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Protein
Submitted name:

GLI family zinc finger 2

Gene

Gli2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

  • prostate gland development Source: RGD
  • response to mechanical stimulus Source: RGD

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-5610787 Hedgehog 'off' state
R-RNO-5632684 Hedgehog 'on' state

Names & Taxonomyi

Protein namesi
Submitted name:
GLI family zinc finger 2Imported
Gene namesi
Name:Gli2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 13

Organism-specific databases

RGDi1309270 Gli2

PTM / Processingi

Proteomic databases

PaxDbiF1M2B7
PRIDEiF1M2B7

Expressioni

Gene expression databases

BgeeiENSRNOG00000007261 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009963

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini457 – 484C2H2-typeInterPro annotationAdd BLAST28
Domaini485 – 514C2H2-typeInterPro annotationAdd BLAST30
Domaini515 – 545C2H2-typeInterPro annotationAdd BLAST31
Domaini546 – 576C2H2-typeInterPro annotationAdd BLAST31

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00900000140802
OMAiVVQYIKS
OrthoDBiEOG091G01XS
TreeFamiTF350216

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 5 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequencei

Sequence statusi: Complete.

F1M2B7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METSAQAPAL EKKEAKSGLL EDSSFPDPGK KACPLAVAAP AAAVAAQGVP
60 70 80 90 100
QQLLPSFHVP LPIDMRHQEG RYHYDPHPVH GVHGPPTLSG SPVISDISLI
110 120 130 140 150
RLSPHPAGPG ESPFSAHHPY MNPHMEHYLR SVHSSPTLSM ISAARGLSPA
160 170 180 190 200
DVAHEHLKER GLFSLAAPGT NPSDYYHQMT LMASHPTPYG DILMQSGGAA
210 220 230 240 250
SAPHLHDYLN PVDASRFSSP RVTPRLSRKR ALSISPLSDA SLDLQRMIRT
260 270 280 290 300
SPNSLVAYIN NSRSSSAASG SYGHLSAGAL SPAFTFPHPI NPVAYQQILS
310 320 330 340 350
QQRGLGSAFG HTPPLIQPSP TFLAQQPMTL TSITVPTQLG SNSSNCISDA
360 370 380 390 400
NQNKQNSESA VSSTVNPITI HKRSKVKTEA EGLRPASPLG LTQEQLADLK
410 420 430 440 450
EDLDRDDCKQ EAEVVIYETN CHWADCTKEY DTQEQLVHHI NNEHIHGEKK
460 470 480 490 500
EFVCRWQACT REQKPFKAQY MLVVHMRRHT GEKPHKCTFE GCSKAYSRLE
510 520 530 540 550
NLKTHLRSHT GEKPYVCEHE GCNKAFSNAS DRAKHQNRTH SNEKPYICKI
560 570 580 590 600
PGCTKRYTDP SSLRKHVKTV HGPDAHVTKK QRNDVHLRAP LLKENGDNEA
610 620 630 640 650
GAEPGGRGPE ESVEASSTSH TAEDCLHIKA IKTESSGLCQ SSPGAQSSCS
660 670 680 690 700
SEPSPLGSVP NNDSGVEMPG TGPGSLGDLT ALDDTSPGAD TSALAVPSTG
710 720 730 740 750
GLQLRKHMTT MHRFEQLKRE KLKSLKDSCS WAGPAPHTRN TKLPPLPVNG
760 770 780 790 800
SVLENFNNTG GCGPAGLLPN QRLPELTEVT MLSQLQERRD SSTSTMSSAY
810 820 830 840 850
TVSRRSSGIS PYFSSRRSSE ASPLGGIRPH NASSADSYDP ISTDASRRSS
860 870 880 890 900
EASQCSGGGP GLLNLTPAQQ YSLRAKYAAA TGGPPPTPLP GLDRVSLRTR
910 920 930 940 950
LALLDAPERA LPGACPQPLG PRRGSDGPTY NHGHGYVGAA PALPHEGPNG
960 970 980 990 1000
STRRASDPVR RPDPLVLPRV QRFHSIHNMN PGPLPPCTDR RGLHLQSHPS
1010 1020 1030 1040 1050
VDGSLTRHAY SPRPPSINEN VVMEAVAAGV EGAGLESDLG LVEDDLVLPD
1060 1070 1080 1090 1100
DVVQYIKAHT GGALDDSTRQ VYPTEGTGFP ENSKLPSPGL QGHRRLAAAD
1110 1120 1130 1140 1150
SNMSPSAPGL GGCQLSYSPS SSLNKSNMPV QWNEVSSGTV DALPTQVKPP
1160 1170 1180 1190 1200
SFPQSNLVQQ KPAFAHYPGY SPQALQSGSG GLDSTQPHLQ LRGAPSASRG
1210 1220 1230 1240 1250
SYTQQPRLPA TGSQCLGVTA AMSPQANYSQ THHQLSPNVV SGSLNQFAPS
1260 1270 1280 1290 1300
CSNMAAKPSH LGLPQQMEVV PNATIISGHQ RELGIASSSL AAVSQPHPVL
1310 1320 1330 1340 1350
GYPQQDGYQQ VSGLPSSHQP SFMESQQNTG FGLMQPRPPL EPNTASRHRG
1360 1370 1380 1390 1400
VRSGQQQQQL YARTAGQAVV TSANQETAEA MPKGTAGTVV SLTPQPSQDT
1410 1420 1430 1440 1450
GRSQDQNTLY YYGQIHMYEQ NGGCPAMQPQ PPQPQGCSDN IQPEPLPSPG
1460 1470 1480 1490 1500
VNQVSSTVDS QLLEPPQIDF DAIMDDGDHS SLFSGALSPS LLHNLSQNSS
1510 1520 1530 1540
RLTTPRNSLT LPSIPVGISN MAVGDMSSML TSLAEENKFL NMMT
Length:1,544
Mass (Da):165,094
Last modified:July 22, 2015 - v3
Checksum:iEBAC817D74AD0FCA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07020674 Genomic DNA No translation available.
AABR07020675 Genomic DNA No translation available.
AABR07020676 Genomic DNA No translation available.
AABR07020677 Genomic DNA No translation available.
RefSeqiXP_008767677.1, XM_008769455.2
XP_017454273.1, XM_017598784.1
UniGeneiRn.38778

Genome annotation databases

EnsembliENSRNOT00000009963; ENSRNOP00000009963; ENSRNOG00000007261
GeneIDi304729

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07020674 Genomic DNA No translation available.
AABR07020675 Genomic DNA No translation available.
AABR07020676 Genomic DNA No translation available.
AABR07020677 Genomic DNA No translation available.
RefSeqiXP_008767677.1, XM_008769455.2
XP_017454273.1, XM_017598784.1
UniGeneiRn.38778

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000009963

Proteomic databases

PaxDbiF1M2B7
PRIDEiF1M2B7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000009963; ENSRNOP00000009963; ENSRNOG00000007261
GeneIDi304729

Organism-specific databases

CTDi2736
RGDi1309270 Gli2

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00900000140802
OMAiVVQYIKS
OrthoDBiEOG091G01XS
TreeFamiTF350216

Enzyme and pathway databases

ReactomeiR-RNO-5610787 Hedgehog 'off' state
R-RNO-5632684 Hedgehog 'on' state

Gene expression databases

BgeeiENSRNOG00000007261 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 5 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 5 hits
SUPFAMiSSF57667 SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 4 hits
PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiF1M2B7_RAT
AccessioniPrimary (citable) accession number: F1M2B7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 22, 2015
Last modified: November 7, 2018
This is version 67 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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