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Entry version 71 (02 Jun 2021)
Sequence version 1 (03 May 2011)
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Protein
Submitted name:

Desmoplakin

Gene

Dsp

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-351906, Apoptotic cleavage of cell adhesion proteins
R-RNO-6798695, Neutrophil degranulation
R-RNO-6805567, Keratinization
R-RNO-6809371, Formation of the cornified envelope

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DesmoplakinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DspImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Rat genome database

More...
RGDi
1305794, Dsp

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F1LMV6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1LMV6

PRoteomics IDEntifications database

More...
PRIDEi
F1LMV6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F1LMV6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
F1LMV6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000013928, Expressed in esophagus and 20 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F1LMV6, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
F1LMV6, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000018649

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F1LMV6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini465 – 522SH3InterPro annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 20DisorderedSequence analysisAdd BLAST20
Regioni2817 – 2877DisorderedSequence analysisAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili144 – 164Sequence analysisAdd BLAST21
Coiled coili326 – 346Sequence analysisAdd BLAST21
Coiled coili418 – 448Sequence analysisAdd BLAST31
Coiled coili716 – 736Sequence analysisAdd BLAST21
Coiled coili1034 – 1054Sequence analysisAdd BLAST21
Coiled coili1062 – 1103Sequence analysisAdd BLAST42
Coiled coili1111 – 1159Sequence analysisAdd BLAST49
Coiled coili1178 – 1216Sequence analysisAdd BLAST39
Coiled coili1232 – 1280Sequence analysisAdd BLAST49
Coiled coili1313 – 1354Sequence analysisAdd BLAST42
Coiled coili1395 – 1443Sequence analysisAdd BLAST49
Coiled coili1473 – 1555Sequence analysisAdd BLAST83
Coiled coili1563 – 1688Sequence analysisAdd BLAST126
Coiled coili1696 – 1751Sequence analysisAdd BLAST56
Coiled coili1770 – 1811Sequence analysisAdd BLAST42
Coiled coili1819 – 1926Sequence analysisAdd BLAST108

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2818 – 2877Polar residuesSequence analysisAdd BLAST60

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the plakin or cytolinker family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0516, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154843

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000679_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1LMV6

Identification of Orthologs from Complete Genome Data

More...
OMAi
TTEITHH

Database of Orthologous Groups

More...
OrthoDBi
7016at2759

TreeFam database of animal gene trees

More...
TreeFami
TF106435

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.90.1290.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028462, Desmoplakin
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin

The PANTHER Classification System

More...
PANTHERi
PTHR23169, PTHR23169, 1 hit
PTHR23169:SF26, PTHR23169:SF26, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00681, Plectin, 8 hits
PF17902, SH3_10, 1 hit
PF18373, Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00250, PLEC, 18 hits
SM00150, SPEC, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF75399, SSF75399, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1LMV6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSCNGGSHPR INTLGRMTRA ESGPDLRYEM TYSGGGGGGG GGGGGTSRMY
60 70 80 90 100
YSRRCTVNDQ NSDGYCQTGT MSRHQNQNTI QELLQNCADC LMRAELIAQP
110 120 130 140 150
ELKFGEGIQL AWNRELDEYF TQANDQMEII DGLIREMRQM GQPCDAYQKR
160 170 180 190 200
LLQLQEQMRA LYKAISAPRV RRASSKGGYT CQSGSGWDEF TKRLTGECLG
210 220 230 240 250
WMRQQRAEMD LMAWGVDSGS VEQHINSHRS IHNAIGDYRW QLDKIKADLR
260 270 280 290 300
EKSAIYQLEE EYENLLKASF ERMDHLRQLQ NIIQATSREI MWINDCEEEE
310 320 330 340 350
LLYDWSDKNT NIAQKQEAFS IRMSQLEVKE KELNKLKQES DQLVLNQHPA
360 370 380 390 400
SDKIEAYMDT LQTQWSWILQ ITKCIDVHLK ENAAYFQFFE EAQSTEAYLK
410 420 430 440 450
GLQDSIRKKY PCDKNMPLQH LLEQIKELEK EREKILEYKR QVQNLVNKSK
460 470 480 490 500
KIVQLKPRNP DYRSNKPIIL RALCDYKQDQ KIVHKGDECI LKDNNERSKW
510 520 530 540 550
YVTGPGGVDM LVPSVGLIIP PPNPLAVDLS CKIEQYYEAI LALWNQLYIN
560 570 580 590 600
MKSLVSWHYC MIDIEKIRAM TIAKLKTMRQ EDYMKTIEDL ELHYQDFIKN
610 620 630 640 650
SQGSEMFGDD DKRRMQSQFT DAQKHYQTLV IQLPGHPQHQ TVTKTEITHV
660 670 680 690 700
GTCQDVNHNK VIETNRENDK QETWLLMELQ KIRRQMEHCE ARMTLKNLLL
710 720 730 740 750
TDQGSTHNIT VKINELKSVQ NDSQALAEVL NQLKDMLANF RGSEKYCYLQ
760 770 780 790 800
NEIFGLFQKL ENINGVTDGY LNSLCSVRAL LQAILQTEDM LKVYEARLTE
810 820 830 840 850
EETVCLDLDK VEAYRCGLKK IKNDLNLKKS LLATMKTELQ KAQQIHSQSS
860 870 880 890 900
QQYPLYDLDL GKFTEKVTQL TDRWQKIDKQ IDFRLWDLEK QIKQLRNYRD
910 920 930 940 950
NYQSFCKWLY DAKRRQDSLE SMKFGDSNTV MRFLNEQKNL HNEISGKRDK
960 970 980 990 1000
SEEVHKIAEL CANSIKDYEL QLASYTSGLE TLLNIPIKRT MVQSPSGVIL
1010 1020 1030 1040 1050
QEAADIHARY IELLTRSGDY YRFLSEMLKS LEDLKLKNTK IEVLEEELRL
1060 1070 1080 1090 1100
ARDANSENCN KNKFLDQNLQ KYQAECSQFK AKLVSLEELK RQAELDGKSA
1110 1120 1130 1140 1150
KQNLDKCYGQ IKELNEKITR LTYEIEDEKR RRKTVEDRFD QQKNDYDQLQ
1160 1170 1180 1190 1200
KARQCEKESL GWQKLESEKA IKEKEYEIER LRVLLQEEGA RKREYENELA
1210 1220 1230 1240 1250
KVRNHYNEEM SNLRNKYETE INITKTTIKE ISMQKEDDSK NLRNQLDRLS
1260 1270 1280 1290 1300
RENRDLKDEI VRLNDSILQA TEQRRRAEEN ALQQKACGSE IMQKKQHLEV
1310 1320 1330 1340 1350
ELKQVIQQRS EDNARHKQSL EEAAKTIQDK NKEIERLKAE YQEEAKRRWE
1360 1370 1380 1390 1400
YENELSKVRN SYDEEIISLR NKFETEINIT KTTIHQLTMQ KEEDTSGYRA
1410 1420 1430 1440 1450
QIDNLTRENR SLSEEVKRLK NTLAQTTENL RRVEENVQQQ KASGSEMSQR
1460 1470 1480 1490 1500
KQQLEIELRQ VSQMRTEESM RYKQSLDDAA KTIQDKNKEI ERLKQLVDKE
1510 1520 1530 1540 1550
TNERKCLEDE NSKLQRVQYD LQKANNSATE AMSKLKVQEQ ELTRLRIDYE
1560 1570 1580 1590 1600
RVSQERTVKD QDITRIQSSL KDLQLQKQKA EEELSRLKRT ASDESSKRKM
1610 1620 1630 1640 1650
LEEELEAMRR SLKEQAVKIT NLTQQLEQAS IVKKRSEDDL RQQRDVLDGH
1660 1670 1680 1690 1700
VREKQRTQEE LRRLSLDVEA LRRQLVQEQE NVKQAHLRNE HFQKAIEDKS
1710 1720 1730 1740 1750
RSLNESKIEI ERLQSLTENL TKEHLMLEEE LRNLRLEYDD LRRGRSEADN
1760 1770 1780 1790 1800
DKNSTISELR SQLQISNNRT LELQGLINDL QRERENLRQE IEKFQKQALE
1810 1820 1830 1840 1850
ASNRIQESKS QCTQVVQERE SLLVKIKVLE QDKARLQRLE DELNRAKATL
1860 1870 1880 1890 1900
EAETRVKQRL ECEKQQIQND LNQWKTQYSR KEETIRKIES EREKSEREKN
1910 1920 1930 1940 1950
SLRSEIERLQ AEIKRIEERC RRKLEDSTRE TQSQLETERC RLQKEIDKLR
1960 1970 1980 1990 2000
QRPYGSHRET QTEYEWTVDS SKLVFDGLRK KVTAMQLYEC QLIDKTTLDK
2010 2020 2030 2040 2050
LLKGKKSVEE VASEIQPFLR GAGAIAGASA SPKEKYSLVE AKRKKFITPE
2060 2070 2080 2090 2100
STVMLLEAQA ATGGIIDPHR NEKLTVDNAI ARDLIDFDDR QQIYTAEKAI
2110 2120 2130 2140 2150
TGFDDPFSGK TVSVSEAIKK NLIDRETGMR LLEAQLASGG VVDPVNSVFL
2160 2170 2180 2190 2200
PKDVALARGL IDRDLYRSLN DPRDSQKNFV DPITKKKVSY MQLRERCRIE
2210 2220 2230 2240 2250
PHTGLLLLSV QKRSMSFQGI RQPVTVTELV DSGILRPSTV NELESGQISY
2260 2270 2280 2290 2300
DEVGERIKDF LQGSSCIAGI YNETTKQKLG IYEAMKIGLV RPGTALELLE
2310 2320 2330 2340 2350
AQAATGFIVD PVSNLRLPVE EAYKRGLVGI EFKEKLLSAE RAVTGYNDPE
2360 2370 2380 2390 2400
TGNIISLFQA MNKELIEKGH GIRLLEAQIA TGGIIDPKES HRLPVDMAYK
2410 2420 2430 2440 2450
RGYFNEELSE ILSDPSDDTK GFFDPNTEEN LTYLQLKERC IKDEETGLCL
2460 2470 2480 2490 2500
LPLKEKKKQV QTSQKNTLRK RRVVIVDPET NKEMSVQEAY KKGLIDYETF
2510 2520 2530 2540 2550
KELCEQECEW EEITITGSDG STRVVLVDRK TGSQYDIQDA IDKGLVDRKF
2560 2570 2580 2590 2600
FDQYRSGSLS LTQFADMISL KNGVGTSSGL SGSVNDDVFS SSRHESVSKI
2610 2620 2630 2640 2650
STISSVRNLT IRSSSLSDPL EESSPIAAIF DTENLEKISI TEGIERGIVD
2660 2670 2680 2690 2700
SITGQRLLEA QACTGGIIHP TTGQKLSLQD AVSQGLIDQD MATRLKPAQK
2710 2720 2730 2740 2750
AFIGFEGVKG KKKMSAAEAV KEKWLPYEAG QRFLEFQFLT GGLVDPEVHG
2760 2770 2780 2790 2800
RISTEEAIRK GFIDGRAAQR LQDISSYAKI LTCPKTKLKI SYKDAMNRSM
2810 2820 2830 2840 2850
VEDITGLRLL EAASVSSKGL PSPYNMSAPG SRSGSRSGSR SGSRSGSRSG
2860 2870
SRRGSFDATG NSSYSYSYSF SSSSIGY
Length:2,877
Mass (Da):332,393
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC447D421E029C01B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AABR07027383 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_001058477.1, XM_001058477.6
XP_225259.4, XM_225259.9

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000018649; ENSRNOP00000018649; ENSRNOG00000013928

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
306871

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07027383 Genomic DNA No translation available.
RefSeqiXP_001058477.1, XM_001058477.6
XP_225259.4, XM_225259.9

3D structure databases

SMRiF1LMV6
ModBaseiSearch...

Protein-protein interaction databases

IntActiF1LMV6, 2 interactors
STRINGi10116.ENSRNOP00000018649

PTM databases

iPTMnetiF1LMV6
PhosphoSitePlusiF1LMV6

Proteomic databases

jPOSTiF1LMV6
PaxDbiF1LMV6
PRIDEiF1LMV6

Genome annotation databases

EnsembliENSRNOT00000018649; ENSRNOP00000018649; ENSRNOG00000013928
GeneIDi306871

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1832
RGDi1305794, Dsp

Phylogenomic databases

eggNOGiKOG0516, Eukaryota
GeneTreeiENSGT00940000154843
HOGENOMiCLU_000679_1_0_1
InParanoidiF1LMV6
OMAiTTEITHH
OrthoDBi7016at2759
TreeFamiTF106435

Enzyme and pathway databases

ReactomeiR-RNO-351906, Apoptotic cleavage of cell adhesion proteins
R-RNO-6798695, Neutrophil degranulation
R-RNO-6805567, Keratinization
R-RNO-6809371, Formation of the cornified envelope

Gene expression databases

BgeeiENSRNOG00000013928, Expressed in esophagus and 20 other tissues
GenevisibleiF1LMV6, RN

Family and domain databases

Gene3Di3.90.1290.10, 3 hits
InterProiView protein in InterPro
IPR028462, Desmoplakin
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
PANTHERiPTHR23169, PTHR23169, 1 hit
PTHR23169:SF26, PTHR23169:SF26, 1 hit
PfamiView protein in Pfam
PF00681, Plectin, 8 hits
PF17902, SH3_10, 1 hit
PF18373, Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00250, PLEC, 18 hits
SM00150, SPEC, 2 hits
SUPFAMiSSF75399, SSF75399, 4 hits
PROSITEiView protein in PROSITE
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1LMV6_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1LMV6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 2, 2021
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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