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Protein
Submitted name:

Serine protease inhibitor A3F-like

Gene

LOC100909605

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • serine-type endopeptidase inhibitor activity Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-114608 Platelet degranulation
R-RNO-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
Serine protease inhibitor A3F-likeImported
Gene namesi
Name:LOC100909605Imported
Synonyms:RGD1565462Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi6502633 LOC100909605
1565462 RGD1565462

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiF1M8F5

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000054092

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 407SERPINInterPro annotationAdd BLAST362

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
InParanoidiF1M8F5
KOiK04525
OMAiFLMIIVP
OrthoDBiEOG091G0ION
TreeFamiTF343201

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

F1M8F5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGISPADLG CPDGKLGRDT AVQKGQDNKI QVDSSTLSSC NTDFAFSLYK
60 70 80 90 100
ELVLKNPDKN IVFSSFSIST ALVLLSLGAK NNTLKEILEG LKFNLTETPE
110 120 130 140 150
AEIHQGYEHL LQRLNLPGDQ VQISTGSALF IKKHLQILAE FQEKARALYQ
160 170 180 190 200
AEAFSTDFQQ PHEAKKLIND YVRKQTQGKI KELISVLDKK TSMVLVNYIY
210 220 230 240 250
FKGKWKMPFD PHDTFQSEFY LDEKKSVKVP MMKIEKLTTP YFRDEELSCS
260 270 280 290 300
VLELKYTGNA SALFILPDQG RMQQVEASLQ PETLRRWKDT LRPRRIDELR
310 320 330 340 350
MPKFSISTDM RLGDILPELG IREVFSQQAD LSRITGAKDL SVSQVVHKAV
360 370 380 390 400
LDVTETGTEA AAATGVKIIP MCAKFYYVTM YFNRPFLMII SDTNTHIALF
410
MAKVTNPKED
Length:410
Mass (Da):46,357
Last modified:July 22, 2015 - v3
Checksum:i605568187084ADA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07065422 Genomic DNA No translation available.
AABR07065451 Genomic DNA No translation available.
RefSeqiXP_006225932.2, XM_006225870.3
XP_006240581.2, XM_006240519.3
XP_008763125.1, XM_008764903.2

Genome annotation databases

EnsembliENSRNOT00000044152; ENSRNOP00000050666; ENSRNOG00000029949
ENSRNOT00000057271; ENSRNOP00000054092; ENSRNOG00000048191
GeneIDi100909605
299279
KEGGirno:100909605
rno:299279

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07065422 Genomic DNA No translation available.
AABR07065451 Genomic DNA No translation available.
RefSeqiXP_006225932.2, XM_006225870.3
XP_006240581.2, XM_006240519.3
XP_008763125.1, XM_008764903.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000054092

Proteomic databases

PRIDEiF1M8F5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000044152; ENSRNOP00000050666; ENSRNOG00000029949
ENSRNOT00000057271; ENSRNOP00000054092; ENSRNOG00000048191
GeneIDi100909605
299279
KEGGirno:100909605
rno:299279

Organism-specific databases

CTDi299279
RGDi6502633 LOC100909605
1565462 RGD1565462

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
InParanoidiF1M8F5
KOiK04525
OMAiFLMIIVP
OrthoDBiEOG091G0ION
TreeFamiTF343201

Enzyme and pathway databases

ReactomeiR-RNO-114608 Platelet degranulation
R-RNO-6798695 Neutrophil degranulation

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1M8F5_RAT
AccessioniPrimary (citable) accession number: F1M8F5
Secondary accession number(s): F1LVP4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 22, 2015
Last modified: November 7, 2018
This is version 53 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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