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UniProtKB - F1LUI6 (F1LUI6_RAT)
Protein
Submitted name:
Achaete-scute family bHLH transcription factor 5
Gene
Ascl5
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein dimerization activity Source: InterPro
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- positive regulation of transcription by RNA polymerase II Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Achaete-scute family bHLH transcription factor 5Submitted name: RCG45930Imported |
Gene namesi | Name:Ascl5Imported ORF Names:rCG_45930Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1561854, Ascl5 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000033391, Expressed in liver and 3 other tissues |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000048485 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 80 – 132 | BHLHInterPro annotationAdd BLAST | 53 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 141 – 188 | DisorderedSequence analysisAdd BLAST | 48 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 164 – 188 | Polar residuesSequence analysisAdd BLAST | 25 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00940000163864 |
HOGENOMi | CLU_095919_0_0_1 |
OMAi | CMQLGVV |
OrthoDBi | 1545499at2759 |
TreeFami | TF322889 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR015660, MASH1/Ascl1a-like |
PANTHERi | PTHR13935, PTHR13935, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
F1LUI6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNSNFCRALV DRGSPGGIQL GVVAPAGPTP LAATEPLGNV PFLLYPGHSE
60 70 80 90 100
PSYYDAYTGV FPYVPFPGAF GVYDYPFEPA FIQKRNERER QRVKCVNEGY
110 120 130 140 150
ARLRGHLPGA LAEKRLSKVE TLRAAIRYIK YLQELLSAAP DGAPPTATSP
160 170 180
PPAHAGHGNA LQPPSLVAES SGSSFSPSPF LESEEPSL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473958 Genomic DNA Translation: EDM09670.1 |
RefSeqi | XP_017454536.1, XM_017599047.1 XP_017460187.1, XM_017604698.1 |
Genome annotation databases
Ensembli | ENSRNOT00000048033.4; ENSRNOP00000048485.3; ENSRNOG00000033391.4 |
GeneIDi | 363991 |
KEGGi | rno:363991 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH473958 Genomic DNA Translation: EDM09670.1 |
RefSeqi | XP_017454536.1, XM_017599047.1 XP_017460187.1, XM_017604698.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000048485 |
Genome annotation databases
Ensembli | ENSRNOT00000048033.4; ENSRNOP00000048485.3; ENSRNOG00000033391.4 |
GeneIDi | 363991 |
KEGGi | rno:363991 |
Organism-specific databases
CTDi | 647219 |
RGDi | 1561854, Ascl5 |
Phylogenomic databases
eggNOGi | KOG4029, Eukaryota |
GeneTreei | ENSGT00940000163864 |
HOGENOMi | CLU_095919_0_0_1 |
OMAi | CMQLGVV |
OrthoDBi | 1545499at2759 |
TreeFami | TF322889 |
Gene expression databases
Bgeei | ENSRNOG00000033391, Expressed in liver and 3 other tissues |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf IPR015660, MASH1/Ascl1a-like |
PANTHERi | PTHR13935, PTHR13935, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F1LUI6_RAT | |
Accessioni | F1LUI6Primary (citable) accession number: F1LUI6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | April 3, 2013 | |
Last modified: | May 25, 2022 | |
This is version 74 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |