Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 64 (31 Jul 2019)
Sequence version 1 (05 Apr 2011)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Nuclear receptor corepressor 1

Gene

Ncor1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nuclear receptor corepressor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ncor1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1349717 Ncor1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
E9Q9Y2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9Q9Y2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9Q9Y2

PeptideAtlas

More...
PeptideAtlasi
E9Q9Y2

PRoteomics IDEntifications database

More...
PRIDEi
E9Q9Y2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000018501 Expressed in 298 organ(s), highest expression level in ear vesicle

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9Q9Y2 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9Q9Y2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 68DisorderedSequence analysisAdd BLAST68
Regioni396 – 493DisorderedSequence analysisAdd BLAST98
Regioni644 – 726DisorderedSequence analysisAdd BLAST83
Regioni849 – 887DisorderedSequence analysisAdd BLAST39
Regioni906 – 1006DisorderedSequence analysisAdd BLAST101
Regioni1032 – 1120DisorderedSequence analysisAdd BLAST89
Regioni1249 – 1342DisorderedSequence analysisAdd BLAST94
Regioni1372 – 1399DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili819 – 839Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi45 – 68PolarSequence analysisAdd BLAST24
Compositional biasi437 – 482PolarSequence analysisAdd BLAST46
Compositional biasi662 – 695PolyampholyteSequence analysisAdd BLAST34
Compositional biasi870 – 886PolyampholyteSequence analysisAdd BLAST17
Compositional biasi916 – 930PolarSequence analysisAdd BLAST15
Compositional biasi960 – 988PolarSequence analysisAdd BLAST29
Compositional biasi1032 – 1074PolarSequence analysisAdd BLAST43
Compositional biasi1085 – 1102PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1290 – 1320PolarSequence analysisAdd BLAST31

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1878 Eukaryota
ENOG410YDXP LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155093

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 14 potential isoforms that are computationally mapped.Show allAlign All

E9Q9Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAARYSVPP VLQPAPHQVI TNLPEGVRLP TTRPTRPPPP LIPSSKTTVA
60 70 80 90 100
SEKPSFIMGG SISQGTPGTY LSSHNQAYPQ EAPKPSVGSI SLGLPRQQES
110 120 130 140 150
TKAAPLTYIK QEEFSPRSQN SQPEGLLVRA QHEGVVRGTA GAVQEGSITR
160 170 180 190 200
GTPASKISVE TISSLRGSIT QGTPALPQAG IPTEALVKGP VSRMPIEESS
210 220 230 240 250
PEKVREEAAS KGHVIYEGKS GHILSYDSLI CRALPRGSPH SDLKERTVLS
260 270 280 290 300
GSIMQGTPRA TAESFEDGLK YPKQIKRESP PIRAFEGAIT KGKPYDGITT
310 320 330 340 350
IKEMGRSIHE IPRQDILTQE SRKTPEVVQS TRPIIEGSIS QGTPIKFDNN
360 370 380 390 400
SGQSAIKHNV KSLITGPSKL PRGMLEIVPE NIKVVERGKY EDVKAGEPVR
410 420 430 440 450
ARHTSVVSSG PSVLRSTLHE APKAQLSPGL YDDSSARRTP VSYQNTISRG
460 470 480 490 500
SPMMNRTSDV SSSKSASHER KSTLTPTQRE SIPAKSPVPG VDPVVSHSPF
510 520 530 540 550
DPHHRSSAAG EVYRSHLPTH LDPAMPFHRA LDPAAAAYLL QRQLSPTPGY
560 570 580 590 600
PSQYQLYAME NTRQTILNDY ITSQQMQVNL RPDVTRGLSP REQPLGLPYP
610 620 630 640 650
ATRGIIDLTN MPPTILVPHA GGTSTPPMDR ITYIPGTQVT FPPRPYNAAS
660 670 680 690 700
LSPGHPTHLA AAASAERERE REREKERERE RERERERERE RIAAAPADLY
710 720 730 740 750
LRPGSEQPGR PGSHGYVRSP SPSVRTQETI LQQRPSVFQG TNGTSVITPL
760 770 780 790 800
DPTAQLRIMP LPSGGPSISQ GLPASRYNTA ADALAALVDA AASAPQMDVS
810 820 830 840 850
KTKESKHEAA RLEENLRSRS AAVSEQQQLE QKNLEVEKRS VQCVCTSSAL
860 870 880 890 900
PSGKAQPHAS VVYSEAGKDK GPPPKSRYEE ELRTRGKTTI TAANFIDVII
910 920 930 940 950
TRQIASDKDA RERGSQSSDS SSSLSSHRYE TASDAIEVIS PASSPAPPQE
960 970 980 990 1000
KPQAYQPDMV KANQAENEST RQYEGPLHHY RSQQESPSPQ QQPPLPPSSQ
1010 1020 1030 1040 1050
SEGMGQVPRT HRLITLADHI CQIITQDFAR NQVPSQPSTS TFQTSPSALS
1060 1070 1080 1090 1100
STPVRTKTSS RYSPESQSQT VLHPRPGPRV SPENLVDKSR GRPGKSPERS
1110 1120 1130 1140 1150
HIPSEPYEPI SPPQGPAVHE KQDSMLLLSQ RGVDPAEQRS DSRSPGSISY
1160 1170 1180 1190 1200
LPSFFTKLES TSPMVKSKKQ EIFRKLNSSG GGDSDMAAAQ PGTEIFNLPA
1210 1220 1230 1240 1250
VTTSGAVSSR SHSFADPASN LGLEDIIRKA LMGSFDDKVE DHGVVMSHPV
1260 1270 1280 1290 1300
GIMPGSASTS VVTSSEARRD EGEPSPHAGV CKPKLINKSN SRKSKSPIPG
1310 1320 1330 1340 1350
QSYLGTERPS SVSSVHSEGD YHRQTPGWAW EDRPSSTGST QFPYNPLTIR
1360 1370 1380 1390
MLSSTPPTQI ACAPSAITQA APHQQNRIWE REPAPLLSAQ YETLSDSDD
Length:1,399
Mass (Da):151,490
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0C1349D573CFFFDF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 14 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q60974NCOR1_MOUSE
Nuclear receptor corepressor 1
Ncor1 Rxrip13
2,453Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5RIM6Q5RIM6_MOUSE
Nuclear receptor co-repressor 1, is...
Ncor1 mCG_23374
2,454Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q2B2E9Q2B2_MOUSE
Nuclear receptor corepressor 1
Ncor1
2,386Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q8K6E9Q8K6_MOUSE
Nuclear receptor corepressor 1
Ncor1
791Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5RIN0Q5RIN0_MOUSE
Nuclear receptor corepressor 1
Ncor1
541Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6SFD2F6SFD2_MOUSE
Nuclear receptor corepressor 1
Ncor1
261Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6TWR1F6TWR1_MOUSE
Nuclear receptor corepressor 1
Ncor1
254Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6U338F6U338_MOUSE
Nuclear receptor corepressor 1
Ncor1
216Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q3UV08Q3UV08_MOUSE
Nuclear receptor corepressor 1
Ncor1
993Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8CHB6Q8CHB6_MOUSE
MKIAA1047 protein
Ncor1 mKIAA1047
1,724Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL596110 Genomic DNA No translation available.
BX248411 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000037575; ENSMUSP00000038900; ENSMUSG00000018501

UCSC genome browser

More...
UCSCi
uc007jiu.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596110 Genomic DNA No translation available.
BX248411 Genomic DNA No translation available.

3D structure databases

SMRiE9Q9Y2
ModBaseiSearch...

Proteomic databases

EPDiE9Q9Y2
jPOSTiE9Q9Y2
MaxQBiE9Q9Y2
PeptideAtlasiE9Q9Y2
PRIDEiE9Q9Y2

Genome annotation databases

EnsembliENSMUST00000037575; ENSMUSP00000038900; ENSMUSG00000018501
UCSCiuc007jiu.2 mouse

Organism-specific databases

MGIiMGI:1349717 Ncor1

Phylogenomic databases

eggNOGiKOG1878 Eukaryota
ENOG410YDXP LUCA
GeneTreeiENSGT00940000155093

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ncor1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000018501 Expressed in 298 organ(s), highest expression level in ear vesicle
ExpressionAtlasiE9Q9Y2 baseline and differential

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9Q9Y2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q9Y2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 31, 2019
This is version 64 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again