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UniProtKB - E9Q8T7 (DYH1_MOUSE)

Protein

Dynein heavy chain 1, axonemal

Gene

Dnah1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Force generating protein of cilia required for sperm flagellum motility (PubMed:11371505). Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme (By similarity).By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi1566 – 1573ATPSequence analysis8
Nucleotide bindingi1847 – 1854ATPSequence analysis8
Nucleotide bindingi2212 – 2219ATPSequence analysis8
Nucleotide bindingi2571 – 2578ATPSequence analysis8

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ATP-dependent microtubule motor activity, minus-end-directed Source: GO_Central
  • dynein intermediate chain binding Source: GO_Central
  • dynein light chain binding Source: GO_Central
  • dynein light intermediate chain binding Source: GO_Central
  • microtubule motor activity Source: MGI
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionMotor protein
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Dynein heavy chain 1, axonemal
Alternative name(s):
Axonemal beta dynein heavy chain 1
Ciliary dynein heavy chain 1
mDHC71 Publication
Gene namesi
Name:Dnah1Imported
Synonyms:Dhc7, Dnahc1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:107721 Dnah1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton, Dynein, Flagellum, Microtubule

Pathology & Biotechi

Disruption phenotypei

Mice are viable and show no malformations; however, homozygous males are infertile, due to inability of spermatozoa to move from the uterus into the oviduct. Spermatozoa show decreased motility. In addition, tracheal beating frequency is reduced.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004424301 – 4250Dynein heavy chain 1, axonemalAdd BLAST4250

Proteomic databases

MaxQBiE9Q8T7
PaxDbiE9Q8T7
PRIDEiE9Q8T7

PTM databases

iPTMnetiE9Q8T7
PhosphoSitePlusiE9Q8T7

Expressioni

Gene expression databases

BgeeiENSMUSG00000019027 Expressed in 115 organ(s), highest expression level in cerebellum
GenevisibleiE9Q8T7 MM

Interactioni

Subunit structurei

Consists of at least two heavy chains and a number of intermediate and light chains.By similarity

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043281

Structurei

3D structure databases

SMRiE9Q8T7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 1527StemBy similarityAdd BLAST1527
Regioni1528 – 1749AAA 1By similarityAdd BLAST222
Regioni1809 – 2042AAA 2By similarityAdd BLAST234
Regioni2174 – 2434AAA 3By similarityAdd BLAST261
Regioni2532 – 2784AAA 4By similarityAdd BLAST253
Regioni2799 – 3097StalkBy similarityAdd BLAST299
Regioni3182 – 3412AAA 5By similarityAdd BLAST231
Regioni3625 – 3844AAA 6By similarityAdd BLAST220

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili3045 – 3128Sequence analysisAdd BLAST84

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi1566 – 1573GPAGTGKT motif8
Motifi1616 – 1622CFDEFNR motif7

Sequence similaritiesi

Belongs to the dynein heavy chain family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00910000144015
HOVERGENiHBG104858
InParanoidiE9Q8T7
KOiK10408
OMAiTEWRDDV
OrthoDBiEOG091G00FO
PhylomeDBiE9Q8T7
TreeFamiTF316836

Family and domain databases

InterProiView protein in InterPro
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR026975 DNAH1
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PTHR10676:SF358 PTHR10676:SF358, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SUPFAMiSSF52540 SSF52540, 4 hits

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: E9Q8T7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEECNKEGPS SSSQGPGYCP VKVPESHDLE KILQESNYHP ERNPLNPDPK 
        60         70         80         90        100
TPPLPLTDLR QPRKSPLTGT DKKYPLMKQR GFYSDILSPG TLDKLGNVCC 
       110        120        130        140        150
GPYMSQNLIR QADLDKFTPK VDSFVIPEDF QERVEQQIIG ATTRLLTQTD 
       160        170        180        190        200
FPLQSYEPKV QVPFQVLPGQ CPRKIEIERR KQQYLRLDIE QLLTSEGIDS 
       210        220        230        240        250
NKLMPRHPDL QHPQTIEQGR DPLFPIYLPL KVFDNEEFDC RTPTEWLNMG 
       260        270        280        290        300
LEPGSQNRKP VPGKALLPTD DDLGHEDPKN QELDYRWCEV GVLDYDEEKK 
       310        320        330        340        350
LYLVQKTDKR GLVRDEMGMP ILNGGITPAG RPPLLATQYW VPRIQLLFCA 
       360        370        380        390        400
EDPRVFTQRV VQANALRKYT EALLMYNLYV DCMPTEGRRV INEQSLSKIK 
       410        420        430        440        450
QWALSTPRMR KGQSVLEHLS CLAREVNLDY ERSMNKINFD QIVSSNPETF 
       460        470        480        490        500
SYVTLPEKEE EKVPNQGLVS VPEYPFREQK EDFTFVSLLT RPEVITALSK 
       510        520        530        540        550
VRAECNKVTS MSLFHSSLSK YSRLEEFEQI QSQTFSQVQM FLKDSWISTL 
       560        570        580        590        600
KVAMRGSLRD MSKGWYNLYE TNWEVYLMSK LRKLMELIKY MLQDTLRFLV 
       610        620        630        640        650
QDSLGSFTQF IGDACCSVLE CVDDMDWGED LVNSPYKPRK NPLFIVDLVL 
       660        670        680        690        700
DNSGVHYSTP LEHFEMILLN LFDKGILATH AVPQLEKLVM EDIFISGDPL 
       710        720        730        740        750
LESVGLHEPL VEELRANITN AMHKAMMPLQ AYAKEYRKYL ELNNNDISTF 
       760        770        780        790        800
LKTYQTQCPS AEEVREVVIT HLKEKEILDN SLPSSIIIGP FYINVDNVKQ 
       810        820        830        840        850
SLSKKRKALA TSMLDILAKN LHKEVDSICE EFRSISRKIY EKPNSIEELA 
       860        870        880        890        900
ELRDWMKGIP EKLVFLEERI VKVMSDYEVM DEFFYNLTTD DFNDKWAANN 
       910        920        930        940        950
WPSKILGQID MVRQQHVEDE EKFRKIQLMD QNNFQEKLEG LQLVVAGFSI 
       960        970        980        990       1000
HVEIARAHEI ANEVRRVKKQ LKDCQQLAML YNNRERIFGL PITNYDKLSR 
      1010       1020       1030       1040       1050
MVKEFQPYLD LWTTASDWLR WSESWMNDPL SAIDAEQLEK NVIESFKTMH 
      1060       1070       1080       1090       1100
KCVKQFKDIP ACQEVALDIR TRIEEFKPYI PLIQGLRNPG MRNRHWEVLS 
      1110       1120       1130       1140       1150
NEININVRPK ANLTFARCLE MNLQDHIESI SKVAEVAGKE YAIEQALDKM 
      1160       1170       1180       1190       1200
EKEWSSILFN VLPYKETDTY ILKSPDEASQ LLDDHIVMTQ SMSFSPYKKP 
      1210       1220       1230       1240       1250
FEQRINSWET KLKLTQEVLE EWLNCQRAWL YLEPIFSSED ITRQLPVESK 
      1260       1270       1280       1290       1300
RYQTMERIWR KIMKNAYENR EVINVCSDQR LLDSLRDCNK LLDLVQKGLS 
      1310       1320       1330       1340       1350
EYLETKRTAF PRFYFLSDDE LLEILSQTKD PTAVQPHLRK CFENIARLLF 
      1360       1370       1380       1390       1400
QEDLEITHMY SAEGEEVKLS FSIYPSSNVE DWLLEVERSM KASVHDIIEM 
      1410       1420       1430       1440       1450
AIKAYPTMLR TEWVLNWPGQ VTIAGCQTYW TMEVAEALEA GNISSKLFPQ 
      1460       1470       1480       1490       1500
LSKQLSDLVA LVRGKLSRMQ RMVLSALIVI EVHAKDVVSK LIDENVVSVH 
      1510       1520       1530       1540       1550
DFEWISQLRY YWTKDDLYIR AVNAEFIYGY EYLGNSGRLV ITPLTDRCYL 
      1560       1570       1580       1590       1600
TLTGALHLKF GGAPAGPAGT GKTETTKDLG KALAIQTVVF NCSDQLDFMA 
      1610       1620       1630       1640       1650
MGKFFKGLAS AGAWACFDEF NRIDIEVLSV VAQQITTIQK AQQQRVERFM 
      1660       1670       1680       1690       1700
FEGVEIPLVP SCAVFITMNP GYAGRTELPD NLKALFRPVA MMVPDYAMIA 
      1710       1720       1730       1740       1750
EISLYSFGFN EANVLAKKIT TTFKLSSEQL SSQDHYDFGM RAVKTVISAA 
      1760       1770       1780       1790       1800
GNLKRENPTM NEELICLRAI RDVNVPKFLQ EDLKLFSGIV SDLFPTIKEE 
      1810       1820       1830       1840       1850
ETDYGILDQA IRRSCEKNNL KDVEGFLIKC IQLYETTVVR HGLMLVGPTG 
      1860       1870       1880       1890       1900
SGKSNCYRVL AAAMTLLKGK PSISGGVYEA VNYYVLNPKS ITMGQLYGEF 
      1910       1920       1930       1940       1950
DLLTHEWTDG IFSSLIRAGA IASDTNKKWY MFDGPVDAVW IENMNTVLDD 
      1960       1970       1980       1990       2000
NKKLCLSSGE IIKLTEAMTM MFEVQDLAVA SPATVSRCGM VYLEPSILGL 
      2010       2020       2030       2040       2050
MPFVECWLKR LPAIIKPYEE QFKSLFTKYL ENSINFVRNT VKEVIASTNS 
      2060       2070       2080       2090       2100
NLTMSLLKLL DCFFRPFLPR EGLKKIPSEK LSHIPELIEP WFIFSLVWSV 
      2110       2120       2130       2140       2150
GATGDHTSRI SFSQWLRLKM RLEQVKLGFP EDGLVYDYRL DDAGISSTED 
      2160       2170       2180       2190       2200
DDEEEDENKQ VSWVKWMDYS APFTMMPDTN YCNIIVPTMD TVQMSYLLGM 
      2210       2220       2230       2240       2250
LLTNHKPVLC IGPTGTGKTL TVSNKLLKYL PLEYISHFLT FSARTSANQT 
      2260       2270       2280       2290       2300
QDLIDSKLDK RRKGVFGPPL GRNFIFFIDD LNMPALETYG AQPPIELLRQ 
      2310       2320       2330       2340       2350
WMDHGGWYDR KVIGAFKNLV DINFVCAMGP PGGGRNAITP RLTRHFNYLS 
      2360       2370       2380       2390       2400
FIEMDEVSKK RIFSIILECW MDGLLGEKSY REPVPGAPNI DDLTEPLVDA 
      2410       2420       2430       2440       2450
TINVYGIITS QLLPTPAKSH YTFNLRDLSK VFQGMLMAEP SKVEDKVQLL 
      2460       2470       2480       2490       2500
RLWYHENCRV FRDRLVNEED RSWFDELLEA QMEEFGVAFN KVCPFQPILY 
      2510       2520       2530       2540       2550
GDFMSPGSDV KSYELITSES KMMQVIEEYM EDYNQINTAK LRLVLFVDAM 
      2560       2570       2580       2590       2600
SHICRISRTL RQALGNALLL GVGGSGRSSL TRLASHMAEY ECFQIELSKN 
      2610       2620       2630       2640       2650
YGMSEWREDV KKVLLKAGLQ NLPITFLFSD TQIKNESFLE DINNVLNSGD 
      2660       2670       2680       2690       2700
IPNIYSADEQ DQIINTMRPY IQEQGLQPTK ANLMAAYTGR VRSNIHMVLC 
      2710       2720       2730       2740       2750
MSPIGEVFRA RLRQFPSLVN CCTIDWFNEW PAEALKSVAT TFLSEIPELE 
      2760       2770       2780       2790       2800
CSEEVIQGLI QVCVFIHQSV ASKCVEYLAE LARHNYVTPK SYLELLNIFS 
      2810       2820       2830       2840       2850
ILIGQKKMEL KTAKNRMKSG LDKLLRTSED VAKMQEELEI MRPLLEEAAK 
      2860       2870       2880       2890       2900
DTMLTMEQIK VDTAIAEETR KSVQAEEIKA NEKANKAQAI ADDAQKDLDE 
      2910       2920       2930       2940       2950
ALPALDAALA SLRNLNKNDV TEVRAMQRPP PGVKLVIEAV CIMKGIKPKK 
      2960       2970       2980       2990       3000
VPGEKPGSKV DDYWEPGKGL LQDPGRFLES LFKFDKDNIG EAVIKAIQPY 
      3010       3020       3030       3040       3050
IDNEEFQPAA IAKVSKACTS ICQWVRAMHK YHFVAKAVEP KRQALREAQD 
      3060       3070       3080       3090       3100
DLEVTQRILE EAKHHLHEVE DGIATMQAKY RECVAKKEEL EMKCEQCEQR 
      3110       3120       3130       3140       3150
LGRADKLING LADEKVRWQE TVENLENMLD NIFGDVLVAA GFVAYLGPFT 
      3160       3170       3180       3190       3200
GQYRTTLYEY WVNQLTVHHV PHTSKPTLIT TLGNPVKIRS WQIAGLPNDT 
      3210       3220       3230       3240       3250
LSVENGVINQ FSQRWTHFID PQGQANKWIK NMERESGLDV FKLSDRDFLR 
      3260       3270       3280       3290       3300
SMENAIRFGK PCLLENVGEE LDPALEPVLL KQTYKQQGNI VLKLGDTVIP 
      3310       3320       3330       3340       3350
YHEDFRMYIT TKLPNPHYSP EISTKLTLIN FTLSPSGLED QLLGQVVAEE 
      3360       3370       3380       3390       3400
RPDLEEAKNQ LIVSNAKMRQ ELKDIEDQIL YRLSSSEGNP VDDMELIKVL 
      3410       3420       3430       3440       3450
EASKMKAAEI QAKVRIAEQT EKDIDLTRME YIPVAVRTQI LFFCVSDLAN 
      3460       3470       3480       3490       3500
VDPMYQYSLE WFLNIFLSGI ANSERADNLK KRIVNINRYL TFSLYSNVCR 
      3510       3520       3530       3540       3550
SLFEKHKLMF AFLLCVRIMM NEGKINQAEW RYLLSGGSIQ TMFENPAPQW 
      3560       3570       3580       3590       3600
LSDRAWRDIL ALSNLPTFAT FSNDFVMYLS EFQAIFDSAE PHRELLPGIW 
      3610       3620       3630       3640       3650
NAYLDEFQKL LILRCLRGDK VTNAMQDFVA THLEPRFIEP QTANLSAVFK 
      3660       3670       3680       3690       3700
ESNSTTPLIF VLSPGTDPAA DLYKFAEEMK FSKKFSAISL GQGQGPRAEA 
      3710       3720       3730       3740       3750
MMRNSIERGK WVFFQNCHLA PSWMPALERL IEHINPDKVH RDFRLWLTSL 
      3760       3770       3780       3790       3800
PSNKFPVSIL QNGSKMTIEP PRGVKANLLK SYNSLSDDFL HSCQKVVEFK 
      3810       3820       3830       3840       3850
SLLLSLCLFH GNALERRKFG PLGFNIPYEF TDGDLRICIS QLKMFLDEYE 
      3860       3870       3880       3890       3900
DIPYKVLKYT AGEINYGGRV TDDWDRRCVM NILEDFYNPA VLSSEHSYSN 
      3910       3920       3930       3940       3950
SGIYHQIPPT YDLNGYLSYI KSLPLNDMPE IFGLHDNANI TFAQNETFAL 
      3960       3970       3980       3990       4000
FNAILQLQPK SSSMGGQSRE ELVEDVAENI LLQVPGPIEL QEVTKKFPVL 
      4010       4020       4030       4040       4050
YEESMNTVLV QEVIRYNKLL EVITQTLSDM LKAIKGLVVM SLELELMSIS 
      4060       4070       4080       4090       4100
LYNNTVPELW KSKAYPSLKP LASWIMDLLL RLDFMHSWIN DGIPPVFWIS 
      4110       4120       4130       4140       4150
GFFFPQAFLT GTLQNFARKF VISIDTITFD FKVLPEASSE IKERPQTGCY 
      4160       4170       4180       4190       4200
IHGLFLEGAR WDSMNFQLAE SRPKELYTEM AVIWLLPEAN RKVQNQDFYL 
      4210       4220       4230       4240       4250
CPIYKTLTRA GTLSTTGHST NYVIAVEIPS NQPQRHWIKR GVALICALDY
Length:4,250
Mass (Da):487,070
Last modified:April 5, 2011 - v1
Checksum:i27CA12B77EC9E3F9
GO
Isoform 2 (identifier: E9Q8T7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     468-486: LVSVPEYPFREQKEDFTFV → ESHWTLAAHLASSPHLRLS
     487-4250: Missing.

Show »
Length:486
Mass (Da):55,763
Checksum:i13F2DE53D81572CC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti839I → L in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti854D → V in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti1111A → G in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti1136V → M in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti1302Y → S in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti1389S → I in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti1406P → L in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti1427Q → R in CAB06069 (PubMed:9373155).Curated1
Sequence conflicti2025 – 2046LFTKY…KEVIA → SLPSTWRIPSTCSEHSEGSD C in CAB06069 (PubMed:9373155).CuratedAdd BLAST22
Sequence conflicti2052L → V in CAB06069 (PubMed:9373155).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_059235468 – 486LVSVP…DFTFV → ESHWTLAAHLASSPHLRLS in isoform 2. Add BLAST19
Alternative sequenceiVSP_059236487 – 4250Missing in isoform 2. Add BLAST3764

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053204 mRNA Translation: BAC35309.1
AC108416 Genomic DNA No translation available.
CH466573 Genomic DNA Translation: EDL24805.1
BC023155 mRNA Translation: AAH23155.1
Z83815 mRNA Translation: CAB06069.2
CCDSiCCDS49436.1 [E9Q8T7-1]
RefSeqiNP_001028840.1, NM_001033668.1 [E9Q8T7-1]
XP_017171287.1, XM_017315798.1 [E9Q8T7-1]
XP_017171288.1, XM_017315799.1 [E9Q8T7-1]
UniGeneiMm.101811

Genome annotation databases

EnsembliENSMUST00000048603; ENSMUSP00000043281; ENSMUSG00000019027 [E9Q8T7-1]
GeneIDi110084
KEGGimmu:110084
UCSCiuc007sxk.2 mouse [E9Q8T7-1]
uc007sxl.1 mouse

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK053204 mRNA Translation: BAC35309.1
AC108416 Genomic DNA No translation available.
CH466573 Genomic DNA Translation: EDL24805.1
BC023155 mRNA Translation: AAH23155.1
Z83815 mRNA Translation: CAB06069.2
CCDSiCCDS49436.1 [E9Q8T7-1]
RefSeqiNP_001028840.1, NM_001033668.1 [E9Q8T7-1]
XP_017171287.1, XM_017315798.1 [E9Q8T7-1]
XP_017171288.1, XM_017315799.1 [E9Q8T7-1]
UniGeneiMm.101811

3D structure databases

SMRiE9Q8T7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043281

PTM databases

iPTMnetiE9Q8T7
PhosphoSitePlusiE9Q8T7

Proteomic databases

MaxQBiE9Q8T7
PaxDbiE9Q8T7
PRIDEiE9Q8T7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000048603; ENSMUSP00000043281; ENSMUSG00000019027 [E9Q8T7-1]
GeneIDi110084
KEGGimmu:110084
UCSCiuc007sxk.2 mouse [E9Q8T7-1]
uc007sxl.1 mouse

Organism-specific databases

CTDi25981
MGIiMGI:107721 Dnah1

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00910000144015
HOVERGENiHBG104858
InParanoidiE9Q8T7
KOiK10408
OMAiTEWRDDV
OrthoDBiEOG091G00FO
PhylomeDBiE9Q8T7
TreeFamiTF316836

Miscellaneous databases

PROiPR:E9Q8T7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019027 Expressed in 115 organ(s), highest expression level in cerebellum
GenevisibleiE9Q8T7 MM

Family and domain databases

InterProiView protein in InterPro
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR026975 DNAH1
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PTHR10676:SF358 PTHR10676:SF358, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SUPFAMiSSF52540 SSF52540, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiDYH1_MOUSE
AccessioniPrimary (citable) accession number: E9Q8T7
Secondary accession number(s): O08828, Q8R584
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2017
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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