Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Interleukin 1 receptor associated kinase 3

Gene

IRAK3

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-CFA-9020702 Interleukin-1 signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin 1 receptor associated kinase 3Imported
Gene namesi
Name:IRAK3Imported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Chromosome 10

Organism-specific databases

VGNCiVGNC:54151 IRAK3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1P664

Expressioni

Gene expression databases

BgeeiENSCAFG00000000374 Expressed in 3 organ(s), highest expression level in liver

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000000535

Structurei

3D structure databases

ProteinModelPortaliF1P664
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 360Protein kinaseInterPro annotationAdd BLAST288

Phylogenomic databases

eggNOGiKOG1187 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00530000063073
InParanoidiF1P664
OMAiLQEMGHH
OrthoDBiEOG091G0YKT
TreeFamiTF328924

Family and domain databases

InterProiView protein in InterPro
IPR033610 IRAK3
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
PANTHERiPTHR24419:SF7 PTHR24419:SF7, 1 hit
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

F1P664-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGHHRAIHLI VNYGAALNPS EQSHQRDGFP NMLPKETANV TTDNVLTPKH
60 70 80 90 100
NEKGILFKSS ISFQNIRDGT KNFHKDFLIG EGEIFEVYRA EIQNRTYAIK
110 120 130 140 150
LFKQEKKMQC KKQWKRFLSE LEVLLLFHHP NILELAAYFT ENEKFCLVYP
160 170 180 190 200
YMRNGSLSDR LQCVGNTAPL SWHIRISVLL GTARAIQYLH NTEPCSVICG
210 220 230 240 250
SVSSANILLD DQFQPKLTDF GMAHFRPHLE HQSCTISVAS SSSKHLWYMP
260 270 280 290 300
EEYIRQGKLS IKTDVYSFGI VIMEVLTGCK VVLDDPKHIQ LRDLLMELME
310 320 330 340 350
KRGLDSCLSF LDKKVHPCPR NFSAKLFSLA GQCATSRAKL RPSMDEVLTT
360 370 380 390 400
LESTQASLYF AEDPPTSLKS FRCPSPLFLE NVPSIPVEDD ENQNNHSLPH
410 420 430 440 450
DKGLRKVGVT QKVPFECSQS EVTFLGFDRK TGSERNEDTC DRPSSSCKES
460 470 480 490 500
GSPKHVALSQ DPGAYGTDVD PSVEAPGHSY RSRPVETSCS CEFSWNECEQ
510
YKRESISPDD KEESK
Length:515
Mass (Da):58,310
Last modified:October 31, 2012 - v2
Checksum:i220F52993D032032
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03007019 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSCAFT00000000586; ENSCAFP00000000535; ENSCAFG00000000374

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAEX03007019 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF1P664
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000000535

Proteomic databases

PaxDbiF1P664

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCAFT00000000586; ENSCAFP00000000535; ENSCAFG00000000374

Organism-specific databases

VGNCiVGNC:54151 IRAK3

Phylogenomic databases

eggNOGiKOG1187 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00530000063073
InParanoidiF1P664
OMAiLQEMGHH
OrthoDBiEOG091G0YKT
TreeFamiTF328924

Enzyme and pathway databases

ReactomeiR-CFA-9020702 Interleukin-1 signaling

Gene expression databases

BgeeiENSCAFG00000000374 Expressed in 3 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR033610 IRAK3
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
PANTHERiPTHR24419:SF7 PTHR24419:SF7, 1 hit
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1P664_CANLF
AccessioniPrimary (citable) accession number: F1P664
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: October 31, 2012
Last modified: November 7, 2018
This is version 51 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again