Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 25 of 32  Show
  1. 1
    Category: Sequences.
    Strain: C57BL/6J.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 43321 other entries.

  2. 2
    "A three-allele model for the Pulmonary adenoma resistance 2 (Par2) locus in mice."
    Manenti G.
    Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Strain: C57BL6/J.
    Tissue: Lung.
    Source: UniProtKB/TrEMBL (unreviewed).
  3. 3
    Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6J.
    Source: UniProtKB/TrEMBL (unreviewed).
  4. 4
    "Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta."
    McDonald J.P., Rapic-Otrin V., Epstein J.A., Broughton B.C., Wang X., Lehmann A.R., Wolgemuth D.J., Woodgate R.
    Genomics 60:20-30(1999) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1347081.

    This publication is cited by 1 and mapped to 11 other entries.

  5. 5
    Category: Sequences.
    Source: MGI:1347081.

    This publication is cited by 16980 and mapped to 30200 other entries.

  6. 6
    "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R., Suzuki H., Yamanaka I., Kiyosawa H., Yagi K., Tomaru Y., Hasegawa Y., Nogami A., Schonbach C., Gojobori T.
    Hayashizaki Y.
    Nature 420:563-573(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1347081.

    This publication is cited by 16983 and mapped to 41374 other entries.

  7. 7
    "Constitutive and regulated expression of the mouse Dinb (Polkappa) gene encoding DNA polymerase kappa."
    Velasco-Miguel S., Richardson J.A., Gerlach V.L., Lai W.C., Gao T., Russell L.D., Hladik C.L., White C.L., Friedberg E.C.
    DNA Repair (Amst.) 2:91-106(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Source: MGI:1347081.

    This publication is mapped to 42 other entries.

  8. 8
    "Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2."
    Lee G.H., Nishimori H., Sasaki Y., Matsushita H., Kitagawa T., Tokino T.
    Oncogene 22:2374-2382(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1347081.

    This publication is mapped to 12 other entries.

  9. 9
    "129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation."
    McDonald J.P., Frank E.G., Plosky B.S., Rogozin I.B., Masutani C., Hanaoka F., Woodgate R., Gearhart P.J.
    J. Exp. Med. 198:635-643(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Data suggest that either DNA polymerase iota does not participate in hypermutation or its role is nonessential and can be readily assumed by another low-fidelity polymerase. [GeneRIF:26447].
    Source: MGI:1347081, GeneRIF:26447.

    This publication is mapped to 12 other entries.

  10. 10
    Category: Pathology & Biotech.
    Source: MGI:1347081.

    This publication is mapped to 39570 other entries.

  11. 11
    "Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis."
    Guo C., Fischhaber P.L., Luk-Paszyc M.J., Masuda Y., Zhou J., Kamiya K., Kisker C., Friedberg E.C.
    EMBO J. 22:6621-6630(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: MGI:1347081.

    This publication is cited by 4 and mapped to 54 other entries.

  12. 12
    "Pol iota is a candidate for the mouse pulmonary adenoma resistance 2 locus, a major modifier of chemically induced lung neoplasia."
    Wang M., Devereux T.R., Vikis H.G., McCulloch S.D., Holliday W., Anna C., Wang Y., Bebenek K., Kunkel T.A., Guan K., You M.
    Cancer Res. 64:1924-1931(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Nucleotide polymorphisms in DNA polymerase iota is associated with lung tumorigenesis in mouse and humans.
    Source: GeneRIF:26447.

    This publication is mapped to 11 other entries.

  13. 13
    "Contribution of DNA polymerase eta to immunoglobulin gene hypermutation in the mouse."
    Delbos F., De Smet A., Faili A., Aoufouchi S., Weill J.C., Reynaud C.A.
    J. Exp. Med. 201:1191-1196(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Source: MGI:1347081.

    This publication is mapped to 15 other entries.

  14. 14
    "Analysis of the Par2 modifier of pulmonary adenoma formation in mice."
    Wang M., Wang Y., You M., Devereux T.R.
    Exp. Lung Res. 31:193-204(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1347081.

    This publication is mapped to 24 other entries.

  15. 15
    "Normal immunoglobulin gene somatic hypermutation in Pol kappa-Pol iota double-deficient mice."
    Shimizu T., Azuma T., Ishiguro M., Kanjo N., Yamada S., Ohmori H.
    Immunol. Lett. 98:259-264(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Pol kappa and Pol iota double-deficient mice had the normal somatic hypermutation frequency. [GeneRIF:26447].
    Source: MGI:1347081, GeneRIF:26447.

    This publication is mapped to 29 other entries.

  16. 16
    "Genetic linkage between Pol iota deficiency and increased susceptibility to lung tumors in mice."
    Lee G.H., Matsushita H.
    Cancer Sci. 96:256-259(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Pol iota gene may participate in error-free repair of damaged DNA and prevention of lung tumor development. [GeneRIF:26447].
    Source: MGI:1347081, GeneRIF:26447.

    This publication is mapped to 13 other entries.

  17. 17
    "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Source: MGI:1347081.

    This publication is cited by 10626 and mapped to 43943 other entries.

  18. 18
    "Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis."
    Bienko M., Green C.M., Crosetto N., Rudolf F., Zapart G., Coull B., Kannouche P., Wider G., Peter M., Lehmann A.R., Hofmann K., Dikic I.
    Science 310:1821-1824(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: identification of two previously unknown ubiquitin-binding domains in the Y-family translesion synthesis polymerases that enable them to interact with monoubiquitinated targets and undergo monoubiquitination in vivo. [GeneRIF:26447].
    Source: MGI:1347081, GeneRIF:26447.

    This publication is cited by 1 and mapped to 36 other entries.

  19. 19
    "Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota."
    Martomo S.A., Yang W.W., Vaisman A., Maas A., Yokoi M., Hoeijmakers J.H., Hanaoka F., Woodgate R., Gearhart P.J.
    DNA Repair (Amst.) 5:392-398(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Source: MGI:1347081.

    This publication is mapped to 15 other entries.

  20. 20
    "UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota."
    Ohkumo T., Kondo Y., Yokoi M., Tsukamoto T., Yamada A., Sugimoto T., Kanao R., Higashi Y., Kondoh H., Tatematsu M., Masutani C., Hanaoka F.
    Mol. Cell. Biol. 26:7696-7706(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: suggest the involvement of the Pol eta and Pol iota proteins in UV-induced skin carcinogenesis. [GeneRIF:26447].
    Source: MGI:1347081, GeneRIF:26447.

    This publication is mapped to 16 other entries.

  21. 21
    "Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer."
    Dumstorf C.A., Clark A.B., Lin Q., Kissling G.E., Yuan T., Kucherlapati R., McGregor W.G., Kunkel T.A.
    Proc. Natl. Acad. Sci. U.S.A. 103:18083-18088(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Although pol iota deficiency alone had no effect UV-induced skin tumors in pol eta-deficient mice developed 4 weeks earlier in mice concomitantly deficient in pol iota. [GeneRIF:26447].
    Source: MGI:1347081, GeneRIF:26447.

    This publication is mapped to 16 other entries.

  22. 22
    "Effect of human cell malignancy on activity of DNA polymerase iota."
    Kazakov A.A., Grishina E.E., Tarantul V.Z., Gening L.V.
    Biochemistry Mosc. 75:905-911(2010) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: In the presence of Mg2+ the enzyme was active only in testicles and brain whereas in the presence of Mn2+ the activity was found in all organs.
    Source: GeneRIF:26447.

    This publication is mapped to 14 other entries.

  23. 23
    "Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitin."
    Burschowsky D., Rudolf F., Rabut G., Herrmann T., Peter M., Matthias P., Wider G.
    J. Biol. Chem. 286:1364-1373(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: Upon DNA damage the UBDs (UBM domains) of polymerase iota (Pol iota) interact with ubiquitinated proliferating cell nuclear antigen to regulate the interchange between processive DNA polymerases and translesional synthesis.
    Source: GeneRIF:26447.

    This publication is mapped to 14 other entries.

  24. 24
    "The roles of DNA polymerases kappa and iota in the error-free bypass of N2-carboxyalkyl-2'-deoxyguanosine lesions in mammalian cells."
    Yuan B., You C., Andersen N., Jiang Y., Moriya M., O'Connor T.R., Wang Y.
    J. Biol. Chem. 286:17503-17511(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: in mammalian cells both polymerases kappa and iota are necessary for the error-free bypass of N(2)-CEdG and N(2)-CMdG.
    Source: GeneRIF:26447.

    This publication is mapped to 34 other entries.

  25. 25
    "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
    Gaudet P., Livstone M.S., Lewis S.E., Thomas P.D.
    Brief. Bioinformatics 12:449-462(2011) [PubMed] [Europe PMC] [Abstract]
    Source: MGI:1347081.

    This publication is mapped to 58836 other entries.

1 to 25 of 32  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again