UniProtKB - F1N0Y1 (F1N0Y1_BOVIN)
Protein
Submitted name:
Scribble planar cell polarity protein
Gene
SCRIB
Organism
Bos taurus (Bovine)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Scribble planar cell polarity proteinImported |
Gene namesi | Name:SCRIBImported |
Organismi | Bos taurus (Bovine)Imported |
Taxonomic identifieri | 9913 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:34365, SCRIB |
Expressioni
Gene expression databases
Bgeei | ENSBTAG00000008421, Expressed in skeletal muscle tissue and 18 other tissues |
ExpressionAtlasi | F1N0Y1, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 716 – 803 | PDZInterPro annotationAdd BLAST | 88 | |
Domaini | 850 – 938 | PDZInterPro annotationAdd BLAST | 89 | |
Domaini | 986 – 1075 | PDZInterPro annotationAdd BLAST | 90 | |
Domaini | 1082 – 1170 | PDZInterPro annotationAdd BLAST | 89 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 452 – 601 | DisorderedSequence analysisAdd BLAST | 150 | |
Regioni | 633 – 690 | DisorderedSequence analysisAdd BLAST | 58 | |
Regioni | 820 – 847 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 938 – 969 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 1241 – 1264 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 1284 – 1438 | DisorderedSequence analysisAdd BLAST | 155 | |
Regioni | 1465 – 1578 | DisorderedSequence analysisAdd BLAST | 114 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 460 – 496 | PolyampholyteSequence analysisAdd BLAST | 37 | |
Compositional biasi | 562 – 586 | PolyampholyteSequence analysisAdd BLAST | 25 | |
Compositional biasi | 658 – 678 | AcidicSequence analysisAdd BLAST | 21 | |
Compositional biasi | 941 – 968 | Pro-richSequence analysisAdd BLAST | 28 | |
Compositional biasi | 1250 – 1264 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 1332 – 1353 | PolyampholyteSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the LAP (LRR and PDZ) protein family.ARBA annotation
Keywords - Domaini
Leucine-rich repeatARBA annotation, RepeatARBA annotationPhylogenomic databases
eggNOGi | KOG0619, Eukaryota |
GeneTreei | ENSGT00940000154025 |
HOGENOMi | CLU_000288_18_20_1 |
InParanoidi | F1N0Y1 |
OMAi | NNFHPKQ |
TreeFami | TF351429 |
Family and domain databases
Gene3Di | 2.30.42.10, 4 hits 3.80.10.10, 3 hits |
InterProi | View protein in InterPro IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR001478, PDZ IPR036034, PDZ_sf |
Pfami | View protein in Pfam PF13855, LRR_8, 2 hits PF00595, PDZ, 4 hits |
SMARTi | View protein in SMART SM00369, LRR_TYP, 12 hits SM00228, PDZ, 4 hits |
SUPFAMi | SSF50156, SSF50156, 4 hits |
PROSITEi | View protein in PROSITE PS51450, LRR, 13 hits PS50106, PDZ, 4 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
F1N0Y1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKCIPLWRC NRHVESVDKR HCSLQAVPEE IYRYSRSLEE LLLDANQLRE
60 70 80 90 100
LPKPFFRLLN LRKLGLSDNE IQRLPPEVAN FMQLVELDVS RNDIPEIPES
110 120 130 140 150
IKFCKALEIA DFSGNPLSRL PEGFTQLRSL AHLALNDVSL QALPGDVGNL
160 170 180 190 200
ANLVTLELRE NLLKSLPASL SFLVKLEQLD LGGNDLEVLP DTLGALPNLR
210 220 230 240 250
ELWLDRNQLS ALPPELGNLR RLVCLDVSEN RLEELPAELG GLVLLTDLLL
260 270 280 290 300
SQNLLQRLPD GIGQLKQLSI LKVDQNRLCE VTEAIGDCEN LSELILTENL
310 320 330 340 350
LTALPHSLGK LTKLTNLNVD RNHLEALPPE IGGCVALSVL SLRDNRLAVL
360 370 380 390 400
PPELAHTAEL HVLDVAGNRL QSLPFALTHL NLKALWLAEN QAQPMLRFQT
410 420 430 440 450
EDDAQTGEKV LTCYLLPQQP LPSLEDPELQ SSPSESWGDA PLSRVSVIQF
460 470 480 490 500
LEAPAGDDDP EEAAAEKRGL QRRATPHPSE LKVMKRGVER RSEATSCRPD
510 520 530 540 550
PAPPSPSEEE KRLSTESGLS ADSHLSAGTV SQGEPEGPLA EEEGLSQQEP
560 570 580 590 600
MPATQEEVME ETYEEPTVRF AEDTLLLPRE DGESEEGQPE APWPLPGGRQ
610 620 630 640 650
RLIRKDTPHY KKHFKISKLP QPEAVVALLQ GTPPDNEGPV GTGGWHNGPH
660 670 680 690 700
MSWAPRAEEE EEEEEDEAEE EEEGEAAAAA EEEKAVASAP SVKGVSFDQA
710 720 730 740 750
NNLLIEPARI EEEELTLTIV RQTGGLGISI AGGKGSTPYK GDDEGIFISR
760 770 780 790 800
VSEEGPAARA GVRVGDKLLE VNGVALQDAE HQQAVEALRG AGATVHMRLW
810 820 830 840 850
RERMVEPENA VTVTALRPED DYSPRERRGG GLRLPLLPPE PPGPPRQRHV
860 870 880 890 900
ACLVRSEKGL GFSIAGGKGS TPYRAGDGGI FISRIAEGGA AHRAGTLQVG
910 920 930 940 950
DRVLSINGVD MTEARHDHAV SLLTAASPTI ALLLEREAGG PLAPSPPPHS
960 970 980 990 1000
PPPPTATPAT PGEPGPLRLP PSLLAAALEG PYPVEEICLP RAGGPLGLSI
1010 1020 1030 1040 1050
VGGSDHSSHP FGVQEPGVFI SKVLPRGLAA RSGLRVGDRI LAVNGQDVRE
1060 1070 1080 1090 1100
ATHQEAVSAL LRPCLELVLL VRRDPPPPGM RELCIQKAPG ERLGISIRGG
1110 1120 1130 1140 1150
AKGHAGNPCD PTDEGIFISK VSPTGAAGRD GRLRVGLRLL EVNQQSLLGL
1160 1170 1180 1190 1200
THGEAVQLLR SVGDTLTVLV CDGFDTSAAT PEVSPGIIAN PFAAGLGRRN
1210 1220 1230 1240 1250
SLESISSIDR ELSPEGPGKE KELPGQIPLW GPEAMVLPAA SGEMAEPPCS
1260 1270 1280 1290 1300
PSHQQPPSPP SPAELPANVK QAYRTFAAVP GLHPPLDTPA QHPMLGPTAS
1310 1320 1330 1340 1350
PEQLSFRERQ KYFELEVRVP QAEGPPKRVS LVGADDLRKM QEEEARKLQQ
1360 1370 1380 1390 1400
KRAQMLREAA ANTGLPEADA PEDEEPEEEP PWAGQGPMAE GLGPASPPPQ
1410 1420 1430 1440 1450
GGGAPVRTAK AERRHQERLR VQSPELPAPE RALSPAERRA LEAEKRALWR
1460 1470 1480 1490 1500
AARMKSLEQD ALRAQMVLSK SQDGRSKRGP LERLAEAPSP APTPSPTPLE
1510 1520 1530 1540 1550
DLGPQTGTSP GRLSPDFAEE LRSLEPPPSP GLPEEDGEVA MVLLGRPSPS
1560 1570
STGPEEVALC SSRRAVRPGR RGLGPVPS
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q1LUY1 | A0A3Q1LUY1_BOVIN | Scribble planar cell polarity prote... | SCRIB | 1,603 | Annotation score: | ||
A0A3Q1MAJ4 | A0A3Q1MAJ4_BOVIN | Scribble planar cell polarity prote... | SCRIB | 1,541 | Annotation score: |
Genome annotation databases
Ensembli | ENSBTAT00000011082; ENSBTAP00000011082; ENSBTAG00000008421 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9913.ENSBTAP00000011082 |
Proteomic databases
PaxDbi | F1N0Y1 |
PRIDEi | F1N0Y1 |
Genome annotation databases
Ensembli | ENSBTAT00000011082; ENSBTAP00000011082; ENSBTAG00000008421 |
Organism-specific databases
VGNCi | VGNC:34365, SCRIB |
Phylogenomic databases
eggNOGi | KOG0619, Eukaryota |
GeneTreei | ENSGT00940000154025 |
HOGENOMi | CLU_000288_18_20_1 |
InParanoidi | F1N0Y1 |
OMAi | NNFHPKQ |
TreeFami | TF351429 |
Gene expression databases
Bgeei | ENSBTAG00000008421, Expressed in skeletal muscle tissue and 18 other tissues |
ExpressionAtlasi | F1N0Y1, baseline and differential |
Family and domain databases
Gene3Di | 2.30.42.10, 4 hits 3.80.10.10, 3 hits |
InterProi | View protein in InterPro IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR001478, PDZ IPR036034, PDZ_sf |
Pfami | View protein in Pfam PF13855, LRR_8, 2 hits PF00595, PDZ, 4 hits |
SMARTi | View protein in SMART SM00369, LRR_TYP, 12 hits SM00228, PDZ, 4 hits |
SUPFAMi | SSF50156, SSF50156, 4 hits |
PROSITEi | View protein in PROSITE PS51450, LRR, 13 hits PS50106, PDZ, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1N0Y1_BOVIN | |
Accessioni | F1N0Y1Primary (citable) accession number: F1N0Y1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | April 7, 2021 | |
This is version 77 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |