Zic5

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
RNA polymerase II regulatory region sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Zic family member 5Imported Submitted name: Zinc finger protein of the cerebellum 5 (Predicted)Imported
Gene namesⁱ	Name:Zic5Imported Synonyms:Zic5_predictedImported ORF Names:rCG_36883Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 15

Organism-specific databases

Rat genome database More...RGDⁱ	1310160 Zic5

RGDⁱ

1310160 Zic5

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	F1M349

PRIDEⁱ

F1M349

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000014358 Expressed in 5 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000014358 Expressed in 5 organ(s), highest expression level in brain

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000063030

STRINGⁱ

10116.ENSRNOP00000063030

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	65 – 92	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	93 – 122	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	123 – 152	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	153 – 182	C2H2-typeInterPro annotationAdd BLAST	30

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140802
KEGG Orthology (KO) More...KOⁱ	K09226
OMAⁱ	DEDMYAN
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0M59

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

F1M349-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRQPIKRELI CKWLDPEELA GPPAPADSGA KPCSKTFGTM HELVNHVTVE 
        60         70         80         90        100
HVGGPEQSSH VCFWEDCPRE GKPFKAKYKL INHIRVHTGE KPFPCPFPGC 
       110        120        130        140        150
GKVFARSENL KIHKRTHTGE KPFKCEFDGC DRKFANSSDR KKHSHVHTSD 
       160        170        180        190        200
KPYYCKIRGC DKSYTHPSSL RKHMKIHCKS PPPSPGALGY SSVGTPVGDT 
       210        220        230        240        250
LSPVLDPTRS RSSTLSPQVT NLNEWYVCQA GGAPSHLHTP SSNGTTSESE 
       260 
DEEMYGNPEV MRTIH

Length:265

Mass (Da):29,483

Last modified:April 3, 2013 - v2

Checksum:ⁱ0F9C060BA1C8349C

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC123185 Genomic DNA No translation available. CH473951 Genomic DNA Translation: EDM02581.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001101861.1, NM_001108391.1
UniGeneⁱ	Rn.198356

Genome annotation databases

Ensemblⁱ	ENSRNOT00000067577; ENSRNOP00000063030; ENSRNOG00000014358
GeneIDⁱ	361095
KEGGⁱ	rno:361095

Protein	Similar proteins		Species	Score	Length	Source
F1M349	Zinc finger protein ZIC 5		MOUSE		622	UniRef90_Q7TQ40
Zinc finger protein of the cerebellum 5 (Fragment)		synthetic construct		275
UPI000A311A2A		MUSPA		622
UPI000A31A2A3		MUSCR		622
UPI00038C2ED4		MICOH		617
+2

Protein	Similar proteins		Species	Score	Length	Source
F1M349	Zinc finger protein ZIC 5		MOUSE		622	UniRef50_Q7TQ40
Zinc finger protein ZIC 5		HUMAN		663
Zinc finger protein of the cerebellum 5 (Fragment)		synthetic construct		275
LOW QUALITY PROTEIN: zinc finger protein ZIC 5		Enhydra lutris kenyoni		773
Zic family member 5		CANLF		669
+64

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC123185 Genomic DNA No translation available. CH473951 Genomic DNA Translation: EDM02581.1
RefSeqⁱ	NP_001101861.1, NM_001108391.1
UniGeneⁱ	Rn.198356

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000063030

STRINGⁱ

10116.ENSRNOP00000063030

Proteomic databases

PRIDEⁱ	F1M349

PRIDEⁱ

F1M349

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000067577; ENSRNOP00000063030; ENSRNOG00000014358
GeneIDⁱ	361095
KEGGⁱ	rno:361095

Organism-specific databases

CTDⁱ	85416
RGDⁱ	1310160 Zic5

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00900000140802
KOⁱ	K09226
OMAⁱ	DEDMYAN
OrthoDBⁱ	EOG091G0M59

Gene expression databases

Bgeeⁱ	ENSRNOG00000014358 Expressed in 5 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000014358 Expressed in 5 organ(s), highest expression level in brain

Family and domain databases

InterProⁱ	View protein in InterPro IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F1M349_RAT
Accessionⁱ	F1M349Primary (citable) accession number: F1M349
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 3, 2011
	Last sequence update:	April 3, 2013
	Last modified:	November 7, 2018
	This is version 52 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F1M349 (F1M349_RAT)

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Zic family member 5

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ