVLHFKDSY HNLRLSIHDV PSSLWKSKLL VSYQEIPFYH IWNGTQQYLH
810 820 830 840 850
CAFTLERVSP STSDLACKVW VWQVEGDGQS FNINFNITKD TRFAELLALE
860 870 880 890 900
SEGGVPALVG PSAFKIPFLI RQKIITSLDP PCSRGADWRT LAQKLHLDSH
910 920 930 940 950
LSFFASKPSP TAMILNLWEA RHFPNGNLSQ LAAAVAGLGQ PDAGLFTVSE

A
Length:951
Mass (Da):104,670
Last modified:October 31, 2012 - v2
Checksum:iA3A2D69DF92F3D56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03002972 Genomic DNA No translation available.
AAEX03002973 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000026346; ENSCAFP00000024468; ENSCAFG00000016621

Similar proteinsi

Entry informationi

Entry nameiF1P899_CANLF
AccessioniPrimary (citable) accession number: F1P899
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: June 20, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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