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Entry version 35 (10 Apr 2019)
Sequence version 1 (03 May 2011)
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Protein
Submitted name:

Transketolase, related

Gene

NCLIV_011210

Organism
Neospora caninum (strain Liverpool)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transketolase, relatedImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:NCLIV_011210Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNeospora caninum (strain Liverpool)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri572307 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaSarcocystidaeNeospora

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
ToxoDB:NCLIV_011210

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

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STRINGi
29176.XP_003880687.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
F0VAG5

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini334 – 354TRANSKETOLASE_1InterPro annotationAdd BLAST21

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG0523 Eukaryota
COG0021 LUCA

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
F0VAG5

Database of Orthologous Groups

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OrthoDBi
354970at2759

Family and domain databases

Conserved Domains Database

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CDDi
cd02012 TPP_TK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.50.920, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005475 Transketolase-like_Pyr-bd
IPR020826 Transketolase_BS
IPR033248 Transketolase_C
IPR033247 Transketolase_fam
IPR005474 Transketolase_N

The PANTHER Classification System

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PANTHERi
PTHR43522 PTHR43522, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF02779 Transket_pyr, 1 hit
PF02780 Transketolase_C, 1 hit
PF00456 Transketolase_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00861 Transket_pyr, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF52518 SSF52518, 2 hits
SSF52922 SSF52922, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00801 TRANSKETOLASE_1, 1 hit
PS00802 TRANSKETOLASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F0VAG5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METGPQVVPR SLPRHQALFP GNPPKIRSSR LTVQIASCAS PGERTATTSE
60 70 80 90 100
PLLANAPETQ RDTGACRRLS LCGATLPSRV LCFLPATRNL RSRSRALHSA
110 120 130 140 150
TKRASTQPIR PEISPPRQLF TSVGNSERTT PTKTRTSRMP SSTCFASPSL
160 170 180 190 200
GPRKRAFVSR RCQRSKNCAL SNTGPTTSSA KKQTPCKTHT CSGNCGRSNE
210 220 230 240 250
KLTCPPSSPE SHSPVDGPVS ASQENLFLPE RTQPHLASRR HLRPSAFSLS
260 270 280 290 300
FCRFFPLFIF RLSFFVRLER VAAFVFNFAS LSPHCSLALR PSIVKRRGSN
310 320 330 340 350
AQLGEANSQP ETKKLSPGKR ETASTDVLCV NTIRCLGADL PTIANSGHPG
360 370 380 390 400
APMGMAPMAH ALWGYVMRYS GKHPRWFNRD RFILSNGHAC ALLYSMLHLT
410 420 430 440 450
ARRLRRDNRG SAPVSPAEQQ NAGTSRGALR GGHRNDDGNA VGIALAGQYM
460 470 480 490 500
GAKYNKENFP IFDSHVFVFC GDGCLEEGVA SEACSLAGHL GLHRLIVLYD
510 520 530 540 550
ENNITIDGEV NLAFSEKVQQ RFKAYDWHVD VVADGNHDVA GLVRTMEAAK
560 570 580 590 600
KRTDKPTLIC VRTTIGFLSS KEGTAKVHGS PLSEDDLRKV KEKCGLNPDE
610 620 630 640 650
KLQVPDAVKK FYEEVQERGE RAVAEWNALF DKYKTAYPEE AKEIERMFSR
660 670 680 690 700
EVRPEVFETL KQLGDKAREK GDSTRAHSGR MLNGIKGFMP ELIGGSADLT
710 720 730 740 750
GSNCTDLQNE KSFQVANRSG RYIHFGVREH AMIAMANGMY HFGCMRPFCA
760 770 780 790 800
TFLNFVTYGW GATRLAALAK CGILLVATHD SIELGQDGPT HQPIEVLALC
810 820 830 840 850
RATPELIAIR PADGTEVAGA YAVWLRDELK RVTLLSLCRS TVPVLEGSSF
860 870 880 890 900
DGVALGAYIL SDFENNGKKK VVIAGSGSEV HLCVEAKKLL TGNWDVRLVS
910 920 930 940 950
MPCWTLFDEQ PAEYRNKILC LSERKNGNVL TAYVEAASTF GWDKYFDVHV
960 970 980
GMQSFGASAP GKALYDFFGF SPASIAKKIE EYKPPF
Length:986
Mass (Da):108,289
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4BB3038D78C3B0AB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FR823384 Genomic DNA Translation: CBZ50654.1

NCBI Reference Sequences

More...
RefSeqi
XP_003880687.1, XM_003880638.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
13441683

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR823384 Genomic DNA Translation: CBZ50654.1
RefSeqiXP_003880687.1, XM_003880638.1

3D structure databases

ProteinModelPortaliF0VAG5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi29176.XP_003880687.1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi13441683

Organism-specific databases

EuPathDBiToxoDB:NCLIV_011210

Phylogenomic databases

eggNOGiKOG0523 Eukaryota
COG0021 LUCA
InParanoidiF0VAG5
OrthoDBi354970at2759

Family and domain databases

CDDicd02012 TPP_TK, 1 hit
Gene3Di3.40.50.920, 1 hit
InterProiView protein in InterPro
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005475 Transketolase-like_Pyr-bd
IPR020826 Transketolase_BS
IPR033248 Transketolase_C
IPR033247 Transketolase_fam
IPR005474 Transketolase_N
PANTHERiPTHR43522 PTHR43522, 1 hit
PfamiView protein in Pfam
PF02779 Transket_pyr, 1 hit
PF02780 Transketolase_C, 1 hit
PF00456 Transketolase_N, 1 hit
SMARTiView protein in SMART
SM00861 Transket_pyr, 1 hit
SUPFAMiSSF52518 SSF52518, 2 hits
SSF52922 SSF52922, 1 hit
PROSITEiView protein in PROSITE
PS00801 TRANSKETOLASE_1, 1 hit
PS00802 TRANSKETOLASE_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF0VAG5_NEOCL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F0VAG5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: April 10, 2019
This is version 35 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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