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Protein
Submitted name:

Origin recognition complex subunit 3

Gene

Orc3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-176187 Activation of ATR in response to replication stress
R-RNO-68616 Assembly of the ORC complex at the origin of replication
R-RNO-68689 CDC6 association with the ORC:origin complex
R-RNO-68827 CDT1 association with the CDC6:ORC:origin complex
R-RNO-68867 Assembly of the pre-replicative complex
R-RNO-68949 Orc1 removal from chromatin
R-RNO-68962 Activation of the pre-replicative complex

Names & Taxonomyi

Protein namesi
Submitted name:
Origin recognition complex subunit 3Imported
Gene namesi
Name:Orc3Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 5

Organism-specific databases

RGDi1308457 Orc3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000008314 Expressed in 9 organ(s), highest expression level in testis
ExpressionAtlasiF1LSH3 baseline and differential

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2538 Eukaryota
ENOG410XT1W LUCA
GeneTreeiENSGT00390000011376
OMAiECGRMIN
OrthoDBiEOG091G0AI5
TreeFamiTF101093

Family and domain databases

InterProiView protein in InterPro
IPR020795 ORC3
PANTHERiPTHR12748 PTHR12748, 1 hit
PfamiView protein in Pfam
PF07034 ORC3_N, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

F1LSH3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATSSVSKGC FVFKPDFKKR KISVPIEDYF NNEELDSEDS KLRFETYRLL
60 70 80 90 100
WQRIKSETEQ LQEGLNENLF DNLVDFLQKS HSELQKNSGN WGSQMRLREI
110 120 130 140 150
PTAALILGVN VTDHDVIFRS LTETLHNNVT PYVVSLQAKD CPDVKHFLQK
160 170 180 190 200
LTSELIDCCV DRNSKEEKND KALRRTSYSM DSLSSWYSTV AQKTGPKMTS
210 220 230 240 250
KKRATCSQWQ SPPVVLILKN MESFSTKVLQ DFIIISSQHL HEFPLILIFG
260 270 280 290 300
IATSPVIIHR LLPHSVSSLL CIELFQSLSC KEHLTVVLDK LLLTPQFPFK
310 320 330 340 350
LSKKALQVLT NIFLYHDFSI QNFIKGLKLS LLEHFYSQPL SVLCCDLSEA
360 370 380 390 400
KKRINVFSVN QCEKIRRLPS FRRYVENQPL EKQVALLTNE TFLKEETQSL
410 420 430 440 450
LEDLHVYHIN YFLVLRCLHN FTSSLPKYPL GRQIRELYCT CLEKKIWDSE
460 470 480 490 500
EYESALQLLR MLAKDELMGI LEQCVKVLNS STEKQLSNTA QKIKGFLTQF
510 520 530 540 550
QNLDDSKEEE DACGSQPKGL QKTDLYHLQK SLLEMKELRR TTKKPTKFEM
560 570 580 590 600
LRENVINFID NLVRDYLLPP EGQPLHEVVY FSAANTLREH LNAAPRIALH
610 620 630 640 650
TALNNPYYYL KNEALKSEEG CIPSVAPDIC IAYKLHLECS RLINLVDWSE
660 670 680 690 700
AFATVVTAAE KMDTNSTVSE EMSEIIHARF IRAVSELELL GFIKPTKQKT
710
DHVARLTWGG C
Length:711
Mass (Da):81,867
Last modified:April 3, 2013 - v2
Checksum:i25DB9E205C0333A7
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q4R180ORC3_RAT
Origin recognition complex subunit ...
Orc3 Orc3l
711Annotation score:
A0A0G2K0G7A0A0G2K0G7_RAT
Origin recognition complex subunit ...
Orc3
617Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07047841 Genomic DNA No translation available.
AABR07047842 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000011085; ENSRNOP00000011085; ENSRNOG00000008314

Similar proteinsi

Entry informationi

Entry nameiF1LSH3_RAT
AccessioniPrimary (citable) accession number: F1LSH3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: April 3, 2013
Last modified: September 12, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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