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Protein
Submitted name:

CD19 molecule

Gene

Cd19

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-1257604 PIP3 activates AKT signaling
R-RNO-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
R-RNO-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-RNO-977606 Regulation of Complement cascade
R-RNO-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

Names & Taxonomyi

Protein namesi
Submitted name:
CD19 moleculeImported
Gene namesi
Name:Cd19Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi1309086 Cd19

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei288 – 311HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500326876819 – 547Sequence analysisAdd BLAST529

Proteomic databases

PaxDbiF1LNH2
PRIDEiF1LNH2

PTM databases

iPTMnetiF1LNH2
PhosphoSitePlusiF1LNH2

Expressioni

Gene expression databases

BgeeiENSRNOG00000018311

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000051906

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 98Ig-likeInterPro annotationAdd BLAST79
Domaini171 – 259Ig-likeInterPro annotationAdd BLAST89

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ3V Eukaryota
ENOG41115SQ LUCA
GeneTreeiENSGT00390000014991
InParanoidiF1LNH2
KOiK06465
OMAiLYVWAKD
OrthoDBiEOG091G08D8
TreeFamiTF338293

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
SMARTiView protein in SMART
SM00409 IG, 2 hits
SUPFAMiSSF48726 SSF48726, 2 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 2 hits

Sequencei

Sequence statusi: Complete.

F1LNH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPLPVSLL LFLTLVGGRP QNSLLVEVEE GDNVVLSCLR DSSPVSSEKL
60 70 80 90 100
AWYRGNQSTP FLELSLRSPD LGLHIGPLGI LLVIVNVSDH RGGFYLCQKR
110 120 130 140 150
PSFKDTWQPA WTVNVEDSGE LFRWNASDLG DLDCDLGNRS SGSHRSTSGS
160 170 180 190 200
QLYVWATDHP EVWKTKPVCA PREISLNQSL INQDLTVAPG STLWLSCGVP
210 220 230 240 250
PVPVTKGSIS WTHVHPKTLN VSLLSLSLGG EHPVREMWVW GSLLLLPQAK
260 270 280 290 300
ASDEGTYYCL QGGLTIKMHV KVIARSAVWL WLLRTGGWIV PVVTLVYVIF
310 320 330 340 350
CMVSMAAFLY FRRAFILRRK RKRMTDPARR FFKVTPPSGN GTQNQYGNVL
360 370 380 390 400
SLPTSTSGQA HAQRWAASLG SGPVSYGNPR IEVQDAGAQR HETGLEEEGE
410 420 430 440 450
AYEEPDSEEG SEFYENDSNL EQDQLSQDGS GYENPEDDPV GPEEEDSFSN
460 470 480 490 500
AESYENADEE LAQPVGRTMD FLSPHGSAWD PSREASSLGS QSYEDMRGIL
510 520 530 540
YAAPQLQSIR SGPSHEEDAD SYENMDKSDD PEPAWAGEGH MGTWGAT
Length:547
Mass (Da):60,259
Last modified:May 3, 2011 - v1
Checksum:i6DC8AE88558D7817
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07071986 Genomic DNA No translation available.
RefSeqiNP_001013255.2, NM_001013237.3
UniGeneiRn.105569

Genome annotation databases

EnsembliENSRNOT00000055027; ENSRNOP00000051906; ENSRNOG00000018311
GeneIDi365367
KEGGirno:365367

Similar proteinsi

Entry informationi

Entry nameiF1LNH2_RAT
AccessioniPrimary (citable) accession number: F1LNH2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 20, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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