Ascl5

Functionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro
RNA polymerase II regulatory region sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
transcription factor binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

positive regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Achaete-scute family bHLH transcription factor 5Imported Submitted name: RCG45930Imported
Gene namesⁱ	Name:Ascl5Imported ORF Names:rCG_45930Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 13

Organism-specific databases

Rat genome database More...RGDⁱ	1561854 Ascl5

RGDⁱ

1561854 Ascl5

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	F1LUI6

PRIDEⁱ

F1LUI6

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000033391 Expressed in 1 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000033391 Expressed in 1 organ(s), highest expression level in brain

Interactionⁱ

GO - Molecular functionⁱ

protein dimerization activity Source: InterPro
transcription factor binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000048485

STRINGⁱ

10116.ENSRNOP00000048485

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	80 – 132	BHLHInterPro annotationAdd BLAST		53

Phylogenomic databases

eggNOGⁱ	KOG4029 Eukaryota ENOG411227D LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063321
KEGG Orthology (KO) More...KOⁱ	K09067
OMAⁱ	VPFPGAF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0RR2
TreeFamⁱ	TF322889

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR015660 MASH1/Ascl1a-like
PANTHERⁱ	PTHR13935 PTHR13935, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

F1LUI6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNSNFCRALV DRGSPGGIQL GVVAPAGPTP LAATEPLGNV PFLLYPGHSE 
        60         70         80         90        100
PSYYDAYTGV FPYVPFPGAF GVYDYPFEPA FIQKRNERER QRVKCVNEGY 
       110        120        130        140        150
ARLRGHLPGA LAEKRLSKVE TLRAAIRYIK YLQELLSAAP DGAPPTATSP 
       160        170        180 
PPAHAGHGNA LQPPSLVAES SGSSFSPSPF LESEEPSL

Length:188

Mass (Da):20,154

Last modified:April 3, 2013 - v2

Checksum:ⁱ19E07C8E1DE320CA

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07021000 Genomic DNA No translation available. CH473958 Genomic DNA Translation: EDM09670.1
NCBI Reference Sequences More...RefSeqⁱ	XP_017454536.1, XM_017599047.1 XP_017460187.1, XM_017604698.1

Genome annotation databases

Ensemblⁱ	ENSRNOT00000048033; ENSRNOP00000048485; ENSRNOG00000033391
GeneIDⁱ	363991
KEGGⁱ	rno:363991

Protein	Similar proteins		Species	Score	Length	Source
F1LUI6	Achaete-scute family bHLH transcription factor 5		MOUSE		188	UniRef90_M0QWB7
UPI000A318A68		MUSCR		188
UPI000A30518D		MUSPA		187

Protein	Similar proteins		Species	Score	Length	Source
F1LUI6	Achaete-scute family bHLH transcription factor 5		MOUSE		188	UniRef50_M0QWB7
achaete-scute homolog 5		MESAU		189
Uncharacterized protein		MACMU		206
Uncharacterized protein		CERAT		206
Achaete-scute family bHLH transcription factor 5		CALJA		206
+75

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07021000 Genomic DNA No translation available. CH473958 Genomic DNA Translation: EDM09670.1
RefSeqⁱ	XP_017454536.1, XM_017599047.1 XP_017460187.1, XM_017604698.1

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000048485

STRINGⁱ

10116.ENSRNOP00000048485

Proteomic databases

PRIDEⁱ	F1LUI6

PRIDEⁱ

F1LUI6

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000048033; ENSRNOP00000048485; ENSRNOG00000033391
GeneIDⁱ	363991
KEGGⁱ	rno:363991

Organism-specific databases

CTDⁱ	647219
RGDⁱ	1561854 Ascl5

Phylogenomic databases

eggNOGⁱ	KOG4029 Eukaryota ENOG411227D LUCA
GeneTreeⁱ	ENSGT00530000063321
KOⁱ	K09067
OMAⁱ	VPFPGAF
OrthoDBⁱ	EOG091G0RR2
TreeFamⁱ	TF322889

Gene expression databases

Bgeeⁱ	ENSRNOG00000033391 Expressed in 1 organ(s), highest expression level in brain

Bgeeⁱ

ENSRNOG00000033391 Expressed in 1 organ(s), highest expression level in brain

Family and domain databases

CDDⁱ	cd00083 HLH, 1 hit
Gene3Dⁱ	4.10.280.10, 1 hit
InterProⁱ	View protein in InterPro IPR011598 bHLH_dom IPR036638 HLH_DNA-bd_sf IPR015660 MASH1/Ascl1a-like
PANTHERⁱ	PTHR13935 PTHR13935, 1 hit
Pfamⁱ	View protein in Pfam PF00010 HLH, 1 hit
SMARTⁱ	View protein in SMART SM00353 HLH, 1 hit
SUPFAMⁱ	SSF47459 SSF47459, 1 hit
PROSITEⁱ	View protein in PROSITE PS50888 BHLH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F1LUI6_RAT
Accessionⁱ	F1LUI6Primary (citable) accession number: F1LUI6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 3, 2011
	Last sequence update:	April 3, 2013
	Last modified:	November 7, 2018
	This is version 55 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F1LUI6 (F1LUI6_RAT)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Achaete-scute family bHLH transcription factor 5

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ