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Protein
Submitted name:

Cadherin 15, type 1, M-cadherin (myotubule)

Gene

cdh15

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Cadherins are calcium-dependent cell adhesion proteins.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionUniRule annotationSAAS annotation
LigandCalciumUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-DRE-375170 CDO in myogenesis
R-DRE-418990 Adherens junctions interactions

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin 15, type 1, M-cadherin (myotubule)Imported
Gene namesi
Name:cdh15Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-030131-780 cdh15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei594 – 621HelicalSequence analysisAdd BLAST28

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500324465120 – 792Sequence analysisAdd BLAST773

Expressioni

Gene expression databases

BgeeiENSDARG00000068191
ExpressionAtlasiE9QEL7 baseline

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 146CAInterPro annotationAdd BLAST86
Domaini170 – 261CAInterPro annotationAdd BLAST92
Domaini284 – 373CAInterPro annotationAdd BLAST90
Domaini396 – 477CAInterPro annotationAdd BLAST82
Domaini499 – 581CAInterPro annotationAdd BLAST83

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00760000118906
KOiK06809
OMAiLKDGWYR

Family and domain databases

Gene3Di4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
IPR000233 Cadherin_cytoplasmic-dom
IPR027397 Catenin_binding_dom_sf
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF01049 Cadherin_C, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 1 hit

Sequencei

Sequence statusi: Complete.

E9QEL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAVVVLAAL LTIVCQVSSS RLKQSDANPA VLNPWRHRVK RDWIIPPIRV
60 70 80 90 100
LENSKHLPED LVQIKSDKIF TGEVIYMLEG PGVDQDPKGL FEIDEKTGWI
110 120 130 140 150
KSKEPLDREK HKSFKLKAFA LSPSGERLES PTTIEIYVLD QNDNRPEFTQ
160 170 180 190 200
KEFIGTIPEF SVPGTSVMQV TAVDFDDPST DNAALSYSII GQECDPPHGI
210 220 230 240 250
NKTMFGINNK TGVIYIRDVG LDRDVVQSFR LTLQVADMSG MGLTSSSRAI
260 270 280 290 300
IHISDINNHA PKFQPTTYNM YAMENKLIAE VGRVNATDKD QRGGDNWRIK
310 320 330 340 350
YTIVNPSGHF AIRTDPVSNQ GIISVVKSLD YEYQAEYKLI VKAENEVKLK
360 370 380 390 400
SPYEQIHSAT VTVRVMNENE APIFYKNPIK VTVPESVVPG TILVSDIAHD
410 420 430 440 450
PDHAKLRFEI IQDPDEWLAI DHSTGQIMAK KNFKIRSPFV RNNIYSAVVK
460 470 480 490 500
VTDQDADGIS ATATLEVNLW ETNDYPPLLI PQSGTVCSDR DPDKLGLLLS
510 520 530 540 550
ALDEDMSPQA DPFTFNIADQ NMAANWTIIT LNETHAVLQP LVDIERGEFS
560 570 580 590 600
IPVVVSDSGS PSLYSSALVN VTVCPCDSFG DCKSITAAIF GSKIGISFIA
610 620 630 640 650
LMIIIGCIAL LLVLLLLTVA VRSCTSQNIR KGGGLLVGGS DDDIRDNVFH
660 670 680 690 700
YDEQGGGEED EEAFNIDFLR SPSDMLPAPA SFFPQDCGLP RGKQPLRKDA
710 720 730 740 750
PHYLPSPTYP RKPPGDPTDI EDFINVGLDA ADNDPNVPPY DTALIYDYEG
760 770 780 790
DGSVAGSLSS IASTGSDGDQ DYDYLNDWGP RFKKLANMYD PR
Length:792
Mass (Da):87,376
Last modified:April 5, 2011 - v1
Checksum:iA2F4DB99F8FB2BFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954648 Genomic DNA No translation available.
RefSeqiNP_997771.2, NM_212606.2
UniGeneiDr.77096

Genome annotation databases

EnsembliENSDART00000098453; ENSDARP00000089224; ENSDARG00000068191
GeneIDi565617
KEGGidre:565617

Similar proteinsi

Entry informationi

Entry nameiE9QEL7_DANRE
AccessioniPrimary (citable) accession number: E9QEL7
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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