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Protein

Olfactory receptor

Gene

Olfr172

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

  • G protein-coupled receptor activity Source: UniProtKB-KW
  • odorant binding Source: GO_Central
  • olfactory receptor activity Source: MGI

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:Olfr172Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:3030006 Olfr172

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 48HelicalUniRule annotationAdd BLAST23
Transmembranei60 – 78HelicalUniRule annotationAdd BLAST19
Transmembranei98 – 120HelicalUniRule annotationAdd BLAST23
Transmembranei140 – 158HelicalUniRule annotationAdd BLAST19
Transmembranei197 – 226HelicalUniRule annotationAdd BLAST30
Transmembranei238 – 260HelicalUniRule annotationAdd BLAST23
Transmembranei272 – 292HelicalUniRule annotationAdd BLAST21

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000071510 Expressed in 7 organ(s), highest expression level in bone marrow macrophage

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093690

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 290G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410J9MS Eukaryota
ENOG41116R8 LUCA
GeneTreeiENSGT00550000074564
InParanoidiE9Q8F6
KOiK04257
OMAiIFFIYIR
OrthoDBiEOG091G0AZH
PhylomeDBiE9Q8F6
TreeFamiTF352737

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q8F6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEGNHTMKH EFILTGFTNH PEMKGLLFAV FFFIYLITMI GNMGLVILIC
60 70 80 90 100
TERSLHTPMY IFLGNLAFID SCCAYAITPK MLENFFSEDR IISLYECMAQ
110 120 130 140 150
FYFLSTVETA DCFLLSAMAY DRYVAICNPL QYHTMMSKKL CLQMITGAFI
160 170 180 190 200
VGNLHSMVHV GLLFRLAFCG SNQINHFYCD ILPLYRLSCV DPYVNELVLL
210 220 230 240 250
VFSAPIQVFT IGCVLISYLF IVYTIFQMKS KEGRIKAFST CASHFLSVSL
260 270 280 290 300
FYGSLFFIYI KPNLLEEGDK DMPAAILFTI VVPLLNPFIY SLRNKEVKNV

LQKILQKNK
Length:309
Mass (Da):35,408
Last modified:April 5, 2011 - v1
Checksum:i678D9D07275E8EBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159200 Genomic DNA No translation available.
RefSeqiNP_667212.2, NM_147001.2
UniGeneiMm.390862

Genome annotation databases

EnsembliENSMUST00000095991; ENSMUSP00000093690; ENSMUSG00000071510
ENSMUST00000214139; ENSMUSP00000150908; ENSMUSG00000071510
GeneIDi259003
KEGGimmu:259003
UCSCiuc007zoe.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC159200 Genomic DNA No translation available.
RefSeqiNP_667212.2, NM_147001.2
UniGeneiMm.390862

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093690

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000095991; ENSMUSP00000093690; ENSMUSG00000071510
ENSMUST00000214139; ENSMUSP00000150908; ENSMUSG00000071510
GeneIDi259003
KEGGimmu:259003
UCSCiuc007zoe.2 mouse

Organism-specific databases

CTDi259003
MGIiMGI:3030006 Olfr172

Phylogenomic databases

eggNOGiENOG410J9MS Eukaryota
ENOG41116R8 LUCA
GeneTreeiENSGT00550000074564
InParanoidiE9Q8F6
KOiK04257
OMAiIFFIYIR
OrthoDBiEOG091G0AZH
PhylomeDBiE9Q8F6
TreeFamiTF352737

Enzyme and pathway databases

ReactomeiR-MMU-381753 Olfactory Signaling Pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000071510 Expressed in 7 organ(s), highest expression level in bone marrow macrophage

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q8F6_MOUSE
AccessioniPrimary (citable) accession number: E9Q8F6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 7, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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