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UniProtKB - F1LN08 (F1LN08_RAT)
Protein
Submitted name:
Zinc finger protein (C2H2 type) 276
Gene
Zfp276
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: RGD
- zinc ion binding Source: InterPro
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein (C2H2 type) 276Imported |
Gene namesi | Name:Zfp276Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1307469, Zfp276 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000016631, Expressed in liver and 20 other tissues |
Genevisiblei | F1LN08, RN |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 77 – 163 | ZADInterPro annotationAdd BLAST | 87 | |
Domaini | 462 – 492 | C2H2-typeInterPro annotationAdd BLAST | 31 | |
Domaini | 493 – 520 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 521 – 548 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 551 – 579 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 69 | DisorderedSequence analysisAdd BLAST | 69 | |
Regioni | 270 – 296 | DisorderedSequence analysisAdd BLAST | 27 | |
Regioni | 315 – 417 | DisorderedSequence analysisAdd BLAST | 103 | |
Regioni | 583 – 609 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 16 – 59 | Polar residuesSequence analysisAdd BLAST | 44 | |
Compositional biasi | 271 – 296 | Polar residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 343 – 417 | Basic and acidic residuesSequence analysisAdd BLAST | 75 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000158841 |
HOGENOMi | CLU_040755_0_0_1 |
InParanoidi | F1LN08 |
OMAi | LAVKWAW |
OrthoDBi | 1318335at2759 |
TreeFami | TF332664 |
Family and domain databases
InterProi | View protein in InterPro IPR012934, Znf_AD IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF07776, zf-AD, 1 hit PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS51915, ZAD, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
i Sequence
Sequence statusi: Complete.
F1LN08-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKRDRLGRFL SPGIARQRGS SGSSCGSGRT RGRPSRTGGS SADGAAPQLS
60 70 80 90 100
WGSTRSCGDT GEDGTDEAGA GRTLTMGHCR LCHGKFSSRS LRSISERVPG
110 120 130 140 150
ETSERLSPGE RVFIRDFQRL LGVAVHQDPA LPQFVCKNCY TQFYQCHSLL
160 170 180 190 200
RSFLQRVNVS PAGQRKPCTK VGVQPPTVAE EGACMADLIT SSPQCLHGLV
210 220 230 240 250
GWVHEHAVNC GCLPSLQRTL SSEYCGVIQA VWGCDQGHDF TMDTDSGCRA
260 270 280 290 300
LLLDSALAVK WGKELAPRLA QSSASDPTGA ASQLCQARET QVGSETKTLP
310 320 330 340 350
SVDVALLHSH GDSVGPGLSP YIQPNLAPSE APGQLGEKQV PSSTSDDRVK
360 370 380 390 400
DEFSDLSEGD VLSEDDSDKK QTPQSSDESF EPYPEKKVSG KKSEGKEAKR
410 420 430 440 450
PEEPKIRKKP GPKPGWKKKL RCEREELPTI YKCPYQGCTA VYRGADGMKK
460 470 480 490 500
HIKEHHEEVR ERPCPHPGCN KVFMIDRYLQ RHVKLIHTEV RNYICDECGQ
510 520 530 540 550
TFKQRKHLLV HQMRHSGAKP LQCEVCGFQC RQRASLKYHM TKHKAETELD
560 570 580 590 600
FACDQCGRRF EKAHNLNVHM SMVHPLTQTQ ALPLEAEPPP GPLSLAGTVE
GQAVKPEPT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC115273 Genomic DNA No translation available. |
RefSeqi | XP_002725470.1, XM_002725424.5 XP_002728649.1, XM_002728603.5 |
Genome annotation databases
Ensembli | ENSRNOT00000022324; ENSRNOP00000022324; ENSRNOG00000016631 |
GeneIDi | 307924 |
KEGGi | rno:307924 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC115273 Genomic DNA No translation available. |
RefSeqi | XP_002725470.1, XM_002725424.5 XP_002728649.1, XM_002728603.5 |
3D structure databases
SMRi | F1LN08 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000022324 |
Proteomic databases
PaxDbi | F1LN08 |
Genome annotation databases
Ensembli | ENSRNOT00000022324; ENSRNOP00000022324; ENSRNOG00000016631 |
GeneIDi | 307924 |
KEGGi | rno:307924 |
Organism-specific databases
CTDi | 57247 |
RGDi | 1307469, Zfp276 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000158841 |
HOGENOMi | CLU_040755_0_0_1 |
InParanoidi | F1LN08 |
OMAi | LAVKWAW |
OrthoDBi | 1318335at2759 |
TreeFami | TF332664 |
Gene expression databases
Bgeei | ENSRNOG00000016631, Expressed in liver and 20 other tissues |
Genevisiblei | F1LN08, RN |
Family and domain databases
InterProi | View protein in InterPro IPR012934, Znf_AD IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF07776, zf-AD, 1 hit PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 5 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS51915, ZAD, 1 hit PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | F1LN08_RAT | |
Accessioni | F1LN08Primary (citable) accession number: F1LN08 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 3, 2011 | |
Last modified: | January 19, 2022 | |
This is version 65 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |