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Protein
Submitted name:

Dentin sialophosphoprotein

Gene

Dspp

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-3000178 ECM proteoglycans

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dentin sialophosphoproteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DsppImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:109172 Dspp

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 17Sequence analysisAdd BLAST17
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500324453218 – 945Sequence analysisAdd BLAST928

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
E9Q9Z9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000053268 Expressed in 9 organ(s), highest expression level in molar tooth

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9Q9Z9 MM

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JAJ8 Eukaryota
ENOG4111CIV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111489

Identification of Orthologs from Complete Genome Data

More...
OMAi
DFDDESM

Database of Orthologous Groups

More...
OrthoDBi
1162130at2759

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9Q9Z9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKMKIIIYIC IWATAWAIPV PQLVPLERDI VENSVAVPLL THPGTAAQNE
60 70 80 90 100
LSINSTTSNS NDSPDGSEIG EQVLSEDGYK RDGNGSESIH VGGKDFPTQP
110 120 130 140 150
ILVNEQGNTA EEHNDIETYG HDGVHARGEN STANGIRSQV GIVENAEEAE
160 170 180 190 200
SSVHGQAGQN TKSGGASDVS QNGDATLVQE NEPPEASIKN STNHEAGIHG
210 220 230 240 250
SGVATHETTP QREGLGSENQ GTEVTPSIGE DAGLDDTDGS PSGNGVEEDE
260 270 280 290 300
DTGSGDGEGA EAGDGRESHD GTKGQGGQSH GGNTDHRGQS SVSTEDDDSK
310 320 330 340 350
EQEGFPNGHN GDNSSEENGV EEGDSTQATQ DNQKLSPKDT RDAEGGIISQ
360 370 380 390 400
SEACPSGKSQ DQGIETEGPN KGNKSIITKE SGKLSGSKDS NGHQGVELDK
410 420 430 440 450
RNSPKQGESD KPQGTAEKSA AHSNLGHSRI GSSSNSDGHD SYEFDDESMQ
460 470 480 490 500
GDDPKSSDES NGSDESDTNS ESANESGSRG DASYTSDESS DDDNDSDSHA
510 520 530 540 550
GEDDSSDDSS DTDDSDSNGD GDSDSNGDGD SESEDKDESD SSDHDNSSDS
560 570 580 590 600
ESKSDSSDSS DDSSDSSDSS DSSDSSDSSD SSDSSDSSDS SDSNSSSDSS
610 620 630 640 650
DSSSSSDSSD SSDSSDSSDS SDSSDSSDSS DSSDSSDSSD SSDSSDSSDS
660 670 680 690 700
SSSSDSSDSS SSSDSSDSSD SSDSSDSSDS SDSSSSDSSS SSNSSDSSDS
710 720 730 740 750
SDSSSSSDSS NSSDSSDSSD SSDSSDSSDS SNSSDSSDSS SSSDSSDSSS
760 770 780 790 800
SSDSSDSSDS SDSSESSESS DSSNSSDSSD SSDSSDSSDS SDSSDSSDSS
810 820 830 840 850
DSSNSSDSSD SSDSSDSSDS SNSSDSSDSS DSSDSSDSSD SSDSSDSSDS
860 870 880 890 900
SDSSDSSDSS DSSDSSDSSD SSDSSDSSDS SDSSDSSDSS NSSDSSDSDS
910 920 930 940
KDSSSDSSDG DSKSGNGNSD SNSDSNSDSD SDSEGSDSNH STSDD
Length:945
Mass (Da):95,125
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i62ACEC9E93256782
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P97399DSPP_MOUSE
Dentin sialophosphoprotein
Dspp Dmp3
934Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC164587 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_034210.2, NM_010080.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.319832

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000112771; ENSMUSP00000108391; ENSMUSG00000053268

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
666279

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:666279

UCSC genome browser

More...
UCSCi
uc008ykd.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164587 Genomic DNA No translation available.
RefSeqiNP_034210.2, NM_010080.3
UniGeneiMm.319832

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Proteomic databases

PRIDEiE9Q9Z9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000112771; ENSMUSP00000108391; ENSMUSG00000053268
GeneIDi666279
KEGGimmu:666279
UCSCiuc008ykd.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1834
MGIiMGI:109172 Dspp

Phylogenomic databases

eggNOGiENOG410JAJ8 Eukaryota
ENOG4111CIV LUCA
GeneTreeiENSGT00730000111489
OMAiDFDDESM
OrthoDBi1162130at2759

Enzyme and pathway databases

ReactomeiR-MMU-3000178 ECM proteoglycans

Miscellaneous databases

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000053268 Expressed in 9 organ(s), highest expression level in molar tooth
GenevisibleiE9Q9Z9 MM

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9Q9Z9_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q9Z9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: January 16, 2019
This is version 45 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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