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Entry version 59 (12 Aug 2020)
Sequence version 1 (03 May 2011)
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Protein

Activating signal cointegrator 1 complex subunit 3

Gene

Ascc3

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi500 – 507ATPPROSITE-ProRule annotation8
Nucleotide bindingi1350 – 1357ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase
Biological processDNA damage, DNA repair, Transcription, Transcription regulation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Activating signal cointegrator 1 complex subunit 3 (EC:3.6.4.12By similarity)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ascc3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
1307995, Ascc3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004169161 – 2197Activating signal cointegrator 1 complex subunit 3Add BLAST2197

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei12PhosphoserineBy similarity1
Modified residuei573N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F1LPQ2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1LPQ2

PRoteomics IDEntifications database

More...
PRIDEi
F1LPQ2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F1LPQ2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
F1LPQ2

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Identified in the ASCC complex that contains ASCC1, ASCC2 and ASCC3. Functions as scaffolding subunit that interacts directly with both ASCC1 and ASCC2.

Interacts directly with ALKBH3, and thereby recruits ALKBH3 to the ASCC complex. Part of the ASC-1/TRIP4 complex, that contains TRIP4, ASCC1, ASCC2 and ASCC3.

Interacts with ZCCHC4 (By similarity).

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000053848

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F1LPQ2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini487 – 670Helicase ATP-binding 1PROSITE-ProRule annotationAdd BLAST184
Domaini697 – 915Helicase C-terminal 1PROSITE-ProRule annotationAdd BLAST219
Domaini979 – 1288SEC63 1Add BLAST310
Domaini1337 – 1512Helicase ATP-binding 2PROSITE-ProRule annotationAdd BLAST176
Domaini1565 – 1739Helicase C-terminal 2PROSITE-ProRule annotationAdd BLAST175
Domaini1812 – 2175SEC63 2Add BLAST364

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili18 – 80Sequence analysisAdd BLAST63
Coiled coili328 – 356Sequence analysisAdd BLAST29

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi612 – 615DEVH box4
Motifi1454 – 1457DEIH box4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the helicase family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0952, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1LPQ2

TreeFam database of animal gene trees

More...
TreeFami
TF105778

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR035892, C2_domain_sf
IPR011545, DEAD/DEAH_box_helicase_dom
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR014756, Ig_E-set
IPR027417, P-loop_NTPase
IPR004179, Sec63-dom
IPR036390, WH_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00270, DEAD, 2 hits
PF00271, Helicase_C, 2 hits
PF02889, Sec63, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits
SM00487, DEXDc, 2 hits
SM00490, HELICc, 2 hits
SM00973, Sec63, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46785, SSF46785, 2 hits
SSF52540, SSF52540, 3 hits
SSF81296, SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 2 hits
PS51194, HELICASE_CTER, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F1LPQ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALPRLTGAL RSFSNVTKQD NYNEEVADLK LKRSKLHEQA LDFGLSWKKI
60 70 80 90 100
VKFLNEKLEK NKMQTINEDL KDILQAAKQI VGTDNGNEAI ESGAAFLFMT
110 120 130 140 150
FHMTDSVGYT ETKAIRQMFG PFPSSSATSA CNATSRIISH FSQDDLTALV
160 170 180 190 200
QATENQCNDR VVFGRNLAFS FDMHDLDHFD ELPVNGEAQK TISLDYKKFL
210 220 230 240 250
NEQFQEPYTP ELKPVEKSNG SLLWCEVEKY LNATLKEMTE APRVEDLCCT
260 270 280 290 300
LYDMLASAKS GDELQDELFE LLGPGGLDLI EKLLQNRITI VDRFLNSSSD
310 320 330 340 350
HKFQVLQDNC KKILGENAKP NYGCQVTIQS EQEKQLMKQY RREEKRIARR
360 370 380 390 400
EKKAGEDGEV SGEGLLPFDP KELRLQREHA LLNARSAPIL GRQRDTEVEK
410 420 430 440 450
IRYPHVYDSQ AAARETSAFI AGAKMILPEG IQRENTKLYE EVRIPYSEPM
460 470 480 490 500
PVGFEEKPVY IQDLDEVGQL AFKGMKRLNR IQSIVFDTAY NTNENMLICA
510 520 530 540 550
PTGAGKTNIA MLTVLHEIRQ HFHQGVLKKN EFKIVYVAPM KALAAEMTNY
560 570 580 590 600
FSKRLEPLGI VVKELTGDMQ LSKSEILRTQ MLVTTPEKWD VVTRKSVGDV
610 620 630 640 650
ALSQIVKLLI LDEVHLLHED RGPVLESIVA RTLRQVESTQ SMIRILGLSA
660 670 680 690 700
TLPNYLDVAT FLHVNPYIGL FYFDGRFRPV PLGQTFLGIK SANKMQQLNN
710 720 730 740 750
MDEVCYESVL KQVKAGHQVM VFVHARNATV RTAMSLIERA KNSGQISCFL
760 770 780 790 800
PTQGPEYGHA LKQVQKSRNK QVRELFSDGF SIHHAGMLRQ DRNLVENLFS
810 820 830 840 850
NGHIKVLVCT ATLAWGVNLP AHAVIIKGTQ IYAAKRGSFV DLGILDVMQI
860 870 880 890 900
FGRAGRPQFD KFGEGIIITT HDKLSHYLSL LTQQNPIESQ FLESLADNLN
910 920 930 940 950
AEIALGTVTN VEEAVKWMSY TYLYVRMRAN PLAYGISHKA YQMDPTLRKH
960 970 980 990 1000
REQLLIEVGQ KLDKARMIRF EERTGYFSST DLGRTASHYY IKYNTIETFN
1010 1020 1030 1040 1050
ELFDAHKTEG DIFAIVSKAE EFDQIKVREE EIEELDALLN NFCELSAPGG
1060 1070 1080 1090 1100
VENSYGKINI LLQTYISRGE MDSFSLISDS AYVAQNAARI VRALFEIALR
1110 1120 1130 1140 1150
KRWPTMTYRL LNLSKVIDKR LWGWASPLRQ FSVLPPHILT RLEEKNLTVD
1160 1170 1180 1190 1200
KLKDMRKDEI GHILHHVNIG LKVKQCVHQI PSVTMEASIQ PITRTVLRVS
1210 1220 1230 1240 1250
LNIYPDFSWN DQVHGTVGEP WWIWVEDPTN DHIYHSEYFL ALKKQVINKE
1260 1270 1280 1290 1300
AQLLVFTIPI FEPLPSQYYI RAVSDRWLGA EAVCIINFQH LILPERHPPH
1310 1320 1330 1340 1350
TELLDLQPLP VTALGCKAYE ALYNFSHFNP VQTQIFHTLY HTDCNVLLGA
1360 1370 1380 1390 1400
PTGSGKTVAA ELAIFRVFNK YPTSKAVYIA PLKALVRERM DDWKIRIEEK
1410 1420 1430 1440 1450
LGKKVIELTG DVTPDMKSIA KADLIVTTPE KWDGVSRSWQ NRSYVQQVNI
1460 1470 1480 1490 1500
LIIDEIHLLG EERGPVLEVI VSRTNFISSH TEKPVRIVGL STALANARDL
1510 1520 1530 1540 1550
ADWLNIKQMG LFNFRPSVRP VPLEVHIQGF PGQHYCPRMA SMNKPAFQES
1560 1570 1580 1590 1600
HTHCPDRPCL LLPERMLSSM TKLELIAFLA TEEDPKQWLN MDEQEMENII
1610 1620 1630 1640 1650
ATVRDSNLKL TLAFGIGMHH AGLHERDRKT VEELFVNCKV QVLIATSTLA
1660 1670 1680 1690 1700
WGVNFPAHLV IIKGTEYYDG KTRRYVDFPI TDVLQMMGRA GRPQFDDQGK
1710 1720 1730 1740 1750
AVILVHDIKK DFYKKFLYEP FPVESSLLGV LSDHLNAEIA GGTITSKQDA
1760 1770 1780 1790 1800
LDYITWTYFF RRLIMNPSYY NLGDVSQDAI NKFLSHLIGQ SLVELELSHC
1810 1820 1830 1840 1850
IEVGEDNRSI EPLTCGRIAS YYYLKHKTVK MFKDRLKPEC STEELLSILS
1860 1870 1880 1890 1900
DAEEYTDLPV RHNEDHTNNE LAKCLPIELN PHSFDSPHTK AHLLLQAHLS
1910 1920 1930 1940 1950
RAMLPCPDYD TDTKTVLDQA LRVCQAMLDV AASQGWLVTT LNITHLIQMV
1960 1970 1980 1990 2000
IQGRWLKDSS LLTIPNIEQH HLHLFRKWKP PVKGPHAKCR TSIECLPELI
2010 2020 2030 2040 2050
HACEGKEHVF SSMVEKELQP AKTKQAWNFL SHLPVINVGI SVKGSWDDSV
2060 2070 2080 2090 2100
EGHNELSIST LTADKRDENT WIKLHADQQY VLQVSLQRVH FEFHKVKHES
2110 2120 2130 2140 2150
HAVTPRFPKL KDEGWFLILG EVDKRELVAV KRVGFVRTHH EASISFFTPE
2160 2170 2180 2190
APGRYIFTLY LMSDCYLGLD QQYDIFLNVT KADISTQINT EVPDVST
Length:2,197
Mass (Da):250,220
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC8A73337406E5F8D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MY43A0A0A0MY43_RAT
Activating signal cointegrator 1 co...
Ascc3
2,201Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

UCSC genome browser

More...
UCSCi
RGD:1307995, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

SMRiF1LPQ2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053848

PTM databases

iPTMnetiF1LPQ2
PhosphoSitePlusiF1LPQ2

Proteomic databases

jPOSTiF1LPQ2
PaxDbiF1LPQ2
PRIDEiF1LPQ2

Genome annotation databases

UCSCiRGD:1307995, rat

Organism-specific databases

RGDi1307995, Ascc3

Phylogenomic databases

eggNOGiKOG0952, Eukaryota
InParanoidiF1LPQ2
TreeFamiTF105778

Miscellaneous databases

Protein Ontology

More...
PROi
PR:F1LPQ2

Family and domain databases

Gene3Di2.60.40.150, 2 hits
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR035892, C2_domain_sf
IPR011545, DEAD/DEAH_box_helicase_dom
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR014756, Ig_E-set
IPR027417, P-loop_NTPase
IPR004179, Sec63-dom
IPR036390, WH_DNA-bd_sf
PfamiView protein in Pfam
PF00270, DEAD, 2 hits
PF00271, Helicase_C, 2 hits
PF02889, Sec63, 2 hits
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SM00487, DEXDc, 2 hits
SM00490, HELICc, 2 hits
SM00973, Sec63, 2 hits
SUPFAMiSSF46785, SSF46785, 2 hits
SSF52540, SSF52540, 3 hits
SSF81296, SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS51192, HELICASE_ATP_BIND_1, 2 hits
PS51194, HELICASE_CTER, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiASCC3_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1LPQ2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: May 3, 2011
Last modified: August 12, 2020
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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