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Entry version 66 (07 Oct 2020)
Sequence version 1 (05 Apr 2011)
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Protein
Submitted name:

Transforming acidic coiled-coil-containing protein 2

Gene

Tacc2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transforming acidic coiled-coil-containing protein 2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tacc2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1928899, Tacc2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9Q8T1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9Q8T1

PeptideAtlas

More...
PeptideAtlasi
E9Q8T1

PRoteomics IDEntifications database

More...
PRIDEi
E9Q8T1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9Q8T1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9Q8T1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000030852, Expressed in hindlimb stylopod muscle and 303 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9Q8T1, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9Q8T1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2673 – 2873TACC_CInterPro annotationAdd BLAST201

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 273DisorderedSequence analysisAdd BLAST273
Regioni291 – 364DisorderedSequence analysisAdd BLAST74
Regioni395 – 603DisorderedSequence analysisAdd BLAST209
Regioni618 – 640DisorderedSequence analysisAdd BLAST23
Regioni712 – 761DisorderedSequence analysisAdd BLAST50
Regioni775 – 951DisorderedSequence analysisAdd BLAST177
Regioni964 – 1222DisorderedSequence analysisAdd BLAST259
Regioni1416 – 1438DisorderedSequence analysisAdd BLAST23
Regioni1450 – 1481DisorderedSequence analysisAdd BLAST32
Regioni1500 – 1562DisorderedSequence analysisAdd BLAST63
Regioni1693 – 1930DisorderedSequence analysisAdd BLAST238
Regioni1950 – 2133DisorderedSequence analysisAdd BLAST184
Regioni2166 – 2320DisorderedSequence analysisAdd BLAST155
Regioni2339 – 2369DisorderedSequence analysisAdd BLAST31
Regioni2399 – 2430DisorderedSequence analysisAdd BLAST32
Regioni2485 – 2509DisorderedSequence analysisAdd BLAST25

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2606 – 2626Sequence analysisAdd BLAST21
Coiled coili2682 – 2723Sequence analysisAdd BLAST42
Coiled coili2742 – 2783Sequence analysisAdd BLAST42
Coiled coili2791 – 2836Sequence analysisAdd BLAST46
Coiled coili2841 – 2875Sequence analysisAdd BLAST35

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 62PolarSequence analysisAdd BLAST62
Compositional biasi122 – 163PolarSequence analysisAdd BLAST42
Compositional biasi212 – 227PolyampholyteSequence analysisAdd BLAST16
Compositional biasi232 – 250PolarSequence analysisAdd BLAST19
Compositional biasi297 – 317PolarSequence analysisAdd BLAST21
Compositional biasi334 – 364PolarSequence analysisAdd BLAST31
Compositional biasi395 – 436PolarSequence analysisAdd BLAST42
Compositional biasi456 – 508PolarSequence analysisAdd BLAST53
Compositional biasi512 – 528PolyampholyteSequence analysisAdd BLAST17
Compositional biasi541 – 570PolyampholyteSequence analysisAdd BLAST30
Compositional biasi571 – 588PolarSequence analysisAdd BLAST18
Compositional biasi806 – 835PolarSequence analysisAdd BLAST30
Compositional biasi848 – 876PolarSequence analysisAdd BLAST29
Compositional biasi890 – 920PolarSequence analysisAdd BLAST31
Compositional biasi932 – 951PolarSequence analysisAdd BLAST20
Compositional biasi1106 – 1124PolarSequence analysisAdd BLAST19
Compositional biasi1147 – 1161PolarSequence analysisAdd BLAST15
Compositional biasi1466 – 1481PolarSequence analysisAdd BLAST16
Compositional biasi1515 – 1529PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1530 – 1562PolarSequence analysisAdd BLAST33
Compositional biasi1698 – 1713PolarSequence analysisAdd BLAST16
Compositional biasi1730 – 1745PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1780 – 1800PolarSequence analysisAdd BLAST21
Compositional biasi1856 – 1889Pro-richSequence analysisAdd BLAST34
Compositional biasi1967 – 1991PolarSequence analysisAdd BLAST25
Compositional biasi1999 – 2024PolarSequence analysisAdd BLAST26
Compositional biasi2042 – 2056PolarSequence analysisAdd BLAST15
Compositional biasi2242 – 2267PolarSequence analysisAdd BLAST26
Compositional biasi2278 – 2297PolarSequence analysisAdd BLAST20
Compositional biasi2401 – 2423PolarSequence analysisAdd BLAST23
Compositional biasi2491 – 2509PolarSequence analysisAdd BLAST19

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TACC family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157052

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000545_0_0_1

Database of Orthologous Groups

More...
OrthoDBi
669540at2759

TreeFam database of animal gene trees

More...
TreeFami
TF333149

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039915, TACC
IPR007707, TACC_C

The PANTHER Classification System

More...
PANTHERi
PTHR13924, PTHR13924, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05010, TACC_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 13 potential isoforms that are computationally mapped.Show allAlign All

E9Q8T1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNENSTSDH QRTSSVQSPR SLQPPGKSQS LQKQQGDLPG SCAGSTGLGG
60 70 80 90 100
SCSASESVAS LDPCTVSPEV AEQGEHPQEA RGPEGSPLPR SSLPWEQPCP
110 120 130 140 150
SASMPFTEGP SEGCLASSEA EAPEDSTLTN HLRMEPSPNI PGNILPTSTP
160 170 180 190 200
EVDGPTQHSM AARTPSAEGD KELKEEGPNS SSNRTGQLPG ISLVPLQEPR
210 220 230 240 250
TELLSGEGTG PRDFEFQRKE DMDDCPSPES ATKAPAATQP GMQNSADLES
260 270 280 290 300
PPKLETMVPQ DSVLRSSDRE RDGVEVLPTC SAKNLEFLEG CHPSKSNSRA
310 320 330 340 350
IPGSGTSTAS QESCQQKVEM HLPYAELPSG PPGLTTAPAN SGSWKETLDT
360 370 380 390 400
SDAQRQPQTG TSGTELQQVV CVAAASQLNG SFLLSAEAPL FTRTEETSSS
410 420 430 440 450
ASSPTAHAAA WNSVASEEST ETVSETKMSV SADLAATEQM DTGVAERKPT
460 470 480 490 500
SDLRKTQEQP EGSLQQVPAP FLQGQNDTVQ QGLLLPTFSH GISNESSVEP
510 520 530 540 550
TDGPKAPKNT QNRVVAREES RSHGDNLEGQ QEATRALAGA EPGNHDEEKS
560 570 580 590 600
QAFHSKPHLE TKKGEVSKAH SNTENKIVPS SDSTQPLRQE VAGHRDGSHS
610 620 630 640 650
GSAEVVGQVV AESHVTDTAT SLHKLHEEDP ILSSASDGTG EHFLPQEAIW
660 670 680 690 700
ESSRSQTKSP VMLQDRGGLE AIESLPALES EKGDFLPATA AEEVPKAGEM
710 720 730 740 750
EDILEVKKSH SPFHPPFSCD GEGLLMSPGQ PCGVEKVEPG QEVHADASSP
760 770 780 790 800
RNGKDSTIGH GLAVLSLEQD CQRKLSCPED SLPPSPKNRL QPSQLDPEAS
810 820 830 840 850
ISAILCDKNQ PPTNGQKACQ SDPGLKKQST DPSSILVPEE RKPWADVSLS
860 870 880 890 900
TQGGNEQGSE LPSKGSPCNT PSSSPKDKVL EGAPPSEMSE LSTPLGQESP
910 920 930 940 950
ALGGNEQEGT GSSSQLSEIP PPAAATALTE NLGGKDSLST GQGLSKSQQE
960 970 980 990 1000
LDDALQIGSL REEARCGDSG LSEAGDVLPP PLGLDKTETA SRNRVEALPC
1010 1020 1030 1040 1050
PPDSVALLDT AHYSPDPVPT NPRVTLTQDA LESEACDEGQ KESAPQLEME
1060 1070 1080 1090 1100
QPAPLGTEAQ SPLGSFQKAE ERDGKGGSAE VNVDASEGDP GMQQASEAPE
1110 1120 1130 1140 1150
PALSSGFLQA DQSLASTLSE PRQLVQLEPS CGDALLPAGE TDGMPRSSVD
1160 1170 1180 1190 1200
VLTQHTVSGP QSLLPAEPPD TPYLHINSAA RKDAEDGSTR GAVSSEDPGA
1210 1220 1230 1240 1250
PHESPVKEPP PALENDTLEK TPAVSFTTVL QPGTADGDIS AAGDGNSIGI
1260 1270 1280 1290 1300
PQAGTTEGHV SFMPYLDRMP LPVRDEQMAR EMHVAAAPEA NARPSEIAAC
1310 1320 1330 1340 1350
PASEDAAGER EGNRERPVEL TPDLRVVASG SEGASSKQTS IIAGLPDFRE
1360 1370 1380 1390 1400
HITKIFEQSV LGALAADRPH SKKSGVPRNV LFEGPDVSLN SEKLLDGAQG
1410 1420 1430 1440 1450
VAAALLPVPP AGLQVEKKQE SAVEAESSHQ VPQDPASEKM MGLVGTALEE
1460 1470 1480 1490 1500
SRPGASVEGE RTGEPVQGTQ AHSQQARSRQ ELTVGLPSSA AVQGLPAERA
1510 1520 1530 1540 1550
PDFPVAPQSH ADVDEASAQG DKSHSIKEHL ETLPSNGQQR EDGTWDPTHT
1560 1570 1580 1590 1600
KGLTNLSGSP CALNGSSHGS VLNVPEPISE PLIPSTLEGD RQIEAAVSTA
1610 1620 1630 1640 1650
NMQNMLGNQD APKMLAGGVL TTPLDPSKMA RAAEEAEGDV TPSRAETWAC
1660 1670 1680 1690 1700
ASGDLLETGT TRMLPGVAGN SAHPGSFQDS GCSNRAQVME EDAATLQGDS
1710 1720 1730 1740 1750
QVEDQQAKQQ LGPQLPTPVG HGKPSISSPP EPDESKDEKL HLVAPEELLS
1760 1770 1780 1790 1800
DSIPGTDDVI QPAAPVDPGH PPLADSSHHG DAVSSVSTHL TVQSASPSAA
1810 1820 1830 1840 1850
RASPAPLAPE HTASAPSAAG PGVEVTPTAS PQHLAKNEPR SSDSEEAFET
1860 1870 1880 1890 1900
PESTTPVKAP PAPPPPPPEV TPEPEVIDPP APEEPGCISE PPVVVPDGPR
1910 1920 1930 1940 1950
SSESVEGSPF RPSHSSSAVF DEDKPIASSG TYNLDFDSIE LVDNFQSLEP
1960 1970 1980 1990 2000
CSADSKGQEC KVSTRRKSTE SVPPSKSTLS RSLSLQASDF DGASCPGSPE
2010 2020 2030 2040 2050
AGTLTTDACG TGSNSASSTL KRTKKTRPPS LKKKQATKKP TETPPVKETQ
2060 2070 2080 2090 2100
QEPGEESPVP SEEHLAPETK TESATPEGAG CTLSDDTPLE SPAVPTATCP
2110 2120 2130 2140 2150
LTLESAEDVS PLVSGGGRVQ NSPPVGRKSV PLTTASEAVE VTLSDSGGQE
2160 2170 2180 2190 2200
DLPAKGLSVR LEFDYSEDKG SWESQQENAP PTKKIGKKPV AKMPLRRPKM
2210 2220 2230 2240 2250
KKTPEKLDNT PASPPRSPTE PSDTPIAKGT YTFDIDKWDD PNFNPFSSTS
2260 2270 2280 2290 2300
KMQESPKLSQ QSYNFDPDAC EESLDPFKAS SKTPSSPSKS PASFEIPAST
2310 2320 2330 2340 2350
TEADGDGLNK PAKKKKTPLK TMVEDVMSVC SLFDTFRVKK SPKRSPLSDP
2360 2370 2380 2390 2400
PSQDPTPAAT PEAPSAISTV VHATDEEKLA VTSQKWTCMT VDLDADKQDF
2410 2420 2430 2440 2450
PQPSDLSNFV NETKFNSPSE GKQLGGQPDP HLALENTVPR GQRARKELDY
2460 2470 2480 2490 2500
RNSYEIEYME KLGSSLPQDD DTPKKQALYL MFDTPQESPV KSPPVRMSDS
2510 2520 2530 2540 2550
PTPCSGSSFE DTEALVNAAT KLQHPVARGL PSSQEPLLQV PEKPSQKELE
2560 2570 2580 2590 2600
AMALGTPAEA IEITAPEGAF ASADTLLSRL AHPASLCGAL GYLEPDLAEK
2610 2620 2630 2640 2650
NPPVFAQKLQ EELEFAVMRI EALKLARQIA LASRSRQDTK REAAHPPDVS
2660 2670 2680 2690 2700
ISKTALYSRI GSTEVEKPPG LLFQQPDLDS ALQVARAEVI AKEREVSEWR
2710 2720 2730 2740 2750
DKYEESRREV VEMRKIVAEY EKTIAQMIED EQREKSISHQ TVQQLVLEKE
2760 2770 2780 2790 2800
QALADLNSVE KSLADLFRRY EKMKEVLEGF RKNEEVLKKC AQEYLSRVKK
2810 2820 2830 2840 2850
EEQRYQALKV HAEEKLDRAN AEIAQVRGKA QQEQAAYQAS LRKEQLRVDA
2860 2870
LERTLEQKNK EIEELTKICD ELIAKMGKS
Length:2,879
Mass (Da):305,231
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3DCEFD9D270AE3A2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 13 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9JJG0TACC2_MOUSE
Transforming acidic coiled-coil-con...
Tacc2 MNCb-3527
1,149Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q9Z4E9Q9Z4_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
1,146Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9QL08E9QL08_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
1,036Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LI86A0A140LI86_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
1,020Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LIJ2A0A140LIJ2_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
568Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LIQ1A0A140LIQ1_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
555Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LIQ6A0A140LIQ6_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
829Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LJ29A0A140LJ29_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
696Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LJA0A0A140LJA0_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
910Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LHH8A0A140LHH8_MOUSE
Transforming acidic coiled-coil-con...
Tacc2
1,919Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC145294 Genomic DNA No translation available.
AC175034 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
NP_001004468.1, NM_001004468.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000084513; ENSMUSP00000081561; ENSMUSG00000030852

Database of genes from NCBI RefSeq genomes

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GeneIDi
57752

UCSC genome browser

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UCSCi
uc009kae.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC145294 Genomic DNA No translation available.
AC175034 Genomic DNA No translation available.
RefSeqiNP_001004468.1, NM_001004468.2

3D structure databases

SMRiE9Q8T1
ModBaseiSearch...

PTM databases

iPTMnetiE9Q8T1
PhosphoSitePlusiE9Q8T1

Proteomic databases

jPOSTiE9Q8T1
MaxQBiE9Q8T1
PeptideAtlasiE9Q8T1
PRIDEiE9Q8T1

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
46332, 232 antibodies

Genome annotation databases

EnsembliENSMUST00000084513; ENSMUSP00000081561; ENSMUSG00000030852
GeneIDi57752
UCSCiuc009kae.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
10579
MGIiMGI:1928899, Tacc2

Phylogenomic databases

GeneTreeiENSGT00940000157052
HOGENOMiCLU_000545_0_0_1
OrthoDBi669540at2759
TreeFamiTF333149

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
57752, 1 hit in 16 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Tacc2, mouse

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000030852, Expressed in hindlimb stylopod muscle and 303 other tissues
GenevisibleiE9Q8T1, MM

Family and domain databases

InterProiView protein in InterPro
IPR039915, TACC
IPR007707, TACC_C
PANTHERiPTHR13924, PTHR13924, 1 hit
PfamiView protein in Pfam
PF05010, TACC_C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9Q8T1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q8T1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 7, 2020
This is version 66 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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