Zfp276

Functionⁱ

GO - Molecular functionⁱ

DNA-binding transcription factor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
transcription regulatory region DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
positive regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Zinc finger protein (C2H2 type) 276Imported
Gene namesⁱ	Name:Zfp276Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 19

Organism-specific databases

Rat genome database More...RGDⁱ	1307469 Zfp276

RGDⁱ

1307469 Zfp276

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	F1LN08
PRIDEⁱ	F1LN08

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000016631 Expressed in 9 organ(s), highest expression level in liver
Genevisibleⁱ	F1LN08 RN

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000022324

STRINGⁱ

10116.ENSRNOP00000022324

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	462 – 492	C2H2-typeInterPro annotationAdd BLAST	31
Domainⁱ	493 – 520	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	521 – 548	C2H2-typeInterPro annotationAdd BLAST	28
Domainⁱ	551 – 579	C2H2-typeInterPro annotationAdd BLAST	29

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063153
InParanoidⁱ	F1LN08
OMAⁱ	IQAVWGC
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G04WK
TreeFamⁱ	TF332664

Family and domain databases

InterProⁱ	View protein in InterPro IPR012934 Znf_AD IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07776 zf-AD, 1 hit PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

F1LN08-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKRDRLGRFL SPGIARQRGS SGSSCGSGRT RGRPSRTGGS SADGAAPQLS 
        60         70         80         90        100
WGSTRSCGDT GEDGTDEAGA GRTLTMGHCR LCHGKFSSRS LRSISERVPG 
       110        120        130        140        150
ETSERLSPGE RVFIRDFQRL LGVAVHQDPA LPQFVCKNCY TQFYQCHSLL 
       160        170        180        190        200
RSFLQRVNVS PAGQRKPCTK VGVQPPTVAE EGACMADLIT SSPQCLHGLV 
       210        220        230        240        250
GWVHEHAVNC GCLPSLQRTL SSEYCGVIQA VWGCDQGHDF TMDTDSGCRA 
       260        270        280        290        300
LLLDSALAVK WGKELAPRLA QSSASDPTGA ASQLCQARET QVGSETKTLP 
       310        320        330        340        350
SVDVALLHSH GDSVGPGLSP YIQPNLAPSE APGQLGEKQV PSSTSDDRVK 
       360        370        380        390        400
DEFSDLSEGD VLSEDDSDKK QTPQSSDESF EPYPEKKVSG KKSEGKEAKR 
       410        420        430        440        450
PEEPKIRKKP GPKPGWKKKL RCEREELPTI YKCPYQGCTA VYRGADGMKK 
       460        470        480        490        500
HIKEHHEEVR ERPCPHPGCN KVFMIDRYLQ RHVKLIHTEV RNYICDECGQ 
       510        520        530        540        550
TFKQRKHLLV HQMRHSGAKP LQCEVCGFQC RQRASLKYHM TKHKAETELD 
       560        570        580        590        600
FACDQCGRRF EKAHNLNVHM SMVHPLTQTQ ALPLEAEPPP GPLSLAGTVE 

GQAVKPEPT

Length:609

Mass (Da):66,839

Last modified:May 3, 2011 - v1

Checksum:ⁱ686F1DA402D75171

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115273 Genomic DNA No translation available.
NCBI Reference Sequences More...RefSeqⁱ	XP_002725470.1, XM_002725424.5 XP_002728649.1, XM_002728603.5
UniGeneⁱ	Rn.140797

Genome annotation databases

Ensemblⁱ	ENSRNOT00000022324; ENSRNOP00000022324; ENSRNOG00000016631
GeneIDⁱ	307924
KEGGⁱ	rno:307924

Protein	Similar proteins		Species	Score	Length	Source
F1LN08	Zfp276 protein (Fragment)		RAT		555	UniRef100_F1LN08

Protein	Similar proteins		Species	Score	Length	Source
F1LN08	Zinc finger protein 276		MOUSE		614	UniRef90_Q8CE64
zinc finger protein 276 isoform X1		MESAU		617
Zinc finger protein		CRIGR		617
Uncharacterized protein		NEOLE		613
Zfp276 protein (Fragment)		RAT		555
+12

Protein	Similar proteins		Species	Score	Length	Source
F1LN08	Zinc finger protein 276		HUMAN		614	UniRef50_Q8N554
Zinc finger protein 276		MOUSE		614
Uncharacterized protein		Cebus capucinus imitator		616
ZNF276 isoform 4		PANTR		614
Uncharacterized protein		CERAT		613
+143

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC115273 Genomic DNA No translation available.
RefSeqⁱ	XP_002725470.1, XM_002725424.5 XP_002728649.1, XM_002728603.5
UniGeneⁱ	Rn.140797

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000022324

STRINGⁱ

10116.ENSRNOP00000022324

Proteomic databases

PaxDbⁱ	F1LN08
PRIDEⁱ	F1LN08

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000022324; ENSRNOP00000022324; ENSRNOG00000016631
GeneIDⁱ	307924
KEGGⁱ	rno:307924

Organism-specific databases

CTDⁱ	57247
RGDⁱ	1307469 Zfp276

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00530000063153
InParanoidⁱ	F1LN08
OMAⁱ	IQAVWGC
OrthoDBⁱ	EOG091G04WK
TreeFamⁱ	TF332664

Gene expression databases

Bgeeⁱ	ENSRNOG00000016631 Expressed in 9 organ(s), highest expression level in liver
Genevisibleⁱ	F1LN08 RN

Family and domain databases

InterProⁱ	View protein in InterPro IPR012934 Znf_AD IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF07776 zf-AD, 1 hit PF00096 zf-C2H2, 2 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 4 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	F1LN08_RAT
Accessionⁱ	F1LN08Primary (citable) accession number: F1LN08
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 3, 2011
	Last sequence update:	May 3, 2011
	Last modified:	November 7, 2018
	This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F1LN08 (F1LN08_RAT)

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Zinc finger protein (C2H2 type) 276

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ