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Entry version 81 (16 Oct 2019)
Sequence version 3 (22 Jul 2015)
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Protein
Submitted name:

Leucine-rich repeat kinase 2

Gene

Lrrk2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-8857538 PTK6 promotes HIF1A stabilization

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Leucine-rich repeat kinase 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Lrrk2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Rat genome database

More...
RGDi
1561168 Lrrk2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1LNJ1

PRoteomics IDEntifications database

More...
PRIDEi
F1LNJ1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F1LNJ1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
F1LNJ1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000004048 Expressed in 9 organ(s), highest expression level in lung

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
F1LNJ1, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000005438

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1327 – 1510RocInterPro annotationAdd BLAST184
Domaini1878 – 2145Protein kinaseInterPro annotationAdd BLAST268

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni956 – 978DisorderedSequence analysisAdd BLAST23

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi957 – 978PolarSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0192 Eukaryota
KOG0619 Eukaryota
COG1100 LUCA
COG4886 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158267

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1LNJ1

Identification of Orthologs from Complete Genome Data

More...
OMAi
CKLIEVC

Database of Orthologous Groups

More...
OrthoDBi
14978at2759

TreeFam database of animal gene trees

More...
TreeFami
TF313679

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 2 hits
1.25.40.20, 1 hit
2.130.10.10, 1 hit
3.80.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036770 Ankyrin_rpt-contain_sf
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032171 COR
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR027417 P-loop_NTPase
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR020859 ROC_dom
IPR008271 Ser/Thr_kinase_AS
IPR005225 Small_GTP-bd_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16095 COR, 1 hit
PF13855 LRR_8, 3 hits
PF00069 Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00369 LRR_TYP, 6 hits
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 3 hits
SSF50978 SSF50978, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00231 small_GTP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450 LRR, 11 hits
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS51424 ROC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1LNJ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASGACQGCD EEEEEEALKK LIVRLNNVQE GKQIETLLQL LEDILVFTYS
60 70 80 90 100
DRASKLFEGK NVHVPLLIVL DSYMRVASVQ QVGWSLLCKL IEVCPGTLQS
110 120 130 140 150
LIGPQDIGND WEVLGIHRLI LKMLTVHHAN VNLSIVGLKA LDLLLDSGKI
160 170 180 190 200
TLLILDEECD VFLLIFDAMH RYSANEEVQK LACKALHVLF ERVSEEQLTE
210 220 230 240 250
FVENKDYMTL LSTFRSFKRD EEIVHHVLCC LHSLAVTCSN VEVLMSGNVR
260 270 280 290 300
CYNIVVEAMK TFPTSENIQE VSCSLLHKLT LGNFFNILVL NEVHVFVVKA
310 320 330 340 350
VQRYPENVAL QISALSCLAL LTETIFLNQD LEERSETQEN SDEDSEKPFW
360 370 380 390 400
LEPCYKALMR HRKNKHVQEA ACWALNNLLM YQSSLHEKIG DEDGQFPAHR
410 420 430 440 450
EVMLSMLMHS SSKDVFQAAA HALSTLLEQN VNFRKILLAK GVYLNVLELM
460 470 480 490 500
QRHAQVPEVA ESGCKMLSHL FEGSNPSLDT VAAVIPKILT VMRTHGTSLS
510 520 530 540 550
VQLEALRALL HFVVPGVSED SRDDSRCQPN VLRTQCFRTD IHKLVLAALN
560 570 580 590 600
RFIGNPGIQK CGLKVISSFA HLPDALEMLS LHGAVDSVLH TLQMYPDDQE
610 620 630 640 650
IQCLGLHLMG CLMTKKNFCI GTGHLLAKIL ASTLQRFKDV AEVQTTGLQT
660 670 680 690 700
VLSMLDLSVS FSKLLVHYSF DVVMFHQMSS GVLEQKDEQF LNLCCKCFAK
710 720 730 740 750
VAVDDELKSK MLERACDQNN SIMVECLLLL GADANQAKGA TSLIYQVCEK
760 770 780 790 800
ESSPKLVELL LNSGCREQDV RKALTVSIQK GDNQVISLLL RRLALDLANN
810 820 830 840 850
SICLGGFCIG KLDPSWLGPL FPDKSSNLRK QTNAGSVLAR KVLRYQMRNT
860 870 880 890 900
LQEGVASGSE GNFSEDALAK FGEWTFIPDS SMDSVFGQSD DLDSEGSESS
910 920 930 940 950
FLVKKKSNSV SVGEVYRDLA LQRCSPNAQR HSSSLGPVFD HEDLLRRKRK
960 970 980 990 1000
ILSSDESLRS SRLQSHTRQS DSSSSLASER EHITSLDLSA NELKDIDALG
1010 1020 1030 1040 1050
QKCCLSSHLE HLTKLELHQN SLTSFPQQLC ETLKCLTHLD LHSNKFATFP
1060 1070 1080 1090 1100
SFMLKMPSVI HLDASRNDIG PTVVLDPVVK CPSLKQFNLS YNQLSSIPEN
1110 1120 1130 1140 1150
LDQVVEKLEQ LLLEGNKISG ICSPLSLKEL KILNLSKNHI PSLPEDFLEA
1160 1170 1180 1190 1200
CPKVESFSAR MNFLAAMPAL PSSITSLKLS QNSFTCIPEA IFSLPHLRSL
1210 1220 1230 1240 1250
DMSHNNIEHL PGPAHWKSLN LRELIFSKNQ ISTLDLSENP HIWSRVEKLH
1260 1270 1280 1290 1300
LSHNKLKEIP PEIGRLENLT SLDVSYNLEL RSFPNEMGKL SKIWDLPLDG
1310 1320 1330 1340 1350
LHLNFDFKHI GCKAKDIIRF LQQRLKKAVP YNRMKLMIVG NTGSGKTTLL
1360 1370 1380 1390 1400
QQLMKMKKSE LGMQGATVGI DVRDWPIQIR GKRKKDLVLN VWDFAGREEF
1410 1420 1430 1440 1450
YSTHPHFMTQ RALYLAVYDL SKGQAEVDAM KPWLFNIKAR ASSSPVILVG
1460 1470 1480 1490 1500
THLDVSDEKQ RKACIGKITK ELLNKRGFPT IRDYHFVNAT EESDALAKLR
1510 1520 1530 1540 1550
KTIINESLNF KIRDQPVVGQ LIPDCYVELE KIILSERKAV PTEFPVINRK
1560 1570 1580 1590 1600
HLLQLVKEHQ LQLDENELPH AVHFLNESGV LLHFQDPALQ LSDLYFVEPK
1610 1620 1630 1640 1650
WLCKVMAQIL TVKVDGCLKH PKGIISRRDV EKFLSKKKRF PKNYMAQYFK
1660 1670 1680 1690 1700
LLEKFQIALP IGEEYLLVPS SLSDHRPVIE LPHCENSEII IRLYEMPYFP
1710 1720 1730 1740 1750
MGFWSRLINR LLEISPFMLS GRERALRPNR MYWRQGIYLN WSPEAYCLVG
1760 1770 1780 1790 1800
SEVLDSRPES FLKITVPSCR KGCILLGRVV DHIDSLMEEW FPGLLEIDIC
1810 1820 1830 1840 1850
GEGETLLKKW ALYSFNDGEE HQKILLDELM KKAEEGDLLI NPDQPRLTIP
1860 1870 1880 1890 1900
ISQIAPDLIL ADLPRNIMLN NDELEFEEAP EFLLGDGSFG SVYRAAYEGE
1910 1920 1930 1940 1950
EVAVKIFNKH TSLRLLRQEL VVLCHLHHPS LISLLAAGIR PRMLVMELAS
1960 1970 1980 1990 2000
KGSLDRLLQQ DKASLTRTLQ HRIALHVADG LRYLHSAMII YRDLKPHNVL
2010 2020 2030 2040 2050
LFTLYPNAAI IAKIADYGIA QYCCRMGIKT SEGTPGFRAP EVARGNVIYN
2060 2070 2080 2090 2100
QQADVYSFGL LLHDIWTTGN RIMEGLRFPN EFDELAIQGK LPDPVKEYGC
2110 2120 2130 2140 2150
APWPMVEKLI TKCLKENPQE RPTSAQVFDI LNSAELICLM RHIFIPKDIT
2160 2170 2180 2190 2200
VECIAATNLN SKRATLWLGC GNTEKGQLSL LDLNTERYSY EEVTDSRILC
2210 2220 2230 2240 2250
LALVHLAAEK ESWVVCGTQS GALLVINAED ETRRHTLDKM TDSVTCLYCN
2260 2270 2280 2290 2300
SFAKQSKQSH FLLVGTADGN LMIFEDKTIK CKGAAPLKTL HIGDVSTPLM
2310 2320 2330 2340 2350
CLSESMNSSE RHITWGGCGT KIFSFSNDFT IQKLIETRTN QLFSYSAFSD
2360 2370 2380 2390 2400
SNIIAVAVDT ALYIAKKNSP VVEVWDKKTE KLCELIDCVH FLKEVMVKIN
2410 2420 2430 2440 2450
KDSKHKLSYS GRVKALCLQK NTALWIGTGG GHILLLDLST RRVIRTIHNF
2460 2470 2480 2490 2500
CDSVRAMATA QLGSLKNVML VLGYKRKSTE GTQEQKEIQS CLSIWDLNLP
2510 2520
HEVQNLEKHI EVRTELADKM RKTSVE
Length:2,526
Mass (Da):284,831
Last modified:July 22, 2015 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDB5CA86E1E96E716
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC108595 Genomic DNA No translation available.
AC112081 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_006242252.1, XM_006242190.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000005438; ENSRNOP00000005438; ENSRNOG00000004048

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
300160

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC108595 Genomic DNA No translation available.
AC112081 Genomic DNA No translation available.
RefSeqiXP_006242252.1, XM_006242190.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiF1LNJ1, 2 interactors
STRINGi10116.ENSRNOP00000005438

PTM databases

iPTMnetiF1LNJ1
PhosphoSitePlusiF1LNJ1

Proteomic databases

PaxDbiF1LNJ1
PRIDEiF1LNJ1

Genome annotation databases

EnsembliENSRNOT00000005438; ENSRNOP00000005438; ENSRNOG00000004048
GeneIDi300160

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
120892
RGDi1561168 Lrrk2

Phylogenomic databases

eggNOGiKOG0192 Eukaryota
KOG0619 Eukaryota
COG1100 LUCA
COG4886 LUCA
GeneTreeiENSGT00940000158267
InParanoidiF1LNJ1
OMAiCKLIEVC
OrthoDBi14978at2759
TreeFamiTF313679

Enzyme and pathway databases

ReactomeiR-RNO-8857538 PTK6 promotes HIF1A stabilization

Gene expression databases

BgeeiENSRNOG00000004048 Expressed in 9 organ(s), highest expression level in lung

Family and domain databases

Gene3Di1.25.10.10, 2 hits
1.25.40.20, 1 hit
2.130.10.10, 1 hit
3.80.10.10, 2 hits
InterProiView protein in InterPro
IPR036770 Ankyrin_rpt-contain_sf
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR032171 COR
IPR011009 Kinase-like_dom_sf
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR027417 P-loop_NTPase
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR020859 ROC_dom
IPR008271 Ser/Thr_kinase_AS
IPR005225 Small_GTP-bd_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF16095 COR, 1 hit
PF13855 LRR_8, 3 hits
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 6 hits
SM00220 S_TKc, 1 hit
SUPFAMiSSF48371 SSF48371, 3 hits
SSF50978 SSF50978, 1 hit
SSF52540 SSF52540, 1 hit
SSF56112 SSF56112, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 11 hits
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS51424 ROC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1LNJ1_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1LNJ1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: July 22, 2015
Last modified: October 16, 2019
This is version 81 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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