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Entry version 65 (08 May 2019)
Sequence version 2 (03 Oct 2012)
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Protein

PDZ domain-containing protein 7

Gene

Pdzd7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In cochlear developing hair cells, essential in organizing the USH2 complex at stereocilia ankle links (PubMed:24334608). Blocks inhibition of adenylate cyclase activity mediated by ADGRV1 (PubMed:24962568).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PDZ domain-containing protein 7Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pdzd7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3608325 Pdzd7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Cilium, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mutant mice exhibit congenital profound deafness and normal vestibular function. They show disorganized stereocilia bundles with a reduction in mechanotransduction currents and sensitivity in cochlear outer cells (PubMed:24334608). Knockout mice have normal vision function from rod and cone photoreceptors (PubMed:24334608).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004457381 – 1021PDZ domain-containing protein 7Add BLAST1021

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
E9Q9W7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 1 is expressed in developing and adult cochlea but not retina (PubMed:24334608). Isoform 2 is expressed in developing and adult cochlea and retina (PubMed:24334608). Isoform 3 is expressed in adult cochlea and retina (PubMed:24334608). Isoform 4 is expressed in retina and developing cochlea but not adult cochlea (PubMed:24334608). Isoform 5 is expressed in adult cochlea but not in developing cochlea or retina (PubMed:24334608).1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

In cochlea hair cells, only isoforms 1, 2 and 4 are expressed at P5. At P24, isoforms 1, 2, 3 and 5 are expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000074818 Expressed in 18 organ(s), highest expression level in skeletal muscle tissue

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimerizes (via PDZ2 domain) (PubMed:25406310). Component of USH2 complex, composed of ADGRV1, PDZD7, USH2A and WHRN (PubMed:25406310). Interacts (via PDZ domains) with WHRN; the interaction is direct (PubMed:25406310). Interacts with USH1G (By similarity). Interacts with ADGRV1 (via the cytoplasmic region) (PubMed:24962568, PubMed:23055499). Interacts with USH2A (via the cytoplasmic region) (PubMed:23055499). Interacts with MYO7A (via MyTH4-FERM domains) (PubMed:27525485).By similarity4 Publications

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000119002

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9Q9W7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini86 – 156PDZ 1PROSITE-ProRule annotationAdd BLAST71
Domaini210 – 279PDZ 2PROSITE-ProRule annotationAdd BLAST70
Domaini858 – 930PDZ 3PROSITE-ProRule annotationAdd BLAST73

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410ITA9 Eukaryota
ENOG411197M LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183002

KEGG Orthology (KO)

More...
KOi
K21882

Identification of Orthologs from Complete Genome Data

More...
OMAi
RSACTPP

Database of Orthologous Groups

More...
OrthoDBi
168224at2759

TreeFam database of animal gene trees

More...
TreeFami
TF325033

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00595 PDZ, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: E9Q9W7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MARGFTVGFD PLGLGELSSG SLSSVSSRGH LGSDSGSTAT RYLLRKQQRL
60 70 80 90 100
LNGPSRGIRA SSPMGRVILI NSPIEANSDE SDIIHAVRVE KSPSGRLGFS
110 120 130 140 150
VRGGSEHGLG IFVSKVEEGS SAERAGLCVG DKITEVNGLS LESTTMGSAV
160 170 180 190 200
RLLTSSSCLH MMVRRMGRVP GIKFSKEKTT WVDVVNRRLV VEKCSSTPSD
210 220 230 240 250
RSSEDGVRRI VHLYTTSDDF CLGFNIRGGK EFGLGIYVSK VDHGGLAEEN
260 270 280 290 300
GIKVGDQVLA ANGVRFDDIS HSQAVEVLKG QTHIMLTIKE TGRYPAYKEM
310 320 330 340 350
VSEYCWLDRL SNGVLQQLSP ASESSSSVSS YASSAPCSSG SLPSDRMDVC
360 370 380 390 400
LGPEEPTSHG PGWGRADTAM QTEPDLDSRV ETWCSVRPTV ILRDTAIRSD
410 420 430 440 450
GPSSTRHLDS ALSESPKTAL LLALSRPRTP ITRSQSHLTL WEEKKQRKKE
460 470 480 490 500
KSGSSGEKGA LQRSKTLMNL FFKGGRQGRP AGDGHREAWT LDSRSPTKVR
510 520 530 540 550
PRLDLEKAGS VGPVQKFVTW RLRRDRERGR ALLSARSGSP SGQAPTVNEQ
560 570 580 590 600
VQAWESRRPL IQDLARRLLT DDEVLAVTRH CSRYVHEGGV EDLVRPLLAI
610 620 630 640 650
LDRPTKLLLL RDIRSVVAPT DLGRFDSMVM PVELEAFEAL KSRAVGPSAL
660 670 680 690 700
RPTRQDTPPK RHLITPVPDS RGGFYLLPVN SSEDEDGEIR EKLGVLKVSL
710 720 730 740 750
GASAPHHKGI PPLQDVPVDA FSLRRGACAP PPQPPPVAPR PPRPNWLLTE
760 770 780 790 800
PLSREDTQQN QSQTPAQSCS RSRSRSRSRS HSRGQGKSPG RRRSPSPAPI
810 820 830 840 850
ATAATANGRY HRPRKARPLL PRLLDGQVAK VGARQGPLEN GRIAEEAVGN
860 870 880 890 900
VSTGALRTIT LSKMKQSLGI SISGGIESKV QPMVKIEKIF PGGAAFLCGD
910 920 930 940 950
LQAGFELVAV DGESLEQVTH QRAVDTIRRA YRNKAREPME LVVRVPGPGL
960 970 980 990 1000
LPLASDLRVV KDQSLAPDCP SALGPVDDAR ILTQLPPPEA RQLQQSLSSA
1010 1020
LKVPQSIPKL SPILKDPHDP S
Note: Expressed in developing and adult cochlea but not retina.1 Publication
Length:1,021
Mass (Da):110,694
Last modified:October 3, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i325866A1EA64DAF6
GO
Isoform 21 Publication (identifier: E9Q9W7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     508-553: AGSVGPVQKF...APTVNEQVQA → VPRMLVSHGS...GLCRSLSPGD
     554-1021: Missing.

Note: Expressed in developing and adult cochlea and retina.1 Publication
Show »
Length:553
Mass (Da):59,860
Checksum:i1C6961310FF58CD2
GO
Isoform 31 Publication (identifier: E9Q9W7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     442-476: EEKKQRKKEKSGSSGEKGALQRSKTLMNLFFKGGR → ALPGAPSYLQRRRNNGRRRSRDLLGRRGPCSAPRR
     477-1021: Missing.

Note: Expressed in adult cochlea and retina.1 Publication
Show »
Length:476
Mass (Da):51,387
Checksum:iB878BCDB80E1ADC1
GO
Isoform 41 Publication (identifier: E9Q9W7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     290-1021: Missing.

Note: Expressed in retina and developing cochlea but not adult cochlea.1 Publication
Show »
Length:289
Mass (Da):30,892
Checksum:iD223920E04CFE377
GO
Isoform 51 Publication (identifier: E9Q9W7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     386-409: VRPTVILRDTAIRSDGPSSTRHLD → SPPRLLSFWPSADPELPSLDPRAT
     410-1021: Missing.

Note: Expressed in adult cochlea but not in developing cochlea or retina.1 Publication
Show »
Length:409
Mass (Da):43,860
Checksum:i913809507698E4E8
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_059952290 – 1021Missing in isoform 4. Add BLAST732
Alternative sequenceiVSP_059953386 – 409VRPTV…TRHLD → SPPRLLSFWPSADPELPSLD PRAT in isoform 5. Add BLAST24
Alternative sequenceiVSP_059954410 – 1021Missing in isoform 5. Add BLAST612
Alternative sequenceiVSP_059955442 – 476EEKKQ…FKGGR → ALPGAPSYLQRRRNNGRRRS RDLLGRRGPCSAPRR in isoform 3. Add BLAST35
Alternative sequenceiVSP_059956477 – 1021Missing in isoform 3. Add BLAST545
Alternative sequenceiVSP_059957508 – 553AGSVG…EQVQA → VPRMLVSHGSQPSSLARPLS FHDSSFPLCFLKRGVWGLCR SLSPGD in isoform 2. Add BLAST46
Alternative sequenceiVSP_059958554 – 1021Missing in isoform 2. Add BLAST468

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
KF041446 mRNA Translation: AHV90413.1
KF041447 mRNA Translation: AHV90414.1
KF041449 mRNA Translation: AHV90416.1
KF041450 mRNA Translation: AHV90417.1
KF041451 mRNA Translation: AHV90418.1
AC132957 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS57145.1 [E9Q9W7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001182194.1, NM_001195265.1 [E9Q9W7-1]
XP_006526599.1, XM_006526536.1 [E9Q9W7-1]
XP_006526600.1, XM_006526537.3 [E9Q9W7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000145391; ENSMUSP00000119002; ENSMUSG00000074818 [E9Q9W7-1]
ENSMUST00000169459; ENSMUSP00000133273; ENSMUSG00000074818 [E9Q9W7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100503041

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:100503041

UCSC genome browser

More...
UCSCi
uc012bmk.1 mouse [E9Q9W7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KF041446 mRNA Translation: AHV90413.1
KF041447 mRNA Translation: AHV90414.1
KF041449 mRNA Translation: AHV90416.1
KF041450 mRNA Translation: AHV90417.1
KF041451 mRNA Translation: AHV90418.1
AC132957 Genomic DNA No translation available.
CCDSiCCDS57145.1 [E9Q9W7-1]
RefSeqiNP_001182194.1, NM_001195265.1 [E9Q9W7-1]
XP_006526599.1, XM_006526536.1 [E9Q9W7-1]
XP_006526600.1, XM_006526537.3 [E9Q9W7-1]

3D structure databases

SMRiE9Q9W7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000119002

Proteomic databases

PRIDEiE9Q9W7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000145391; ENSMUSP00000119002; ENSMUSG00000074818 [E9Q9W7-1]
ENSMUST00000169459; ENSMUSP00000133273; ENSMUSG00000074818 [E9Q9W7-1]
GeneIDi100503041
KEGGimmu:100503041
UCSCiuc012bmk.1 mouse [E9Q9W7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79955
MGIiMGI:3608325 Pdzd7

Phylogenomic databases

eggNOGiENOG410ITA9 Eukaryota
ENOG411197M LUCA
GeneTreeiENSGT00950000183002
KOiK21882
OMAiRSACTPP
OrthoDBi168224at2759
TreeFamiTF325033

Miscellaneous databases

Protein Ontology

More...
PROi
PR:E9Q9W7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000074818 Expressed in 18 organ(s), highest expression level in skeletal muscle tissue

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF00595 PDZ, 3 hits
SMARTiView protein in SMART
SM00228 PDZ, 3 hits
SUPFAMiSSF50156 SSF50156, 3 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPDZD7_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q9W7
Secondary accession number(s): E9Q9U9
, X4YT42, X4YT46, X4YZM3, X4ZGA7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 5, 2018
Last sequence update: October 3, 2012
Last modified: May 8, 2019
This is version 65 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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