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Protein
Submitted name:

Hepatocyte nuclear factor 4, gamma

Gene

Hnf4g

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatocyte nuclear factor 4, gammaImported
Submitted name:
Hepatocyte nuclear factor 4, gamma (Predicted)Imported
Gene namesi
Name:Hnf4gImported
Synonyms:Hnf4g_predictedImported
ORF Names:rCG_41459Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1310102 Hnf4g

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiF1M342

Expressioni

Gene expression databases

BgeeiENSRNOG00000008971 Expressed in 5 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiF1M342 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011890

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 94Nuclear receptorInterPro annotationAdd BLAST76
Domaini109 – 338NR LBDInterPro annotationAdd BLAST230

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4215 Eukaryota
ENOG410XQT8 LUCA
GeneTreeiENSGT00760000118948
KOiK08037
TreeFamiTF352097

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR003068 COUP_TF
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01282 COUPTNFACTOR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F1M342-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSSAPETTS MNTTDSGVNC LCAICGDRAT GKHYGASSCD GCKGFFRRSI
60 70 80 90 100
RKSHVYSCRF SRQCVVDKDK RNQCRYCRLR KCFRAGMKKE AVQNERDRIS
110 120 130 140 150
TRRSTYEGTN IPSINTLAQA EVRSCQISVP NPSASTDINV KKIASISDVC
160 170 180 190 200
ESMKQQLLVL VEWAKYIPAF CELPLDDQVA LLRAHAGEHL LLGATKRSMM
210 220 230 240 250
YKDILLLGNH YVIHRNSCEV EVSRVANRVL DELVRPFQEI QIDDNEYACL
260 270 280 290 300
KAIVFFDPDA KGLSDPGKIK NMRFQVQISL EDYINDRQYD SRGRFGELLL
310 320 330 340 350
LLPTLQSITW QMIEQIQFVK LFGMVKIDNL LQEMLLGGAA NDGGHPHHPM
360 370 380 390 400
HPHLSQDPLT GQTILLGPMS TLVHTDQIAT PETPLPSPPQ GSGQEQYKIT
410
ANQASVISHQ PLSKQKQL
Length:418
Mass (Da):46,868
Last modified:April 3, 2013 - v2
Checksum:iD7EB78482CB2C1D3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2JXJ1A0A0G2JXJ1_RAT
Hepatocyte nuclear factor 4, gamma
Hnf4g
462Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07009487 Genomic DNA No translation available.
AABR07009488 Genomic DNA No translation available.
AABR07009489 Genomic DNA No translation available.
AABR07009490 Genomic DNA No translation available.
AABR07009491 Genomic DNA No translation available.
CH473961 Genomic DNA Translation: EDM01044.1
RefSeqiNP_001102409.1, NM_001108939.1
UniGeneiRn.154763

Genome annotation databases

EnsembliENSRNOT00000011890; ENSRNOP00000011890; ENSRNOG00000008971
GeneIDi365744
KEGGirno:365744

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07009487 Genomic DNA No translation available.
AABR07009488 Genomic DNA No translation available.
AABR07009489 Genomic DNA No translation available.
AABR07009490 Genomic DNA No translation available.
AABR07009491 Genomic DNA No translation available.
CH473961 Genomic DNA Translation: EDM01044.1
RefSeqiNP_001102409.1, NM_001108939.1
UniGeneiRn.154763

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000011890

Proteomic databases

PRIDEiF1M342

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000011890; ENSRNOP00000011890; ENSRNOG00000008971
GeneIDi365744
KEGGirno:365744

Organism-specific databases

CTDi3174
RGDi1310102 Hnf4g

Phylogenomic databases

eggNOGiKOG4215 Eukaryota
ENOG410XQT8 LUCA
GeneTreeiENSGT00760000118948
KOiK08037
TreeFamiTF352097

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway

Gene expression databases

BgeeiENSRNOG00000008971 Expressed in 5 organ(s), highest expression level in adult mammalian kidney
ExpressionAtlasiF1M342 baseline and differential

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR003068 COUP_TF
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01282 COUPTNFACTOR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1M342_RAT
AccessioniPrimary (citable) accession number: F1M342
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 77 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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