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UniProtKB - F1M1B3 (F1M1B3_RAT)

Entry version 65 (02 Dec 2020)
Sequence version 2 (03 Apr 2013)
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Protein

WASH complex subunit 5

Gene

Washc5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WASH complex subunit 5ARBA annotation
Alternative name(s):
WASH complex subunit strumpellinARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Washc5Imported
Synonyms:RGD1564420Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Rat genome database

More...RGDi		1564420, Washc5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		F1M1B3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F1M1B3

PeptideAtlas

More...PeptideAtlasi		F1M1B3

PRoteomics IDEntifications database

More...PRIDEi		F1M1B3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSRNOG00000009739, Expressed in adult mammalian kidney and 20 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		F1M1B3, 1 interactor

STRING: functional protein association networks

More...STRINGi		10116.ENSRNOP00000013315

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the strumpellin family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3666, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011137

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_004021_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F1M1B3

Identification of Orthologs from Complete Genome Data

More...OMAi		HTQVQQF

Database of Orthologous Groups

More...OrthoDBi		88928at2759

TreeFam database of animal gene trees

More...TreeFami		TF314480

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR019393, WASH_strumpellin

The PANTHER Classification System

More...PANTHERi		PTHR15691, PTHR15691, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10266, Strumpellin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1M1B3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLDFLAENNL CGQAILRIVS CGNAIIAEVL RLSEFIPAVF LLKDRADQQR 
        60         70         80         90        100
YGDIIFDFSY FKGPEFWESK LEARPELQDL DEEFRENNIE IVTRFYLAFQ 
       110        120        130        140        150
SVHKYIVDLN RYLDDLNEGV YIQQTLETVL LNEDGKQLLC EALYLYGVML 
       160        170        180        190        200
LVIDQKIEGE VRERMLVSYY RYSAARSSAD SNLDDICKLL RSTGYSSQPG 
       210        220        230        240        250
AKRPPSYPES YFQRVPINPT FISMAIGRLR SDDIYNQVSA YPLPEHRSTA 
       260        270        280        290        300
LANQAAMLYV ILYFEPSILH THQAKMREIV DKYFPDNWVI SIYMGITVNL 
       310        320        330        340        350
ADAWEPYKAA KTALNNTLDL PNVKEQASRY ASVSERVRAQ VQQFLKEGYL 
       360        370        380        390        400
REEVLLDNIP RLLNCLRDCN VAIRWLMLHT ADSACDPNNK RLRQIKDQIL 
       410        420        430        440        450
ADSRYNPKIL FQLLLDTAQF EFILKEMFKQ MLSEKQSKWE HYKKEGSERM 
       460        470        480        490        500
IELADVFSGV KPLTRVEKNE NLQAWFREIS KQILSLNYDD STAAGRKTVQ 
       510        520        530        540        550
LIQALEEVQE FHQLESNLQV CQFLADTRKF LHQMIRTINI KEEVLITMQI 
       560        570        580        590        600
VGDLSFAWQL IDSFTSIMQE SIRVNPSMVT KLRATFLKLA SALDLPLLRI 
       610        620        630        640        650
NQANSPDLLS VSQYYSGELV SYVRKVLQII PESMFTSLLK IIKLQTHDII 
       660        670        680        690        700
EVPTRLDKDK LRDYAQLGPR YEVAKLTHAI SIFTEGILMM KTTLVGIIKV 
       710        720        730        740        750
DPKQLLEDGI RKELVKRVAF ALHRGLIFNP RAKPSELMPK LKELGATMDG 
       760        770        780        790        800
FHRSFEYIQD YVNIYGLKIW QEEVSRIINY NVEQECNNFL RTKIQDWQSI 
       810        820        830        840        850
YQSTHIPIPK FAPVDESITF IGRLCREILR ITDPKVTCYI DQLNTWYDMK 
       860        870        880        890        900
TRQEVTSSRL FSEIQTTLGT FGLNGLDRLL CFMIVKELQN FLSMFQKIIL 
       910        920        930        940        950
RERTVQETLK TLMNAVSPLR SIVANSSKVY LAAITKTQKI WSTYLEAIMK 
       960        970        980        990       1000
VGQMQILRRQ IANELNSSCR FDSRHLAAAL DNLNKALLAD IEAHYRDPSL 
      1010       1020       1030       1040       1050
PYPKEDNTLL YEITAYLEAA GIHNPLNKIY ITTKRLPYFP IVNFLFLIAQ 
      1060       1070       1080       1090       1100
LPKLQYNKNL GMVCRKPADP VDWPPLVLGL LTLLKQFHSR YTEQFLALIG 
      1110       1120       1130       1140       1150
QFIRSTMEQC TSQKMPEMPA DAVGALLFLE DYVRYTKLPR RVAEAHVPNF 

IFDEFRTVL
Length:1,159
Mass (Da):134,209
Last modified:April 3, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB7B62BB844B8C0F3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AABR07058085 Genomic DNA No translation available.
AABR07058086 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		XP_002729862.2, XM_002729816.5
XP_006226143.1, XM_006226081.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSRNOT00000013315; ENSRNOP00000013315; ENSRNOG00000009739

Database of genes from NCBI RefSeq genomes

More...GeneIDi		362919

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		rno:362919

UCSC genome browser

More...UCSCi		RGD:1564420, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058085 Genomic DNA No translation available.
AABR07058086 Genomic DNA No translation available.
RefSeqiXP_002729862.2, XM_002729816.5
XP_006226143.1, XM_006226081.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

IntActiF1M1B3, 1 interactor
STRINGi10116.ENSRNOP00000013315

Proteomic databases

jPOSTiF1M1B3
PaxDbiF1M1B3
PeptideAtlasiF1M1B3
PRIDEiF1M1B3

Genome annotation databases

EnsembliENSRNOT00000013315; ENSRNOP00000013315; ENSRNOG00000009739
GeneIDi362919
KEGGirno:362919
UCSCiRGD:1564420, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9897
RGDi1564420, Washc5

Phylogenomic databases

eggNOGiKOG3666, Eukaryota
GeneTreeiENSGT00390000011137
HOGENOMiCLU_004021_1_0_1
InParanoidiF1M1B3
OMAiHTQVQQF
OrthoDBi88928at2759
TreeFamiTF314480

Gene expression databases

BgeeiENSRNOG00000009739, Expressed in adult mammalian kidney and 20 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR019393, WASH_strumpellin
PANTHERiPTHR15691, PTHR15691, 1 hit
PfamiView protein in Pfam
PF10266, Strumpellin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1M1B3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1M1B3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: December 2, 2020
This is version 65 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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