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Entry version 69 (17 Jun 2020)
Sequence version 1 (05 Apr 2011)
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Protein
Submitted name:

YLP motif-containing protein 1

Gene

Ylpm1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
YLP motif-containing protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ylpm1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1926195 Ylpm1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9Q803

PeptideAtlas

More...
PeptideAtlasi
E9Q803

PRoteomics IDEntifications database

More...
PRIDEi
E9Q803

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000021244 Expressed in saccule of membranous labyrinth and 283 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
E9Q803 baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
E9Q803

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 383DisorderedSequence analysisAdd BLAST383
Regioni564 – 1115DisorderedSequence analysisAdd BLAST552

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1293 – 1320Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi13 – 31Pro-richSequence analysisAdd BLAST19
Compositional biasi34 – 74PolarSequence analysisAdd BLAST41
Compositional biasi79 – 116Pro-richSequence analysisAdd BLAST38
Compositional biasi141 – 199Pro-richSequence analysisAdd BLAST59
Compositional biasi200 – 238PolarSequence analysisAdd BLAST39
Compositional biasi253 – 305PolarSequence analysisAdd BLAST53
Compositional biasi346 – 366Pro-richSequence analysisAdd BLAST21
Compositional biasi564 – 658Pro-richSequence analysisAdd BLAST95
Compositional biasi659 – 673PolarSequence analysisAdd BLAST15
Compositional biasi684 – 698Pro-richSequence analysisAdd BLAST15
Compositional biasi699 – 730PolarSequence analysisAdd BLAST32
Compositional biasi752 – 766PolyampholyteSequence analysisAdd BLAST15
Compositional biasi784 – 816Pro-richSequence analysisAdd BLAST33
Compositional biasi823 – 852Pro-richSequence analysisAdd BLAST30
Compositional biasi874 – 888PolarSequence analysisAdd BLAST15
Compositional biasi893 – 924Pro-richSequence analysisAdd BLAST32
Compositional biasi954 – 1061PolyampholyteSequence analysisAdd BLAST108
Compositional biasi1095 – 1115PolyampholyteSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2400 Eukaryota
ENOG410YIR5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000039837

KEGG Orthology (KO)

More...
KOi
K17602

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027417 P-loop_NTPase
IPR026314 YLP_motif_con_p1

The PANTHER Classification System

More...
PANTHERi
PTHR13413 PTHR13413, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

E9Q803-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYPNWGRYGG SSHYPPPPVP PPPPPVALPE ASPGPGYSSS TAPAAPSSSG
60 70 80 90 100
FMSFREQHLA QLQQLQQMHQ KQMQCVLQPH HLPPPPLPPP PVMPGGGYGD
110 120 130 140 150
WQPPPPPMPP PPGPALSYQK QQQYKHQMIH HQRDGPPGLV PMELESPPES
160 170 180 190 200
PPVPPGSYMP PSQSYMPPPQ PPPSYYPPSS AQPYLPPAQP SPSQSPPSQS
210 220 230 240 250
YLAPTPSYSS SSSSQSYLSH SQPYLPPSQA SPSRSSQGPS KPQLPPPPSI
260 270 280 290 300
PSGNKTAIQQ EPLESGAKNK TAEQKQAAPE PDPSTMTPQE QQQYWYRQHL
310 320 330 340 350
LSLQQRTKVH LPGHKKGLVT AKDVPEPIKE EAPGPAASQV AEPLAAEKPP
360 370 380 390 400
LPPPNEEAPP PLSPEEPQSE DSEDSEDSEE DARFKQLKAI AAHWQAAAAH
410 420 430 440 450
WQQQQQQRVG FQYQGIMQRH TQLQQILQQY QQVIQHSPHI QTMSLDVQLR
460 470 480 490 500
HYEMQQQQFQ HLFQDWEREF QLWEEQLHSY PHKDQLQEYE KQWKTWQGHM
510 520 530 540 550
KATQTYLQEK VNSFQTVKSQ YLGNMAMPPP FVPYSQMPPP LPTMPPPVLP
560 570 580 590 600
PSLPPPVMPP ALPTSIPPPG MPPPVMPPSL PTSVPPPGMP PSLSSGPPPV
610 620 630 640 650
LPPPALSSAG SPPVLPPPAL PGGPPILPLP PLSSATPPPG IPPPGAPQGM
660 670 680 690 700
PPQLTAPLPP ASGSQNSQIP EKPRQALLPT PVSFGSTPPS PYHPPPQSEQ
710 720 730 740 750
VNSKPLNKVF SSEQGLGESS ALSQSIIAAK DTPVKSGGLL ADPPKGSFLE
760 770 780 790 800
GPRGPREQKE QLQKLKDFGS EPQMADHLPP PDSRLQNPSR PGMYPPPGSY
810 820 830 840 850
RPPPPMGKPP GSIVRPSAPP ARSSIPMTRP PVPIPPPPPP PPPPPPPPPV
860 870 880 890 900
IKSKTSSVKQ ERWDEDSFFG LWDTNDDQGL NSEFKRDTAT IPSAPVLPPP
910 920 930 940 950
PVHSSIPPPG PMPMGMPPMS KPPPVQHTVD YGHGRDMPTN KVEQIPYGER
960 970 980 990 1000
ITLRPDPLPE RSTFDADHAG QRDRYDRDRD REPYFDRPSN ITDHRDFKRD
1010 1020 1030 1040 1050
RETHRDRDRD RVLDYERDRF DRERRPRDDR NQSYRDKKDH SSSRRGGFDR
1060 1070 1080 1090 1100
PSYDRKSDRP PYEGPPMFGG ERRTYPEERM PLPAPALGHQ PPPVPRVEKK
1110 1120 1130 1140 1150
PESKNVDDIL KPPGRESRPE RIVVIMRGLP GSGKTHVAKL IRDKEVEFGG
1160 1170 1180 1190 1200
PAPRVLSLDD YFIAEVEKEE KDPDSGKKVK KKVMEYEYEA DMEETYRTSM
1210 1220 1230 1240 1250
FKTFKKTLDD GFFPFIILDA INDRVRHFDQ FWSAAKTKGF EVYLAEMSAD
1260 1270 1280 1290 1300
NQTCGKRNIH GRKLKEINKM AEHWEVAPRH MMRLDIRSLL QDAAIEEVEM
1310 1320 1330 1340 1350
EDFDANIEDQ KEEKKDAEEE ESELGYIPKS KWEMDTSEAK LDKLDGLRTG
1360 1370 1380 1390 1400
TKRKRDWEAI ASRMEDYLQL PDDYETRASE PGKKRVRWAD LEEKKDADRK
1410 1420 1430
RAIGFVVGQT DWEKITDESG HLAERALNRT KYI
Length:1,433
Mass (Da):160,042
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA9A9DA2842AC8ECD
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9R0I7YLPM1_MOUSE
YLP motif-containing protein 1
Ylpm1 Zap, Zap3
1,386Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YWX2D3YWX2_MOUSE
YLP motif-containing protein 1
Ylpm1
2,139Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6YTL8F6YTL8_MOUSE
YLP motif-containing protein 1
Ylpm1
1,577Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC127582 Genomic DNA No translation available.
AC155811 Genomic DNA No translation available.
CR974585 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
NP_001334350.1, NM_001347421.1
XP_006516164.1, XM_006516101.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000168977; ENSMUSP00000128962; ENSMUSG00000021244

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
56531

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:56531

UCSC genome browser

More...
UCSCi
uc007oge.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC127582 Genomic DNA No translation available.
AC155811 Genomic DNA No translation available.
CR974585 Genomic DNA No translation available.
RefSeqiNP_001334350.1, NM_001347421.1
XP_006516164.1, XM_006516101.3

3D structure databases

SMRiE9Q803
ModBaseiSearch...

Proteomic databases

MaxQBiE9Q803
PeptideAtlasiE9Q803
PRIDEiE9Q803

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
62380 14 antibodies

Genome annotation databases

EnsembliENSMUST00000168977; ENSMUSP00000128962; ENSMUSG00000021244
GeneIDi56531
KEGGimmu:56531
UCSCiuc007oge.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56252
MGIiMGI:1926195 Ylpm1

Phylogenomic databases

eggNOGiKOG2400 Eukaryota
ENOG410YIR5 LUCA
GeneTreeiENSGT00440000039837
KOiK17602

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
56531 6 hits in 14 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ylpm1 mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000021244 Expressed in saccule of membranous labyrinth and 283 other tissues
ExpressionAtlasiE9Q803 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR026314 YLP_motif_con_p1
PANTHERiPTHR13413 PTHR13413, 2 hits
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiE9Q803_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q803
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 17, 2020
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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