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Entry version 46 (08 May 2019)
Sequence version 1 (05 Apr 2011)
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Protein

Uncharacterized protein C16orf96 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C16orf96 homologCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1926059 4930562C15Rik

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004135391 – 1145Uncharacterized protein C16orf96 homologAdd BLAST1145

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9QMW4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9QMW4

PRoteomics IDEntifications database

More...
PRIDEi
E9QMW4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9QMW4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9QMW4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000022518 Expressed in 37 organ(s), highest expression level in testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9QMW4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9QMW4 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000097784

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9QMW4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili74 – 101Sequence analysisAdd BLAST28
Coiled coili186 – 212Sequence analysisAdd BLAST27
Coiled coili744 – 816Sequence analysisAdd BLAST73

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi360 – 442Pro-richAdd BLAST83
Compositional biasi582 – 636Ala-richAdd BLAST55

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJ37 Eukaryota
ENOG4112C1S LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162979

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000202728

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9QMW4

Database of Orthologous Groups

More...
OrthoDBi
430976at2759

TreeFam database of animal gene trees

More...
TreeFami
TF339506

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032013 DUF4795

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16043 DUF4795, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: E9QMW4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSFSITFTEL VNVAIPQCGV VNFKALHLLL QGILEHIQIT ELKKVLSGEE
60 70 80 90 100
DFLQSSPAVF IPREGDAQPV INPMKRLSNI FDQVVDRIEK IESKLAEMQD
110 120 130 140 150
IPTTSQLVEE SYGDKRPAEE MWNNIKIQKR IEGNEKATEK FTRTLQDLLN
160 170 180 190 200
DLHVLKGSVE TVQKDVDTIK FIFEKVNPQK LELLGDDLKT QSRKLGALQR
210 220 230 240 250
EVVTLQNKVR AVPQPEEMVL WSGLHEAMFS PEQQKLEVEP SGVWQSMVSL
260 270 280 290 300
PGSPLEQPED AGYIHIPIHS ATPVPTMVQL GTTGALREEE LTRAVELADS
310 320 330 340 350
QRPELAQAFV SQTQRLERAQ ASVSQTQRLE RAQASVSQTQ RLERAQASVS
360 370 380 390 400
QTQNLRQTAP FPFPVPGFVP GPDFMPVYGP RPGMATPSAW ALPRGLARGN
410 420 430 440 450
YWPIWGIGPY QPGQGPLQPM GPMPRVPFPA MGSDIPWTQP LPQGTQWYPN
460 470 480 490 500
IEERGPEYEE QYPEGYQEEM PMDEAPQEEM AVYGALEEEI PTEGAPQDGI
510 520 530 540 550
PKGRARERIS KEKVPKYRTP KERVSYHKAS KDVSPEDTGT KDEAPEVKVL
560 570 580 590 600
KKVVYKDRPQ KDKAPEPRRK GPSSAIKKLR SAIASAAAAA AAYAAHANSA
610 620 630 640 650
AQLAKDAVKA IQDVPANQLA AKAALIASSG PLGAFADFLG AGFGHGATSN
660 670 680 690 700
TPFDEGELEE FPEEFAAPFN PFTSKPVLSQ AMISATQATS PEEKKKAVQY
710 720 730 740 750
SMGHIAQMPS RHNSLKEEFT NLSTTLNQRL NYLANMGSSG VLGSTVNVLE
760 770 780 790 800
EKIINLQKAR LQEEELERVW GHQIDTMKSH YMVLDRAVER LQIRMDDLKI
810 820 830 840 850
LKAEIERLDL VKADKNVMDL ELNEKANRDA LASKANRVDL ETVAMELNEM
860 870 880 890 900
IHSMLLKITN YESDWKKALK HLRKDLNTKL VQSDLNSLKK DIEEVWKVVR
910 920 930 940 950
KLLLEGLRFD PDSAAGFKKK LFERVKCISC DRPVEMMTGP QLITIRNTHG
960 970 980 990 1000
LSRIRPASAN SYEYLQRQLI REQQQHLHFQ NFGVHEEGQG FQKDWGDGPR
1010 1020 1030 1040 1050
NENTLKHKSH DLSTLYPYGD PELMNYDTAE VDILGVDGVL YKGRMSSQFG
1060 1070 1080 1090 1100
TRTGEKDIAA VKVSYYTIPN LTDRVRPGSL LAPGYPPLSP RTSITSATTL
1110 1120 1130 1140
HSATNTTTAR PPSLPPVPQL PPLIPVSRDT QEAPGSAKRL KSPRL
Length:1,145
Mass (Da):127,660
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3422DB0A6B3B210B
GO
Isoform 2 (identifier: E9QMW4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     800-1145: ILKAEIERLD...SAKRLKSPRL → VRRSEDQEGG...IKNKSQGLER

Note: No experimental confirmation available.
Show »
Length:852
Mass (Da):94,439
Checksum:i311B277759D199C3
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6H692A6H692_MOUSE
4930562C15Rik protein
4930562C15Rik
306Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QWH1M0QWH1_MOUSE
RIKEN cDNA 4930562C15 gene
4930562C15Rik
125Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BJT7H3BJT7_MOUSE
RIKEN cDNA 4930562C15 gene
4930562C15Rik
43Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAE21617 differs from that shown. Reason: Frameshift at position 245.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_042127800 – 1145ILKAE…KSPRL → VRRSEDQEGGTGELLLGTTR PSSKGLQNTGELDNILFCIN YTSIKNKSQGLER in isoform 2. CuratedAdd BLAST346

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC167018 Genomic DNA No translation available.
AK133365 mRNA Translation: BAE21617.1 Frameshift.

NCBI Reference Sequences

More...
RefSeqi
NP_084468.1, NM_030192.1 [E9QMW4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000100211; ENSMUSP00000097784; ENSMUSG00000022518 [E9QMW4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
78809

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:78809

UCSC genome browser

More...
UCSCi
uc007yam.1 mouse [E9QMW4-2]
uc012aav.1 mouse [E9QMW4-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC167018 Genomic DNA No translation available.
AK133365 mRNA Translation: BAE21617.1 Frameshift.
RefSeqiNP_084468.1, NM_030192.1 [E9QMW4-1]

3D structure databases

SMRiE9QMW4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097784

PTM databases

iPTMnetiE9QMW4
PhosphoSitePlusiE9QMW4

Proteomic databases

MaxQBiE9QMW4
PaxDbiE9QMW4
PRIDEiE9QMW4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000100211; ENSMUSP00000097784; ENSMUSG00000022518 [E9QMW4-1]
GeneIDi78809
KEGGimmu:78809
UCSCiuc007yam.1 mouse [E9QMW4-2]
uc012aav.1 mouse [E9QMW4-1]

Organism-specific databases

MGIiMGI:1926059 4930562C15Rik

Phylogenomic databases

eggNOGiENOG410IJ37 Eukaryota
ENOG4112C1S LUCA
GeneTreeiENSGT00940000162979
HOGENOMiHOG000202728
InParanoidiE9QMW4
OrthoDBi430976at2759
TreeFamiTF339506

Miscellaneous databases

Protein Ontology

More...
PROi
PR:E9QMW4

Gene expression databases

BgeeiENSMUSG00000022518 Expressed in 37 organ(s), highest expression level in testis
ExpressionAtlasiE9QMW4 baseline and differential
GenevisibleiE9QMW4 MM

Family and domain databases

InterProiView protein in InterPro
IPR032013 DUF4795
PfamiView protein in Pfam
PF16043 DUF4795, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCP096_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9QMW4
Secondary accession number(s): Q3V087
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: April 5, 2011
Last modified: May 8, 2019
This is version 46 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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