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Protein
Submitted name:

Dynein, axonemal, heavy chain 11

Gene

Dnah11

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynein, axonemal, heavy chain 11Imported
Gene namesi
Name:Dnah11Imported
Synonyms:Dnahc11Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1100864 Dnah11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q7N9
PaxDbiE9Q7N9
PeptideAtlasiE9Q7N9
PRIDEiE9Q7N9

Expressioni

Gene expression databases

BgeeiENSMUSG00000018581 Expressed in 107 organ(s), highest expression level in floor plate of midbrain
ExpressionAtlasiE9Q7N9 baseline and differential
GenevisibleiE9Q7N9 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000081867

Structurei

3D structure databases

ProteinModelPortaliE9Q7N9
SMRiE9Q7N9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1869 – 1963AAAInterPro annotationAdd BLAST95
Domaini2474 – 2619AAAInterPro annotationAdd BLAST146
Domaini2819 – 2931AAAInterPro annotationAdd BLAST113

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1256 – 1290Sequence analysisAdd BLAST35
Coiled coili3127 – 3147Sequence analysisAdd BLAST21
Coiled coili3292 – 3361Sequence analysisAdd BLAST70
Coiled coili3646 – 3673Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00760000118964
InParanoidiE9Q7N9
KOiK10408
OMAiQMQESTH
OrthoDBiEOG091G00Z2
TreeFamiTF316836

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 3 hits
SUPFAMiSSF52540 SSF52540, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

E9Q7N9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAQEEGTVL RLSPSEQEDE EDEEAAAARR VQRFALDPRV RFLGGRLRQA
60 70 80 90 100
LRFPEETWGQ YLESDDHRQV LGDFLESTGP ASLVFSVATA GRLSASPEIP
110 120 130 140 150
RDVKHKLVYF AKKMTENMGE SDFSQTILFG EIPRSLLTHV TAFLDEILVP
160 170 180 190 200
VLSNKNNHTS WSCFISQDVE HHTEVMKNKM HIFRGKMSRR THLPIPTIAE
210 220 230 240 250
NIDLDQHYLV TRPQSDERRI LHAIESLVIK WSHQIQEIIE KDSAHPLLSG
260 270 280 290 300
LHPTPETELD FWTMRHDNLK CIYSQLQAPI VLKMVKILRT RQSSYLPALK
310 320 330 340 350
GIFTTVENAL LEAQDVELHL RPLRRHIHSL QEAEFPQTRI LIAPLLHTIC
360 370 380 390 400
LIWSHSKFYN TPARVIVLLQ EFCNLFIDQA RAYLSPEDLL KGEIEDALEK
410 420 430 440 450
VQVAISVLKT FQNSFFKYRK GLTSYFTRNT EQRSWDFQSH LVFGRFNKFL
460 470 480 490 500
DRLVKIEDMF VTILEFEKLE RLEFGGSKGA VLNAQIHSTS EEFIECCKVF
510 520 530 540 550
QQSTYDPSDC DDMEFESDYF KFKSRTLDFD RRLGTLLCEG LSNCSGLESA
560 570 580 590 600
FKLLTIFGNF LEKPVVMEMF SPHYSTLLNM FNAELDVCKQ LYDEHMKQIE
610 620 630 640 650
HGHEILNKNM PFTSGNIKWA RMLLERLQMF WSNFTSLHYL FPDSPDEAAV
660 670 680 690 700
CQKYAEMTTL LDQFESHIYS EWRRNVDETC EFNLNQPLVK FSPINGLLSV
710 720 730 740 750
NFDPKLVAVL REVKYLLMLK KSDIPDSALG IFQKRNIILK YIGNLELLVQ
760 770 780 790 800
GYNKLKQTLL EVEYPLIEDE LGAIDEQLRV AATWLTWQDD FWVYMERVQV
810 820 830 840 850
ATAELECRVS QTQSNMLTIQ QTMQAWAEWP LLPRRETRRE AALTLDDKGD
860 870 880 890 900
LFAKKYKLIR EDGCKIHNLV EENRKLFRAD PSLDSWKIYV EFIDDIVVEG
910 920 930 940 950
FFQAILHDLD FFLRNTEKQL KPTPFFQAQM LLMPPEIVFK PPLEKEAGDG
960 970 980 990 1000
FYDLVEEMLC GSFRVSAQMG RVAAHLDIAD YQNDMDNMLG LAEVRQEIMN
1010 1020 1030 1040 1050
RVADVINKVL EFRSSLETYS YLWVDDRVEI LRQFLLYGHA VPSEEMDAPA
1060 1070 1080 1090 1100
SEDILQPPTL EQFKEQIDIY EALYIQMSKF DDFRVFNSWF KVDMRPFKLS
1110 1120 1130 1140 1150
LLNVIKKWSW MFQEHLLRFV VDSLSELQGF IKQTNAGLQR QLCEGDHDGL
1160 1170 1180 1190 1200
VDIMGHLLAV RSRQRATDEL FEPLKETIML LESYGQKMPE QVYAQLEELP
1210 1220 1230 1240 1250
ERWETTKKIA AMVRHEVSPL QNAEVTLIRK KCILFDEKQA EFRERFRSYA
1260 1270 1280 1290 1300
PLGFKAENPY AVLDKANQEL EALEEEMEQM QNSARLFEVA LPEYKQMKQC
1310 1320 1330 1340 1350
RQEIRLLKGL WDVIIYVRRS IDNWTETQWR QINVEQMDLE LRRFAKEIWS
1360 1370 1380 1390 1400
LDKAVRVWDA YSGLEGTVKD MTTSLRAIAE LQNPALRDRH WQQLMKAIGV
1410 1420 1430 1440 1450
RFSINDSTTL SDLLAVQLHR VEDDVRDIVD QAVKELGTEK VITDVSHTWE
1460 1470 1480 1490 1500
ALEFSYEAHH RTGTPLLKSD EQLFETLEHN QVQLQSLLQS KYVEYFIEQV
1510 1520 1530 1540 1550
LSWQNKLNVA DAVIFTWMQV QRTWSHLESI FVCSEDIRVQ LVEDARRFDK
1560 1570 1580 1590 1600
VDAEFKELMF ETAKVKNVLE ATCRPHLYEK LKDFQHRLSL CEKALAEYLE
1610 1620 1630 1640 1650
TKRVTFPRFY FISSADLLDI LSKGAQPKQV THHLVKLFDS ISDLQFEDNL
1660 1670 1680 1690 1700
DVSTHKAVGM FSKEKEYVPF QAGCECIGHV ESWLLQLEQT MKDTVRLAIT
1710 1720 1730 1740 1750
EAITAYEEKP RELWIFDFPA QVALTGSQIW WTTDVGIAFS RLEEGYETAL
1760 1770 1780 1790 1800
KDFHKKQISQ LNTLITLLLG ELSPGDRQKV MTICTIDVHA RDVVAKLISQ
1810 1820 1830 1840 1850
KVVSPHAFTW LSQLRHEWED SRKHCVVNIC DAHFQYFYEY LGNSPRLVIT
1860 1870 1880 1890 1900
PLTDRCYITL TQSLHLTMSG APAGPAGTGK TETTKDLGRA LGMMVYVFNC
1910 1920 1930 1940 1950
SEQMDYRSIG NIYKGLVQTG AWGCFDEFNR IAVEVLSVVA VQVKMIHDAI
1960 1970 1980 1990 2000
RNGRKRFVFL GETIPLKPSV GIFITLNPGY AGRTELPENL KALFRPCAMV
2010 2020 2030 2040 2050
APDTELICEI MLVAEGFVDA RSLARKFISL YTLCEELLSK QDHYDWGLRA
2060 2070 2080 2090 2100
IKSVLVVAGS LKRGDKNRPE DQVLMRALRD FNMPKIVTDD VPVFLGLVSD
2110 2120 2130 2140 2150
LFPALDVPRQ RKPHFEQMVK QSTLELRLQP EESFILKVVQ LEELLAVRHS
2160 2170 2180 2190 2200
VFVVGNAGTG KSKILRTLNR TYVNMKQKPV WSDLNPKAVT TDELFGFIHH
2210 2220 2230 2240 2250
ATREWKDGLF SSILREQANL THDGPTWIVL DGDIDPLWIE SLNTVMDDNK
2260 2270 2280 2290 2300
VLTLASNERV ALKPSMRLLF ETHHLRTATP ATVSRAGILY VNPQDLGWNP
2310 2320 2330 2340 2350
YVASWIDRRR HQSEKANLTI LFDKYIPVCL EKLRTSFKAI TSVPESSLVQ
2360 2370 2380 2390 2400
TICTLLECLL TPENIPPDSP KETYEVYFAF ACVWTFGGTL LRDQLSDYQA
2410 2420 2430 2440 2450
DFSRWWHKEM KAVKFPSQGT IFDYYLDHKT KKFLPWTDKV PQFSMDADAP
2460 2470 2480 2490 2500
LKTVLVHTPE TTRLRYFTEL LLCKGKPIML VGNAGVGKTV FLSNTLASLS
2510 2520 2530 2540 2550
ENYIVSCVPF NYYTTSAALQ RILEKPLEKK AGRNYGPKGN KKLVYFIDDL
2560 2570 2580 2590 2600
NMPEVDLYGT IQPHALLRQH IDYGHWYDRH KIMLKEIRNC QYVACMNPMV
2610 2620 2630 2640 2650
GSFTVNPRLQ RHFTVFAFNF PSLDALTTIY GQIFSFYLQQ QAFCPSVLRA
2660 2670 2680 2690 2700
GPSLIQATIA FHQMMAESFV PTAIKFHYNF NLRDLSNIFQ GILFASPECL
2710 2720 2730 2740 2750
KSLEDLARLW LHETSRVYGD RLIDTNDFDL FQRKMLETAH KYFKGVDANA
2760 2770 2780 2790 2800
LLRQPLVYCH FASGGEDPCY MPVKDWEGLK AVLMEMVDNY NELHSAMHLV
2810 2820 2830 2840 2850
LFEDAMQHVC RISRILRIPQ GHALLIGVGG SGKQSLSRLA AYICSLEVFQ
2860 2870 2880 2890 2900
ITLTEGYGAQ ELRVDLANLY VRTGAKNMPT VFLLTDAHVL DESFLVLIND
2910 2920 2930 2940 2950
LLASGDIPDL FSDEDMDKII SGIRNEVRGL GLVDSRENCW AFFLARVRQQ
2960 2970 2980 2990 3000
LKMVFCFSPV GHTLRVRARK FPAIVNCTAI DWFHEWPQEA LVSVSRRFIE
3010 3020 3030 3040 3050
EIEGIEPQHK DSISLFMAHV HTSVKEVSAW YYQNERRYNY TTPRSFLEQI
3060 3070 3080 3090 3100
SLFKSLLKKK REEVKQKQEH LGNGIQKLQT TASQVGNLKS RLASQEAELQ
3110 3120 3130 3140 3150
LRNLDAEALI TKIGLQTEKV SREKAIADAE ERKVAAIQTE ASQKQRECEA
3160 3170 3180 3190 3200
DLLKAEPALV AAKDALNTLN RVNLTELKTF PNPPNAVTNV TAAVMVLLAP
3210 3220 3230 3240 3250
RGRVPKDRSW KAAKIFMGKV DDFLQALINY DKEHIPENCL KVVNEQYLKD
3260 3270 3280 3290 3300
PEFNPNLIRT KSFAAAGLCA WVINIIRFYE VYCDVEPKRQ ALAQTNLDLA
3310 3320 3330 3340 3350
AATEKLEAVR RKLVDLDHNL SRLTASFEKA TAEKVRCQEE VNQTNKTIDL
3360 3370 3380 3390 3400
ANKLVSELES EKIRWGQSIK SFETQEKTLC GDVLLTAAFV SYIGSFTRQY
3410 3420 3430 3440 3450
RQELVDCKWI PFLQQKVSIP IAEGLDLIAM LTDDATIATW NNEGLPSDRM
3460 3470 3480 3490 3500
STENATILTH CERWPLMIDP QQQGIKWIKN KYGPDLKVTH LGQKGFLNTI
3510 3520 3530 3540 3550
ETALAFGDVI LIENLKETVD PVLGPLLGRN TTKKGKFIRI GDKECEFNKN
3560 3570 3580 3590 3600
FRLILHTKLA NPHYKPELQA QTTLLNFTVT EDGLEGQLLA EVVSIERPDL
3610 3620 3630 3640 3650
ERLKLVLTKQ QNDFKIELRQ LEDDLLLRLS AAEGSFLDDT DLVERLETTK
3660 3670 3680 3690 3700
ATAAEIEHKV TEARENERKI NETRECYRPV AARASLLYFV ISDLRRINPV
3710 3720 3730 3740 3750
YQFSLKAFNT LFHRAIEQAD KVEDTQERIC ALIESITHAT FLYASQALFE
3760 3770 3780 3790 3800
RDKLTFLSQM AFQILLRRNE IHPLELDFLL RFTVEHTYSS PVDFLTAQSW
3810 3820 3830 3840 3850
SAVKAVALME EFRGLDRDVE GSAKQWRKWV ESECPEKEKL PQEWKKKSLI
3860 3870 3880 3890 3900
QKLIILRAVR PDRMTYALRN FVEEKLGAKY VERTRLDLGK AFEESSPSTP
3910 3920 3930 3940 3950
VFFILSPGVD ALKDLEVLGK RLGFTIDSGK FHNVSLGQGQ ELVAEMAMEK
3960 3970 3980 3990 4000
AAAGGHWVIL QNVHLVAKWL GTLEKLLEKF SQGSHRDYRV FLSAETVPSQ
4010 4020 4030 4040 4050
HEPIIPQGLL ENSIKITNEP PTGMLANLHA ALYNFDQDTL EMCSKDQEFK
4060 4070 4080 4090 4100
SILFSLCYFH ACVAGRLRFG PQGWSRSYPF SPGDLTICTN ILYNYLEANP
4110 4120 4130 4140 4150
NVPWEDLRYL FGEIMYGGHI TDAWDRKLCR VYLEEFMNPS LIEDEVMLAP
4160 4170 4180 4190 4200
GFAAPPYSDY SGYHQYIEDT LPPESPALYG LHPNAEIELL TVTSNTLFRT
4210 4220 4230 4240 4250
LLEMQPRNAV SQEELGQSTE DKVKNILDDI LERLPEEFNM AEIMQKNPNR
4260 4270 4280 4290 4300
SPYVLVCFQE CERMNVLIRE IRVSLQHLDL GLKGELTLSP DVETQLSALS
4310 4320 4330 4340 4350
YDRVPDTWNK LAYPSTYGLA QWFNDLLLRC RELDTWTQDL TLPAVVWLSG
4360 4370 4380 4390 4400
FFNPQSFLTA IMQTMARKNE WPLDRMCLTI DVTKKTKEDY GHPPREGAYL
4410 4420 4430 4440 4450
HGLHLEGARW DIQSGALVDA RLKELTSMMP VIFAKAVPVD RQEIKHAYEC
4460 4470 4480
PVYKTKARGP TYVWTFRLRS KDRIAKWVLA GVALLLEA
Length:4,488
Mass (Da):516,318
Last modified:October 3, 2012 - v2
Checksum:i896C5CF7C5892881
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BLD7H3BLD7_MOUSE
Dynein, axonemal, heavy chain 11
Dnah11 Dnahc11
1,688Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139993 Genomic DNA No translation available.
AC163032 Genomic DNA No translation available.
AC163278 Genomic DNA No translation available.
AC163688 Genomic DNA No translation available.
AC167979 Genomic DNA No translation available.
RefSeqiNP_034190.3, NM_010060.3
UniGeneiMm.390540

Genome annotation databases

EnsembliENSMUST00000084806; ENSMUSP00000081867; ENSMUSG00000018581
GeneIDi13411
KEGGimmu:13411
UCSCiuc007pie.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139993 Genomic DNA No translation available.
AC163032 Genomic DNA No translation available.
AC163278 Genomic DNA No translation available.
AC163688 Genomic DNA No translation available.
AC167979 Genomic DNA No translation available.
RefSeqiNP_034190.3, NM_010060.3
UniGeneiMm.390540

3D structure databases

ProteinModelPortaliE9Q7N9
SMRiE9Q7N9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000081867

Proteomic databases

MaxQBiE9Q7N9
PaxDbiE9Q7N9
PeptideAtlasiE9Q7N9
PRIDEiE9Q7N9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000084806; ENSMUSP00000081867; ENSMUSG00000018581
GeneIDi13411
KEGGimmu:13411
UCSCiuc007pie.1 mouse

Organism-specific databases

CTDi8701
MGIiMGI:1100864 Dnah11

Phylogenomic databases

eggNOGiKOG3595 Eukaryota
COG5245 LUCA
GeneTreeiENSGT00760000118964
InParanoidiE9Q7N9
KOiK10408
OMAiQMQESTH
OrthoDBiEOG091G00Z2
TreeFamiTF316836

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018581 Expressed in 107 organ(s), highest expression level in floor plate of midbrain
ExpressionAtlasiE9Q7N9 baseline and differential
GenevisibleiE9Q7N9 MM

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR035699 AAA_6
IPR011704 ATPase_dyneun-rel_AAA
IPR035706 DHC_D5
IPR026983 DHC_fam
IPR024743 Dynein_HC_stalk
IPR024317 Dynein_heavy_chain_D4_dom
IPR004273 Dynein_heavy_dom
IPR013594 Dynein_heavy_dom-1
IPR013602 Dynein_heavy_dom-2
IPR027417 P-loop_NTPase
PANTHERiPTHR10676 PTHR10676, 1 hit
PfamiView protein in Pfam
PF07728 AAA_5, 1 hit
PF12774 AAA_6, 1 hit
PF12780 AAA_8, 1 hit
PF12781 AAA_9, 1 hit
PF08385 DHC_N1, 1 hit
PF08393 DHC_N2, 1 hit
PF03028 Dynein_heavy, 1 hit
PF12777 MT, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 3 hits
SUPFAMiSSF52540 SSF52540, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q7N9_MOUSE
AccessioniPrimary (citable) accession number: E9Q7N9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 3, 2012
Last modified: November 7, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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