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Protein
Submitted name:

Kruppel-like factor 5

Gene

Klf5

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Kruppel-like factor 5Imported
Gene namesi
Name:Klf5Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi621446 Klf5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1LSL7
PRIDEiF1LSL7

Expressioni

Gene expression databases

BgeeiENSRNOG00000008785 Expressed in 9 organ(s), highest expression level in colon
ExpressionAtlasiF1LSL7 baseline and differential
GenevisibleiF1LSL7 RN

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000054653

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini359 – 388C2H2-typeInterPro annotationAdd BLAST30
Domaini389 – 418C2H2-typeInterPro annotationAdd BLAST30
Domaini419 – 443C2H2-typeInterPro annotationAdd BLAST25

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118998
InParanoidiF1LSL7
OMAiMPNQFLQ
OrthoDBiEOG091G1BN0
TreeFamiTF350556

Family and domain databases

InterProiView protein in InterPro
IPR030401 KLF5
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR44295:SF4 PTHR44295:SF4, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F1LSL7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPTRVLTMSA RLGPVPQPPA AQDEPVFAQL KPVLGAANPV RDAALFPGDD
60 70 80 90 100
LKHAHHHPPA PPPAAGPRLP SEELVQTRCE MEKYLTPQLP PVPIISEHKK
110 120 130 140 150
YRRDSASVVD QFFTDTEGLP YSINMNVFLP DITHLRTGLY KSQRPCVTQI
160 170 180 190 200
KTEPVTIFSH QSESTAPPPP APTQALPEFT SIFSSHQTTA PEVNNIFIKQ
210 220 230 240 250
ELPIPDLHLS VPSQQGHLYQ LLNTPDLDMP SSTNQTAVMD TLNVSMAGLN
260 270 280 290 300
SHPSAVPQTS MKQFQGMPPC TYTMPSQFLP QQATYFPPSP PSSEPGSPDR
310 320 330 340 350
QAEMLQNLTP PPSYAATIAS KLAIHNPNLP ATLPVNSPNI QPVRYNRRSN
360 370 380 390 400
PDLEKRRIHF CDYDGCTKVY TKSSHLKAHL RTHTGEKPYK CTWEGCDWRF
410 420 430 440
ARSDELTRHY RKHTGAKPFQ CVVCNRSFSR SDHLALHMKR HQN
Length:443
Mass (Da):49,444
Last modified:April 3, 2013 - v2
Checksum:i6B20B84D9D0434C4
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q66HP1Q66HP1_RAT
Klf5 protein
Klf5
363Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07019015 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000057843; ENSRNOP00000054653; ENSRNOG00000008785

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07019015 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000054653

Proteomic databases

PaxDbiF1LSL7
PRIDEiF1LSL7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000057843; ENSRNOP00000054653; ENSRNOG00000008785

Organism-specific databases

RGDi621446 Klf5

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000118998
InParanoidiF1LSL7
OMAiMPNQFLQ
OrthoDBiEOG091G1BN0
TreeFamiTF350556

Gene expression databases

BgeeiENSRNOG00000008785 Expressed in 9 organ(s), highest expression level in colon
ExpressionAtlasiF1LSL7 baseline and differential
GenevisibleiF1LSL7 RN

Family and domain databases

InterProiView protein in InterPro
IPR030401 KLF5
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PANTHERiPTHR44295:SF4 PTHR44295:SF4, 1 hit
PfamiView protein in Pfam
PF00096 zf-C2H2, 3 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetiSearch...

Entry informationi

Entry nameiF1LSL7_RAT
AccessioniPrimary (citable) accession number: F1LSL7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: November 7, 2018
This is version 64 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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