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Protein
Submitted name:

Uncharacterized protein

Gene

SLC25A12

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi171 – 182PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransportUniRule annotationSAAS annotation
LigandCalciumPROSITE-ProRule annotation

Enzyme and pathway databases

ReactomeiR-GGA-70263 Gluconeogenesis

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SLC25A12Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF1P3D8

Expressioni

Gene expression databases

BgeeiENSGALG00000009545 Expressed in 11 organ(s), highest expression level in skeletal muscle tissue
ExpressionAtlasiF1P3D8 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000015519

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 122EF-handInterPro annotationAdd BLAST36
Domaini158 – 193EF-handInterPro annotationAdd BLAST36
Repeati326 – 418SolcarPROSITE-ProRule annotationAdd BLAST93
Repeati426 – 510SolcarPROSITE-ProRule annotationAdd BLAST85
Repeati518 – 606SolcarPROSITE-ProRule annotationAdd BLAST89

Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG0751 Eukaryota
ENOG410XNRM LUCA
GeneTreeiENSGT00530000062944
InParanoidiF1P3D8
OrthoDBiEOG091G08GT
TreeFamiTF313209

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
PS50920 SOLCAR, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F1P3D8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAVKQVPSTK RADPAELRSI FLQYASVEKD GEHYMTPEDF VQKYLGLYTD
60 70 80 90 100
PRYNPKTVQL LAGVADQTKD GLISFQEFLA FESVLCTPDA IFIVAFQLFD
110 120 130 140 150
KSGNGEVTFA NVKEVFEQTT THHQIPFNWD CEFIRLHFGH NRKKHLNYTE
160 170 180 190 200
FTQFLQELQS EHARQAFSLK DKNKSGMITG LDFRDVMVTL HSHMLTPFVE
210 220 230 240 250
ENLVSVAGGT VSHQVSFSYF NAFNALLNNM DLVRKIYSNI AGTRKDVEVT
260 270 280 290 300
KEEFTQSAIR FGQVTPLEID ILYQLTGLYS VTGRLTLADI ERVAPLAEGA
310 320 330 340 350
LPYNLAELQR QQSFGELSRP IWLQVAESAY RFTLGSIAGA VGATAVYPID
360 370 380 390 400
LVKTRMQNQR STGSVVGELM YKNSFDCFKK VLRFEGFFGL YRGLLPQLIG
410 420 430 440 450
VAPEKAIKLT VNDFVRDKFT KKDGSIPLPA EILAGGCAGA SQVIFTNPLE
460 470 480 490 500
IVKIRLQVAG EITTGPRVSA LSVMKDLGLL GLYKGAKACF LRDIPFSAIY
510 520 530 540 550
FPVYAHSKLM LADENGHVGG LNLLAAGAIA GVPAASLVTP ADVIKTRLQV
560 570 580 590 600
AARAGQTTYS GVIDCFGKIL REEGPSAFWK GAAARVFRSS PQFGVTLVTY
610 620 630 640 650
ELLQRWFYVD FGGLKPSGSE PTPKTRISDL PPVNPEHIGG YRLATATFAD

FRLKVKD
Length:657
Mass (Da):72,693
Last modified:November 30, 2016 - v3
Checksum:i122883BAD64EC0F5
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D5PP62A0A1D5PP62_CHICK
Uncharacterized protein
SLC25A12
675Annotation score:
A0A1D5PSJ5A0A1D5PSJ5_CHICK
Solute carrier family 25 member 12
SLC25A12
321Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000247 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSGALT00000015535; ENSGALP00000015519; ENSGALG00000009545

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000247 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000015519

Proteomic databases

PaxDbiF1P3D8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000015535; ENSGALP00000015519; ENSGALG00000009545

Phylogenomic databases

eggNOGiKOG0751 Eukaryota
ENOG410XNRM LUCA
GeneTreeiENSGT00530000062944
InParanoidiF1P3D8
OrthoDBiEOG091G08GT
TreeFamiTF313209

Enzyme and pathway databases

ReactomeiR-GGA-70263 Gluconeogenesis

Gene expression databases

BgeeiENSGALG00000009545 Expressed in 11 organ(s), highest expression level in skeletal muscle tissue
ExpressionAtlasiF1P3D8 baseline and differential

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SMARTiView protein in SMART
SM00054 EFh, 3 hits
SUPFAMiSSF103506 SSF103506, 1 hit
SSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
PS50920 SOLCAR, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiF1P3D8_CHICK
AccessioniPrimary (citable) accession number: F1P3D8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: November 30, 2016
Last modified: October 10, 2018
This is version 53 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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