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Protein
Submitted name:

Chromosome-associated kinesin KIF4A

Gene

KIF4A

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi91 – 98ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-BTA-2132295 MHC class II antigen presentation
R-BTA-437239 Recycling pathway of L1
R-BTA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-BTA-983189 Kinesins

Names & Taxonomyi

Protein namesi
Submitted name:
Chromosome-associated kinesin KIF4AImported
Gene namesi
Name:KIF4AImported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1MCP5

Expressioni

Gene expression databases

BgeeiENSBTAG00000012861 Expressed in 8 organ(s), highest expression level in spleen

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000017093

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 340Kinesin motorInterPro annotationAdd BLAST329

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili389 – 409Sequence analysisAdd BLAST21
Coiled coili424 – 444Sequence analysisAdd BLAST21
Coiled coili530 – 550Sequence analysisAdd BLAST21
Coiled coili558 – 657Sequence analysisAdd BLAST100
Coiled coili690 – 724Sequence analysisAdd BLAST35
Coiled coili768 – 788Sequence analysisAdd BLAST21
Coiled coili824 – 851Sequence analysisAdd BLAST28
Coiled coili913 – 933Sequence analysisAdd BLAST21
Coiled coili942 – 962Sequence analysisAdd BLAST21
Coiled coili971 – 1005Sequence analysisAdd BLAST35

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0244 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00910000143992
InParanoidiF1MCP5
OMAiKEINEGC
OrthoDBiEOG091G02I4
TreeFamiTF105224

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR033467 Tesmin/TSO1-like_CXC
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM01114 CXC, 1 hit
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

F1MCP5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SRIMKEEVKG IPVRVALRCR PLVPKEINEG CQMCLSFVPG EPQVVVGTDK
60 70 80 90 100
SFTYDFVFDP STEQEEVFNT AVAPLIKGVF KGYNATVLAY GQTGSGKTYS
110 120 130 140 150
MGGAYTAEQE NEPTVGVIPR VIQLLFKEID KKSDFEFTLK VSYLEIYNEE
160 170 180 190 200
ILDLLCPSRE KAPQINIRED PKEGIKIMGL TEKTVFIALD TVSCLEQGNN
210 220 230 240 250
CRTVASTAMN SQSSRSHAIF TISIEQRKKS DKNSSFRSKL HLVDLAGSER
260 270 280 290 300
QKKTKAEGDR LKEGININRG LLCLGNVISA LGDDKKCGFV PYRDSKLTRL
310 320 330 340 350
LQDSLGGNSH TLMIACVSPA DSNLEETLNT LRYADRARKI KNKPVVNIDP
360 370 380 390 400
QTAELNHLKQ QVQQLQVLLL QAHGGTLPGS INVEPSENLQ SLMEKNQSLV
410 420 430 440 450
EENEKLSRGL SEAAGQTAQM LERIILTEQA NEKMNAKLEE LRKHAACKVD
460 470 480 490 500
LQKLVETLED QELKENVEII RNLQQVITQL SDETVACMTA AIDTAVEPET
510 520 530 540 550
QEADSPDSSR SSDAFTTQHA LRQAQMSKEL VELNKALALK EALAKKMTQN
560 570 580 590 600
DNQLQPIHFQ YQDNIKNLEL EVINLQKEKE ELVLELQTAK KDVNQAKLSE
610 620 630 640 650
RRRKRLQELE GQIADLKKKL NEQSKLLKLK ESTEHTVSKL NQEIRVIKNQ
660 670 680 690 700
RVQLMRQMKE DAERFRQWKQ QKDKEVIQLK ERDRKRQYEL LKLERNFQKQ
710 720 730 740 750
SNVLRRKTEE AAAANKRLKD ALQKQREVAD KRKESQSRGM EGTAARVKSW
760 770 780 790 800
LGNEIEIMVS TEEAKRHLND LLEDRKILAQ DVAQLKLKME SGENPPPKLR
810 820 830 840 850
RRTFSLAELR GQVPASEDSI KKQIESLETE MELRSAQIAD LQQKLLDAES
860 870 880 890 900
EDRLKHRWEN IATILEAKCA LKYLTGELVS SKIQVSKLES NLKQNKASHA
910 920 930 940 950
DMQKMLFEER NHFAEIEAEL QAELVRMEQQ HQERVLYLLS QLQQSQMAEK
960 970 980 990 1000
QLEESVSEKE QQLLNTLKCQ QDEELEKMRE VCEQNQQLLR ENELMKQKLN
1010 1020 1030 1040 1050
LLQVASKQKS HLPKDTLLSP DSSFEYIPPK PKPSRFKEKF LEQSMDIEDL
1060 1070 1080 1090 1100
KYCSEYSVNE PEDNDDDDGD GNDEEWKPTK LVKVSKKNIQ GCSCKGWCGN
1110 1120 1130 1140 1150
KQCGCRKQKL DCGADCSCDA TKCRNRQQDK DSLGTVERTQ DSEGSFKLED
1160 1170 1180 1190 1200
PTEVTPGLSF FNPVCATPNS KILKEMSDEE QVLLKKTAPA ASSLGLSESK
1210 1220 1230
DVATETQGNK APGKKKKRAL ASNTSFFSGC SPIEEEAH
Length:1,238
Mass (Da):140,452
Last modified:May 3, 2011 - v1
Checksum:i6F74A84B6ABF8190
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02072849 Genomic DNA No translation available.
DAAA02072850 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSBTAT00000017093; ENSBTAP00000017093; ENSBTAG00000012861

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02072849 Genomic DNA No translation available.
DAAA02072850 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000017093

Proteomic databases

PaxDbiF1MCP5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSBTAT00000017093; ENSBTAP00000017093; ENSBTAG00000012861

Phylogenomic databases

eggNOGiKOG0244 Eukaryota
COG5059 LUCA
GeneTreeiENSGT00910000143992
InParanoidiF1MCP5
OMAiKEINEGC
OrthoDBiEOG091G02I4
TreeFamiTF105224

Enzyme and pathway databases

ReactomeiR-BTA-2132295 MHC class II antigen presentation
R-BTA-437239 Recycling pathway of L1
R-BTA-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-BTA-983189 Kinesins

Gene expression databases

BgeeiENSBTAG00000012861 Expressed in 8 organ(s), highest expression level in spleen

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
IPR033467 Tesmin/TSO1-like_CXC
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM01114 CXC, 1 hit
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1MCP5_BOVIN
AccessioniPrimary (citable) accession number: F1MCP5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 12, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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