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UniProtKB - F1LN88 (F1LN88_RAT)
Protein
Submitted name:
Aldehyde dehydrogenase, mitochondrial
Gene
Aldh2
Organism
Rattus norvegicus (Rat)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 287 | PROSITE-ProRule annotation | 1 | |
Active sitei | 321 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Source: InterPro
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Aldehyde dehydrogenase, mitochondrialImportedSubmitted name: RCG21519, isoform CRA_aImported |
Gene namesi | Name:Aldh2Imported ORF Names:rCG_21519Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 69219, Aldh2 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000001344, Expressed in liver and 21 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 47 – 510 | AldedhInterPro annotationAdd BLAST | 464 |
Sequence similaritiesi
Belongs to the aldehyde dehydrogenase family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000156240 |
HOGENOMi | CLU_005391_0_1_1 |
OMAi | HGIGYYP |
TreeFami | TF300455 |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F1LN88-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRAALSTAR RGPRLSRLLS AAATSAVPAP NQQPEVFCNQ IFINNEWHDA
60 70 80 90 100
VSKKTFPTVN PSTGEVICQV AEGNKEDVDK AVKAARAAFQ LGSPWRRMDA
110 120 130 140 150
SDRGRLLYRL ADLIERDRTY LAALETLDNG KPYVISYLVD LDMVLKCLRY
160 170 180 190 200
YAGWADKYHG KTIPIDGDFF SYTRHEPVGV CGQIIPWNFP LLMQAWKLGP
210 220 230 240 250
ALATGNVVVM KVAEQTPLTA LYVANLIKEA GFPPGVVNIV PGFGPTAGAA
260 270 280 290 300
IASHEDVDKV AFTGSTEVGH LIQVAAGSSN LKRVTLELGG KSPNIIMSDA
310 320 330 340 350
DMDWAVEQAH FALFFNQGQC CCAGSRTFVQ EDVYDEFVER SVARAKSRVV
360 370 380 390 400
GNPFDSRTEQ GPQVDETQFK KILGYIKSGQ QEGAKLLCGG GAAADRGYFI
410 420 430 440 450
QPTVFGDVKD GMTIAKEEIF GPVMQILKFK TIEEVVGRAN NSKYGLAAAV
460 470 480 490 500
FTKDLDKANY LSQALQAGTV WINCYDVFGA QSPFGGYKMS GSGRELGEYG
510
LQAYTEVKTV TVKVPQKNS
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP11884 | ALDH2_RAT | Aldehyde dehydrogenase, mitochondri... | Aldh2 | 519 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07036373 Genomic DNA No translation available. AABR07036374 Genomic DNA No translation available. CH473973 Genomic DNA Translation: EDM13724.1 CH473973 Genomic DNA Translation: EDM13725.1 CH473973 Genomic DNA Translation: EDM13726.1 |
RefSeqi | XP_006249447.1, XM_006249385.3 |
Genome annotation databases
Ensembli | ENSRNOT00000001816; ENSRNOP00000001816; ENSRNOG00000001344 |
GeneIDi | 29539 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07036373 Genomic DNA No translation available. AABR07036374 Genomic DNA No translation available. CH473973 Genomic DNA Translation: EDM13724.1 CH473973 Genomic DNA Translation: EDM13725.1 CH473973 Genomic DNA Translation: EDM13726.1 |
RefSeqi | XP_006249447.1, XM_006249385.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSRNOT00000001816; ENSRNOP00000001816; ENSRNOG00000001344 |
GeneIDi | 29539 |
Organism-specific databases
CTDi | 217 |
RGDi | 69219, Aldh2 |
Phylogenomic databases
GeneTreei | ENSGT00940000156240 |
HOGENOMi | CLU_005391_0_1_1 |
OMAi | HGIGYYP |
TreeFami | TF300455 |
Gene expression databases
Bgeei | ENSRNOG00000001344, Expressed in liver and 21 other tissues |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F1LN88_RAT | |
Accessioni | F1LN88Primary (citable) accession number: F1LN88 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | April 3, 2013 | |
Last modified: | January 19, 2022 | |
This is version 82 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |