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Protein

Cadherin-related family member 2

Gene

Cdhr2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion, Differentiation
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cadherin-related family member 2Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cdhr2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2687323 Cdhr2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini21 – 1152ExtracellularCuratedAdd BLAST1132
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1153 – 1173HelicalSequence analysisAdd BLAST21
Topological domaini1174 – 1308CytoplasmicCuratedAdd BLAST135

Keywords - Cellular componenti

Cell junction, Cell membrane, Cell projection, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500324310721 – 1308Cadherin-related family member 2Sequence analysisAdd BLAST1288

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1245PhosphoserineBy similarity1
Modified residuei1297PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
E9Q7P9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
E9Q7P9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
E9Q7P9

PRoteomics IDEntifications database

More...
PRIDEi
E9Q7P9

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
E9Q7P9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
E9Q7P9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000034918 Expressed in 46 organ(s), highest expression level in intestine

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
E9Q7P9 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the IMAC/intermicrovillar adhesion complex/intermicrovillar tip-link complex composed of ANKS4B, MYO7B, USH1C, CDHR2 and CDHR5. Interacts with MAST2 (By similarity). Interacts (via cytoplasmic domain) with USH1C and MYO7B; required for proper localization of CDHR2 to microvilli tips and its function in brush border differentiation (Probable).By similarity1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000043596

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11308
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5CYXX-ray2.10A21-348[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
E9Q7P9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
E9Q7P9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini33 – 124Cadherin 1PROSITE-ProRule annotationAdd BLAST92
Domaini125 – 241Cadherin 2PROSITE-ProRule annotationAdd BLAST117
Domaini242 – 353Cadherin 3PROSITE-ProRule annotationAdd BLAST112
Domaini368 – 480Cadherin 4PROSITE-ProRule annotationAdd BLAST113
Domaini481 – 586Cadherin 5PROSITE-ProRule annotationAdd BLAST106
Domaini586 – 695Cadherin 6PROSITE-ProRule annotationAdd BLAST110
Domaini695 – 807Cadherin 7PROSITE-ProRule annotationAdd BLAST113
Domaini809 – 927Cadherin 8PROSITE-ProRule annotationAdd BLAST119
Domaini929 – 1051Cadherin 9PROSITE-ProRule annotationAdd BLAST123

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1178 – 1308Mediates interaction with USH1C and MYO7B and is required for proper localization to microvilli tips and function in microvilli organizationBy similarityAdd BLAST131

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The cadherin 1 domain is required for binding to CDHR5.By similarity

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3594 Eukaryota
ENOG410XQHI LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161160

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115467

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG053524

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
E9Q7P9

KEGG Orthology (KO)

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KOi
K16502

Identification of Orthologs from Complete Genome Data

More...
OMAi
NVICTKA

Database of Orthologous Groups

More...
OrthoDBi
83119at2759

TreeFam database of animal gene trees

More...
TreeFami
TF332908

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR030276 CDHR2

The PANTHER Classification System

More...
PANTHERi
PTHR44787 PTHR44787, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00028 Cadherin, 7 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205 CADHERIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112 CA, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313 SSF49313, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232 CADHERIN_1, 5 hits
PS50268 CADHERIN_2, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

E9Q7P9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAWLWLLCAL LPAFMVSVTA NSPPSFGVNM TLVTLPEDLP VGAVAFWLVA
60 70 80 90 100
TDSDNDHLTY GISGPNASYF SVNANTGEVK LASPLDFETV PFFKITISTS
110 120 130 140 150
DGLNIRTAEM QVIVEDRNDN IPVFLNTEFS TSINETLPVG SVVFSVLAED
160 170 180 190 200
KDTGTAGLVQ YFIEKVIPST ANSNNLFRIL ENGSIVLNDT LSYNNKSAFY
210 220 230 240 250
QLELKACDSG GILDNKPKTQ CSQPVFVSIS VIDEPDLDPR FIREFYSASV
260 270 280 290 300
AEDATLGTSV LTVEAVDSDK GINDIVTYSV SNSTRPGWFD IREDGVIFVN
310 320 330 340 350
GSLDREQLLL ENEEVQIQVT ATEKNLNIYG QEAKASMWVT IRVTDVNDHK
360 370 380 390 400
PEFYNCSLPG CSFSPQEAQV NFIGYVDEHA SARISIDGLT MVAYDPDQGD
410 420 430 440 450
NGTFLLSLNG QDAEAFNVSP ERAAGSVSVQ VVVRNSEMVD YEKETVMVVE
460 470 480 490 500
VVATDSVSNN YSVATVTIHL RNINDHRPVF SQSLYELTVP EHCPTGYLVT
510 520 530 540 550
DKIQATDLDG DEWGPITYSL LPGNGADLFE VEPNSGNLTV KNGTLLDREK
560 570 580 590 600
QAVYYLTLQA TDGGNQSTTT ALEITLLDIN DNPPVVRGSY NVFVPEENGN
610 620 630 640 650
VSVTIQAYDD DQPDTNNSLL VFSLLPGPYS SNFSLDPNTG LLRNLGPLDR
660 670 680 690 700
EAIDPALEGR IVLTVIVADC GEPSLSTNVN VTITVEDIND NLPVFNQSYE
710 720 730 740 750
FSVWERVPGA WVGTVKAWDA DQTAANNRIS FSLSGTGANN FILQGNVLEQ
760 770 780 790 800
GWAEGSLWLL PDVRLDYETQ KFFHLTVSAE NPGPQGLDST ANVTVTVMDV
810 820 830 840 850
NDEPPTLDAA SLQAISVTEN GSEHGQVTRV IAQDVDTAAL LRIELVDVIC
860 870 880 890 900
TKAGVDVGSV CHGWFSVDGN GSVYINQSEA IDYEACHLVT LVVRAYDLNT
910 920 930 940 950
DPGFDAYSSN GSLLINIKDK NDNAPYFLPN NQTFVIIPEL VLPNQQVASV
960 970 980 990 1000
QARDEDSEDN GIIMFSILKA EFVRKDGTSN PVQVFRITRS VEAGLFTGSI
1010 1020 1030 1040 1050
ELVTNLDSTI QGTYQVTVQA QDQPTLGPAL ETQTTLNLFT VDQSYRVRLQ
1060 1070 1080 1090 1100
FSTSKEDVGA NMEEIKEALI QATRTSVYVV TIQNIDSTAR ARASSYMDAY
1110 1120 1130 1140 1150
FVFSNGTALT LTELNMMIRK DQDALRQLLQ LGLVVVSSQE SQEPDQQKLL
1160 1170 1180 1190 1200
TSVIIGLVVS LVLVLVILIT ALVCLRKSYH RKLRAMKAGK EARKTPIETT
1210 1220 1230 1240 1250
APTAAIPGTN MYNTDRANPV LDLPTKDLGL ECHSSSDLDY DSLNSLDENS
1260 1270 1280 1290 1300
VDLDMDSKEF KRKDLPGDPP EPDPEPLTAV LSGRSAGASE QQKKNLSFTN

PGLDTTDL
Length:1,308
Mass (Da):142,633
Last modified:April 5, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C1DD3E53E556A0A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti371N → D in BAE25870 (PubMed:16141072).Curated1
Sequence conflicti697Q → QS in AAI41302 (PubMed:15489334).Curated1
Sequence conflicti697Q → QS in AAI45625 (PubMed:15489334).Curated1
Sequence conflicti704W → C in AAI45625 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK144400 mRNA Translation: BAE25870.1
AC162526 Genomic DNA No translation available.
BC141301 mRNA Translation: AAI41302.1
BC145624 mRNA Translation: AAI45625.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS36669.1

NCBI Reference Sequences

More...
RefSeqi
NP_001028536.2, NM_001033364.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.315382

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000037145; ENSMUSP00000043596; ENSMUSG00000034918

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
268663

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:268663

UCSC genome browser

More...
UCSCi
uc007qoz.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK144400 mRNA Translation: BAE25870.1
AC162526 Genomic DNA No translation available.
BC141301 mRNA Translation: AAI41302.1
BC145624 mRNA Translation: AAI45625.1
CCDSiCCDS36669.1
RefSeqiNP_001028536.2, NM_001033364.3
UniGeneiMm.315382

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5CYXX-ray2.10A21-348[»]
ProteinModelPortaliE9Q7P9
SMRiE9Q7P9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000043596

PTM databases

iPTMnetiE9Q7P9
PhosphoSitePlusiE9Q7P9

Proteomic databases

jPOSTiE9Q7P9
MaxQBiE9Q7P9
PaxDbiE9Q7P9
PRIDEiE9Q7P9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000037145; ENSMUSP00000043596; ENSMUSG00000034918
GeneIDi268663
KEGGimmu:268663
UCSCiuc007qoz.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
54825
MGIiMGI:2687323 Cdhr2

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00940000161160
HOGENOMiHOG000115467
HOVERGENiHBG053524
InParanoidiE9Q7P9
KOiK16502
OMAiNVICTKA
OrthoDBi83119at2759
TreeFamiTF332908

Miscellaneous databases

Protein Ontology

More...
PROi
PR:E9Q7P9

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000034918 Expressed in 46 organ(s), highest expression level in intestine
GenevisibleiE9Q7P9 MM

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR030276 CDHR2
PANTHERiPTHR44787 PTHR44787, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 7 hits
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 9 hits
SUPFAMiSSF49313 SSF49313, 9 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 5 hits
PS50268 CADHERIN_2, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCDHR2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: E9Q7P9
Secondary accession number(s): B7ZP46, B9EJ32, Q3UN77
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2016
Last sequence update: April 5, 2011
Last modified: January 16, 2019
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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